(Q37309853)

19 August 2017

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title

Xenotransplantation of solid organs in the pig-to-primate model (English)

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19 August 2017

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4

David K C Cooper

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19 August 2017

Burcin Ekser

1

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19 August 2017

Paolo Rigotti

series ordinal

2

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19 August 2017

Bruno Gridelli

series ordinal

3

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19 August 2017

publication date

26 October 2008

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19 August 2017

published in

Transplant Immunology

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19 August 2017

volume

21

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19 August 2017

issue

2

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19 August 2017

page(s)

87-92

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Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man.

19 August 2017

cites work

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7 January 2021

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Cloned pigs produced by nuclear transfer from adult somatic cells

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Production of alpha 1,3-galactosyltransferase-deficient pigs

7 January 2021

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Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations

7 January 2021

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Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience

7 January 2021

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alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors

7 January 2021

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Incidence of hyperacute rejection in pig-to-primate transplantation using organs from hDAF-transgenic donors

7 January 2021

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A human CD46 transgenic pig model system for the study of discordant xenotransplantation

7 January 2021

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Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection

7 January 2021

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Cytomegalovirus early promoter induced expression of hCD59 in porcine organs provides protection against hyperacute rejection.

7 January 2021

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Animal transgenesis: state of the art and applications

7 January 2021

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Pigs taking wing with transposons and recombinases.

7 January 2021

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Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium.

7 January 2021

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Recent advances in pig-to-human organ and cell transplantation

7 January 2021

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Alpha1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here?

7 January 2021

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Progress in xenotransplantation following the introduction of gene-knockout technology

7 January 2021

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Discordant organ xenotransplantation in primates: world experience and current status

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Pathology of renal xenograft rejection in pig to non-human primate transplantation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Delayed xenograft rejection of pig-to-baboon cardiac transplants after cobra venom factor therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Physiological aspects of pig-to-primate renal xenotransplantation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

C1-Inhibitor for treatment of acute vascular xenograft rejection in cynomolgus recipients of h-DAF transgenic porcine kidneys

7 January 2021

1 reference

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Cyclophosphamide-induced postoperative anemia in cynomolgus monkey recipients of hDAF-transgenic pig organ xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

The alpha-Gal analog GAS914 ameliorates delayed rejection of hDAF transgenic pig-to-baboon renal xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Evaluation of different alpha-Galactosyl glycoconjugates for use in xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Analysis of the control of the anti-gal immune response in a non-human primate by galactose alpha1-3 galactose trisaccharide-polyethylene glycol conjugate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Treatment with rabbit antithymocyte serum permits a cyclophosphamide-free approach to prevention of hDAF transgenic porcine kidney xenograft rejection in baboons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

The role of anti-non-Gal antibodies in the development of acute humoral xenograft rejection of hDAF transgenic porcine kidneys in baboons receiving anti-Gal antibody neutralization therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Alterations in the coagulation profile in renal pig-to-monkey xenotransplantation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Liver xenografts for the treatment of acute liver failure: clinical and experimental experience and remaining immunologic barriers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Pig-to-baboon liver xenografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Life-supporting human complement regulator decay accelerating factor transgenic pig liver xenograft maintains the metabolic function and coagulation in the nonhuman primate for up to 8 days.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Assessment of renal function during the postoperative period following liver xenotransplantation from transgenic pig to baboon.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Prevention of Hyperacute Rejection in a Model of Orthotopic Liver Xenotransplantation From Pig to Baboon Using Polytransgenic Pig Livers (CD55, CD59, and H-Transferase)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

HDAF transgenic pig livers are protected from hyperacute rejection during ex vivo perfusion with human blood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Classical pathway complement destruction is not responsible for the loss of human erythrocytes during porcine liver perfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

The pig-to-primate immune response: relevance for xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Complement activation in discordant hepatic xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Xenotransplantation of the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Mechanisms of resistance to injury in pig livers perfused with blood from patients in liver failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Prolonged function of extracorporeal hDAF transgenic pig livers perfused with human blood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Three-month survival of HDAFF transgenic pig hearts transplanted into primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Cardiac xenotransplantation: recent preclinical progress with 3-month median survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Anti-CD154 monoclonal antibody and thromboembolism revisted

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Life supporting function for over one month of a transgenic porcine heart in a baboon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Pig-to-non-human primate heart transplantation: immunologic progress over 20 years

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Allosensitized humans are at no greater risk of humoral rejection of GT-KO pig organs than other humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Late onset of development of natural anti-nonGal antibodies in infant humans and baboons: implications for xenotransplantation in infants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Antibodies directed to pig non-Gal antigens in naïve and sensitized baboons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Carbohydrates in xenotransplantation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Extended coagulation profiles of healthy baboons and of baboons rejecting GT-KO pig heart grafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

The utility of right ventricular endomyocardial biopsy for the diagnosis of xenograft rejection after CD46 pig-to-baboon cardiac transplantation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Shear-induced platelet aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

The role of antibodies and von Willebrand factor in discordant pulmonary xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Non-anti-Gal alpha1-3Gal antibody mechanisms are sufficient to cause hyperacute lung dysfunction in pulmonary xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Absence of replication-competent human-tropic porcine endogenous retroviruses in the germ line DNA of inbred miniature Swine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Search for cross-species transmission of porcine endogenous retrovirus in patients treated with living pig tissue. The XEN 111 Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Xenotransplantation: infectious risk revisited

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Identification of exogenous forms of human-tropic porcine endogenous retrovirus in miniature Swine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Reappraisal of biosafety risks posed by PERVs in xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

An update on xenotransplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Selected physiologic compatibilities and incompatibilities between human and porcine organ systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Genetically engineered pigs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Xenotransplantation: where are we in 2008?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

The coagulation barrier in xenotransplantation: incompatibilities and strategies to overcome them.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Endothelial induction of fgl2 contributes to thrombosis during acute vascular xenograft rejection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Serum anti-pig antibodies as potential indicators of acute humoral xenograft rejection in pig-to-cynomolgus monkey kidney transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsiveness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Orthotopic heart transplantation in a transgenic pig-to-primate model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Administration of GAS914 in an orthotopic pig-to-baboon heart transplantation model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

Increased immunosuppression, not anticoagulation, extends cardiac xenograft survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2008.10.005

10.1016/J.TRIM.2008.10.005

7 January 2021

Identifiers

DOI

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19 August 2017

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