(Q37323204)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

title

Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Wei Dai

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Josephine Ko

4

1 reference

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23 March 2020

Wai Tong Ng

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Ka On Lam

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Maria Li Lung

23

1 reference

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23 March 2020

7

Merrin Man Long Leong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Roger Kai-Cheong Ngan

14

object named as

Roger Kai Cheong Ngan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

11

Dora Lai-Wan Kwong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

12

Anne Wing-Mui Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

17

Victor Ho-Fun Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Arthur Kwok Leung Cheung

3

object named as

Arthur Kwok Leung Cheung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

6

Bonnie Wing Yan Wong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

15

Chun Chung Yau

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

16

Stewart Tung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

author name string

Rebecca Kan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Mingdan Deng

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Tommy Chin Tung Kwok

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Jimmy Yu-Wai Chan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Chung Kong Kwan

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Wing Sum Li

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Stephen Yau

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Kwok-Wah Chan

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

language of work or name

English

0 references

publication date

19 September 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

volume

113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

page(s)

11283-11288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma

23 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Nasopharyngeal Cancer: Molecular Landscape

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Integrated genomic analysis suggests MLL3 is a novel candidate susceptibility gene for familial nasopharyngeal carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Second-generation PLINK: rising to the challenge of larger and richer datasets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Comprehensive genomic characterization of head and neck squamous cell carcinomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Comprehensive molecular characterization of gastric adenocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

The genomic landscape of nasopharyngeal carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Signatures of mutational processes in human cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Mutational heterogeneity in cancer and the search for new cancer-associated genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Molecular basis of NF-κB signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Detecting false-positive signals in exome sequencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

A framework for variation discovery and genotyping using next-generation DNA sequencing data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

CYLD: a deubiquitination enzyme with multiple roles in cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

A20: from ubiquitin editing to tumour suppression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Fast and accurate short read alignment with Burrows-Wheeler transform

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

PLINK: a tool set for whole-genome association and population-based linkage analyses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Epstein-barr virus-associated malignancies: epidemiologic patterns and etiologic implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Structure of an IkappaBalpha/NF-kappaB complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

6 September 2017

CR2 complement receptor

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

6 September 2017

https://api.crossref.org/works/10.1073%2FPNAS.1607606113

Absence of p53 gene mutations in primary nasopharyngeal carcinomas

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

The impact of Epstein-Barr virus status on clinical outcome in diffuse large B-cell lymphoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5056105

Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue

2 September 2018

1 reference

12 December 2020

Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization

1 reference

12 December 2020

Comparative genomic hybridization analysis of nasopharygeal carcinoma: consistent patterns of genetic aberrations and clinicopathological correlations

1 reference

12 December 2020

Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1607606113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27647909%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

PubMed publication ID

27647909

1 reference