(Q37311022)

19 August 2017

title

The Use of In Vitro Systems for Evaluating Immunotoxicity: The Report and Recommendations of an ECVAM Workshop (English)

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19 August 2017

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6

Jaroslaw Dastych

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19 August 2017

Alessandra Gennari

1

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19 August 2017

Masarin Ban

2

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19 August 2017

Armin Braun

3

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19 August 2017

Silvia Casati

4

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19 August 2017

Emanuela Corsini

5

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19 August 2017

Jacques Descotes

7

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19 August 2017

Thomas Hartung

8

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19 August 2017

Robert Hooghe-Peters

9

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19 August 2017

Robert House

10

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19 August 2017

Marc Pallardy

11

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19 August 2017

Raymond Pieters

12

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19 August 2017

Lynnda Reid

13

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19 August 2017

Helen Tryphonas

14

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19 August 2017

Eric Tschirhart

15

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19 August 2017

Helga Tuschl

16

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19 August 2017

Rob Vandebriel

17

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19 August 2017

Laura Gribaldo

18

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19 August 2017

language of work or name

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1 April 2005

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Journal of Immunotoxicology

19 August 2017

published in

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19 August 2017

volume

2

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19 August 2017

issue

2

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19 August 2017

page(s)

61-83

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Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

19 August 2017

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1 reference

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p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene

21 January 2018

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Localization of human interleukin 13 receptor in non-haematopoietic cells

21 January 2018

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Cytokine modulation of keratinocyte cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Intolerance to nonsteroidal anti-inflammatory drugs might precede by years the onset of chronic urticaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Dendritic cells and the control of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Keratinocytes as initiators of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Assessment of immunosuppressive drug interactions: inhibition of lymphocyte function in peripheral human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration

21 January 2018

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Toll receptors modulate allergic responses: interaction with dendritic cells, T cells and mast cells

21 January 2018

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Interleukin 20: discovery, receptor identification, and role in epidermal function

21 January 2018

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Nickel and DNCB induce CCR7 expression on human dendritic cells through different signalling pathways: role of TNF-alpha and MAPK.

21 January 2018

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Is multiple chemical sensitivity a clinically defined entity?

21 January 2018

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Tumor necrosis factor-alpha production in whole blood after cardiopulmonary bypass: downregulation caused by circulating cytokine-inhibitory activities

21 January 2018

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Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: II. Meta-nitrotoluene

21 January 2018

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Activation of human dendritic cells through CD40 cross-linking.

21 January 2018

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NK-cell activity in immunotoxicity drug evaluation.

21 January 2018

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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

21 January 2018

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Origin, maturation and antigen presenting function of dendritic cells.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15476910590965832

Compared effects of morphine and nickel chloride on NK cell activity in vitro in rats and monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Epidemiology of drug allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Interleukin-13 stimulates interleukin-6 production by human keratinocytes. Similarity with interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Modulation of phenotype, cytokine production and stimulatory function of CD34+-derived DC by NiCl(2) and SDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Immunomodulating agents and hepatic drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Susceptibility to infections and immune status in Inuit infants exposed to organochlorines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Early molecular events in the induction phase of contact sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Signaling and cell death in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Effects of water-soluble cigarette smoke extracts upon the release of beta-hexosaminidase from RBL-2H3 basophilic leukaemia cells in response to substance P, compound 48/80, concanavalin A and antigen stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Primary antibody response to keyhole limpet hemocyanin in rat as a model for immunotoxicity evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Dissection of antigenic and irritative effects of epicutaneously applied haptens in mice. Evidence that not the antigenic component but nonspecific proinflammatory effects of haptens determine the concentration-dependent elicitation of allergic cont

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Effects of the cannabimimetic fatty acid derivatives 2-arachidonoylglycerol, anandamide, palmitoylethanolamide and methanandamide upon IgE-dependent antigen-induced beta-hexosaminidase, serotonin and TNF alpha release from rat RBL-2H3 basophilic leu

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Interleukin-15 is not a constitutive cytokine in the epidermis, but is inducible in culture or inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Lower levels of whole blood LPS-stimulated cytokine release are associated with poorer clinical outcomes in surgical ICU patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Mast cells as initiators of immunity and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Air Pollution and Distributions of Lymphocyte Immunophenotypes in Cord and Maternal Blood at Delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Alterations in Murine Fetal Thymus and Liver Hematopoietic Cell Populations Following Developmental Exposure to 7,12-Dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

An overview of in vitro/ex vivo assays for preclinical evaluation of immunomodulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Cytokine measurement techniques for assessing hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Innate immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Epidermal Langerhans cells are derived from cells originating in bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Anaphylaxis: a review of causes and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Infections associated with steroid use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Assessment of the allergic potential of food protein extracts and proteins on oral application using the brown Norway rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Immune biomarkers in relation to exposure to particulate matter: a cross-sectional survey in 17 cities of Central Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Nickel and skin irritants up-regulate tumor necrosis factor-alpha mRNA in keratinocytes by different but potentially synergistic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

IFN-gamma-stimulated enhancement of MHC class II antigen expression by the human mast cell line HMC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Clinical findings and immunological abnormalities in Yu-Cheng patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Risk assessment in immunotoxicology. II. Relationships between immune and host resistance tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Histamine: A mediator of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

A flow-cytometric NK-cytotoxicity assay adapted for use in rat repeated dose toxicity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

The Ah receptor recognizes DNA binding sites for the B cell transcription factor, BSAP: a possible mechanism for dioxin-mediated alteration of CD19 gene expression in human B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

The role of keratinocyte cytokines in inflammation and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Human keratinocytes constitutively produce but do not process interleukin-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Cytokine-induced autoimmune disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Enhanced expression of IL-8 in normal human keratinocytes and human keratinocyte cell line HaCaT in vitro after stimulation with contact sensitizers, tolerogens and irritants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Interleukin-10 and the interleukin-10 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Identification and induction of human keratinocyte-derived IL-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Differential IL-10 receptor gene expression in acute versus chronic atopic eczema. Modulation by immunosuppressive drugs and cytokines in normal cultured keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Human keratinocytes constitutively express interleukin-18 and secrete biologically active interleukin-18 after treatment with pro-inflammatory mediators and dinitrochlorobenzene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Respiratory involvement and immune status in yusho patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3 alpha/CCL20 by epidermal keratinocytes and its role in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Effects of contact sensitizers neomycin sulfate, benzocaine and 2,4-dinitrobenzene 1-sulfonate, sodium salt on viability, membrane integrity and IL-1 alpha mRNA expression of cultured normal human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Prevalidation of a model for predicting acute neutropenia by colony forming unit granulocyte/macrophage (CFU-GM) assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Predictive testing for autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

4. IgE, mast cells, basophils, and eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Mast cells in allergy and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Response of psoriasis to interleukin-10 is associated with suppression of cutaneous type 1 inflammation, downregulation of the epidermal interleukin-8/CXCR2 pathway and normalization of keratinocyte maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Alteration of drug biotransformation and elimination during infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Dendritic cell survival and maturation are regulated by different signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Relationship of occupation to contact dermatitis: evaluation in patients tested from 1998 to 2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

The role of mast cells in allergy and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Contaminant-induced immunotoxicity in harbour seals: wildlife at risk?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

In vitro evaluation of the sensitization potential of weak contact allergens using langerhans-like dendritic cells and autologous T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Animal models of idiosyncratic drug reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Infectious complications following renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

The role of mast cells in common gastrointestinal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Ultraviolet radiation, resistance to infectious diseases, and vaccination responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Predictive immunophenotypes: disease-related profile in chronic fatigue syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Pathways of anaphylaxis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

A review of studies on the effects of ultraviolet irradiation on the resistance to infections: evidence from rodent infection models and verification by experimental and observational human studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Critical role of mast cells in inflammatory diseases and the effect of acute stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Biology of natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Cell surface marker evaluation of infant Macaca monkey leukocytes in peripheral whole blood using simultaneous dual-color immunophenotypic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

The expression of surface markers on dendritic cells as indicators for the sensitizing potential of chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Toll-like receptors: key mediators of microbe detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

21 January 2018

Host resistance models.

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1alpha and IL-18 production by a murine and human keratinocyte cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Adverse effects of immunotherapeutics involving the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Immune-mediated side-effects of cytokines in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Immunosuppressive drugs and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Developments of immunotoxicology methods in the rat and applications to the study of environmental pollutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Tumor necrosis factor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Immunological effects of environmental exposure to polychlorinated biphenyls and dioxins in Dutch school children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

The role of natural killer cells in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

IL-4 gene expression up-regulated by mercury in rat mast cells: a role of oxidant stress in IL-4 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Allergens and irritants transcriptionally upregulate CD80 gene expression in human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

Cell Mediated Immunity induced in Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910590965832

10.1080/15476910590965832

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference