(Q37314536)

19 August 2017

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title

Structure-based antigen design: a strategy for next generation vaccines (English)

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19 August 2017

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3

Rino Rappuoli

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19 August 2017

1

Philip R Dormitzer

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19 August 2017

Jeffrey B Ulmer

2

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19 August 2017

publication date

30 October 2008

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19 August 2017

published in

Trends in Biotechnology

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19 August 2017

volume

26

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19 August 2017

issue

12

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19 August 2017

page(s)

659-667

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HIV vaccine design and the neutralizing antibody problem

19 August 2017

cites work

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12 December 2020

Antibodies to rotavirus outer capsid glycoprotein VP7 neutralize infectivity by inhibiting virion decapsidation

1 reference

12 December 2020

Antibody epitopes on the neuraminidase of a recent H3N2 influenza virus (A/Memphis/31/98).

1 reference

12 December 2020

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

1 reference

12 December 2020

Changes in the immunogenic properties of soluble gp140 human immunodeficiency virus envelope constructs upon partial deletion of the second hypervariable region

1 reference

12 December 2020

A Role for Protein Misfolding in Immunogenicity of Biopharmaceuticals

1 reference

12 December 2020

Identification of a universal Group B streptococcus vaccine by multiple genome screen

1 reference

12 December 2020

Removal of N-linked glycosylation sites in the V1 region of simian immunodeficiency virus gp120 results in redirection of B-cell responses to V3.

1 reference

12 December 2020

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

1 reference

12 December 2020

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

1 reference

12 December 2020

A dual-functional paramyxovirus F protein regulatory switch segment: activation and membrane fusion

1 reference

12 December 2020

Ribonucleic Acid Polymerase Activity Associated with Purified Calf Rotavirus

1 reference

12 December 2020

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies

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12 December 2020

Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity

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12 December 2020

Neutralizing antiviral B cell responses

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12 December 2020

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

1 reference

12 December 2020

Presentation of neutralizing epitopes by engineered rotavirus VP7's expressed by recombinant vaccinia viruses.

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12 December 2020

Structural rearrangements in the membrane penetration protein of a non-enveloped virus

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12 December 2020

Purified recombinant rotavirus VP7 forms soluble, calcium-dependent trimers

1 reference

12 December 2020

Functionally important glycosyltransferase gain and loss during catarrhine primate emergence

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12 December 2020

Antibodies to the trypsin cleavage peptide VP8 neutralize rotavirus by inhibiting binding of virions to target cells in culture

1 reference

12 December 2020

Alternative intermolecular contacts underlie the rotavirus VP5* two- to three-fold rearrangement

1 reference

12 December 2020

Penetration and uncoating of rotaviruses in cultured cells

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12 December 2020

The antigenic structure of the HIV gp120 envelope glycoprotein

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12 December 2020

The crystal structure of diphtheria toxin

1 reference

12 December 2020

The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site

1 reference

12 December 2020

Steric accessibility of the HIV-1 gp41 N-trimer region

1 reference

12 December 2020

Localization of membrane permeabilization and receptor binding sites on the VP4 hemagglutinin of rotavirus: implications for cell entry.

1 reference

12 December 2020

Tech.Sight. Phage display. Affinity selection from biological libraries

1 reference

12 December 2020

Atomic model of the papillomavirus capsid

1 reference

12 December 2020

Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation

1 reference

12 December 2020

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

12 December 2020

Structural definition of a conserved neutralization epitope on HIV-1 gp120

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12 December 2020

A unique natural human IgG antibody with anti-alpha-galactosyl specificity

1 reference

12 December 2020

Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

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12 December 2020

Relocation of antigens to the cell surface membrane can enhance immune stimulation and protection

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12 December 2020

Bridging the knowledge gaps in vaccine design

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12 December 2020

An envelope modification that renders a primary, neutralization-resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades.

1 reference

12 December 2020

High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain.

1 reference

12 December 2020

Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein

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12 December 2020

A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody

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12 December 2020

High-throughput protein production for X-ray crystallography and use of size exclusion chromatography to validate or refute computational biological unit predictions

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12 December 2020

The VR2 epitope on the PorA P1.7-2,4 protein is the major target for the immune response elicited by the strain-specific group B meningococcal vaccine MeNZB.

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12 December 2020

Immunization with baculovirus-expressed VP4 protein passively protects against simian and murine rotavirus challenge

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12 December 2020

Calcium chelation induces a conformational change in recombinant herpes simplex virus-1-expressed rotavirus VP7

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12 December 2020

Three-dimensional structure of poliovirus at 2.9 A resolution.

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12 December 2020

Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines

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12 December 2020

Structure of a neutralizing antibody bound monovalently to human rhinovirus 2

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12 December 2020

Structure of SARS coronavirus spike receptor-binding domain complexed with receptor

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12 December 2020

Carbohydrate based vaccines

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12 December 2020

Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine

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12 December 2020

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin

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12 December 2020

A role for carbohydrates in immune evasion in AIDS.

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12 December 2020

Neutralizing epitopes on herpes simplex virus-1-expressed rotavirus VP7 are dependent on coexpression of other rotavirus proteins

1 reference

12 December 2020

Increased immunogenicity of human immunodeficiency virus gp120 engineered to express Galalpha1-3Galbeta1-4GlcNAc-R epitopes

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12 December 2020

Structure of influenza virus haemagglutinin complexed with a neutralizing antibody.

1 reference

12 December 2020

Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric gp120 as Novel Antigens for HIV Vaccine Design

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12 December 2020

Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics.

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12 December 2020

Reversible inhibition of the fusion activity of measles virus F protein by an engineered intersubunit disulfide bridge.

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12 December 2020

More than one reason to rethink the use of peptides in vaccine design

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12 December 2020

Functional selection of vaccine candidate peptides from Staphylococcus aureus whole-genome expression libraries in vitro

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12 December 2020

The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes

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12 December 2020

Mutants of pertussis toxin suitable for vaccine development

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12 December 2020

Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein

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12 December 2020

Pathogenesis of dengue: challenges to molecular biology

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12 December 2020

Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein

1 reference

12 December 2020

Hepatitis B small surface antigen particles are octahedral

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12 December 2020

1 reference

12 December 2020

A universal vaccine for serogroup B meningococcus

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12 December 2020

10.1016/J.TIBTECH.2008.08.002

Identifiers

DOI

1 reference

release_jsvkm7nlojfjvmrk4xysoacrde

19 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jsvkm7nlojfjvmrk4xysoacrde

24 November 2022

mapped directly with Wikidata item

PMC publication ID

7114313

0 references

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