(Q37318403)

English

The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia

scientific article published on 09 October 2013

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia (English)

1 reference

Europe PubMed Central

19 August 2017

DNA methylation

0 references

1 reference

based on heuristic

inferred from title

author name string

Joanna Hanks

1

1 reference

Europe PubMed Central

19 August 2017

Iyeman Ayed

2

1 reference

Europe PubMed Central

19 August 2017

Neil Kukreja

3

1 reference

Europe PubMed Central

19 August 2017

Chris Rogers

4

1 reference

Europe PubMed Central

19 August 2017

Jessica Harris

5

1 reference

Europe PubMed Central

19 August 2017

Alina Gheorghiu

6

1 reference

Europe PubMed Central

19 August 2017

Chee Ling Liu

7

1 reference

Europe PubMed Central

19 August 2017

Peter Emery

8

1 reference

Europe PubMed Central

19 August 2017

Maria Pufulete

9

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

9 October 2013

1 reference

Europe PubMed Central

19 August 2017

American Journal of Clinical Nutrition

1 reference

Europe PubMed Central

19 August 2017

98

1 reference

Europe PubMed Central

19 August 2017

1564-1574

1 reference

Europe PubMed Central

19 August 2017

6

1 reference

Europe PubMed Central

19 August 2017

B vitamin intakes and incidence of colorectal cancer: results from the Women's Health Initiative Observational Study cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Metabolic, hormonal and immunological associations with global DNA methylation among postmenopausal women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

High levels of folate from supplements and fortification are not associated with increased risk of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

The association between first trimester micronutrient intake, MTHFR genotypes, and global DNA methylation in pregnant women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Pooled analyses of 13 prospective cohort studies on folate intake and colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Epigenetics in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

The MTHFR 677TT genotype and folate intake interact to lower global leukocyte DNA methylation in young Mexican American women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Folic Acid for the Prevention of Colorectal Adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

MGMT promoter methylation and field defect in sporadic colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Folate intake and colorectal cancer risk: a meta-analytical approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

CpG island methylator phenotype in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

6 September 2017

Methylation of the ESR1 CpG island in the colorectal mucosa is an 'all or nothing' process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

14 September 2017

Aspirin and folic acid for the prevention of recurrent colorectal adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

26 June 2018

Low colonocyte folate is associated with uracil misincorporation and global DNA hypomethylation in human colorectum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Association of dietary and genetic factors related to one-carbon metabolism with global methylation level of leukocyte DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Methylenetetrahydrofolate Reductase 677C→T Variant Modulates Folate Status Response to Controlled Folate Intakes in Young Women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Validation of a short food frequency questionnaire to assess folate intake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Colonic mucosal concentrations of folate are accurately predicted by blood measurements of folate status among individuals ingesting physiologic quantities of folate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Accelerated age-related CpG island methylation in ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Folate supplementation and adenomatous colonic polyps.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

2 September 2018

Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831541

3 December 2018

CpG island methylator phenotype in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the methylenetetrahydrofolate reductase 677C-->T mutation on the relations among folate intake and plasma folate and homocysteine concentrations in a general population sample

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: correlation with nutrient intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypomethylation of DNA from benign and malignant human colon neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related hypermethylation of the 5' region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global DNA methylation measured by liquid chromatography-tandem mass spectrometry: analytical technique, reference values and determinants in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/24108782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3945/AJCN.113.061432

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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