(Q37323439)

19 August 2017

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title

The impact of transgenic IGF-IR overexpression on mammary development and tumorigenesis (English)

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19 August 2017

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Robert A Jones

1

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19 August 2017

Roger A Moorehead

series ordinal

2

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19 August 2017

publication date

11 November 2008

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Journal of Mammary Gland Biology and Neoplasia

19 August 2017

published in

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19 August 2017

volume

13

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19 August 2017

issue

4

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19 August 2017

page(s)

407-413

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Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

19 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10911-008-9097-1

Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10911-008-9097-1

Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations

21 January 2018

1 reference

12 December 2020

Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

1 reference

12 December 2020

Transitions between epithelial and mesenchymal states in development and disease

1 reference

12 December 2020

Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds

1 reference

12 December 2020

Overexpression of des(1-3) insulin-like growth factor 1 in the mammary glands of transgenic mice delays the loss of milk production with prolonged lactation

1 reference

12 December 2020

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

12 December 2020

Expression of insulin-like growth factor-I receptor, estrogen receptor alpha, Bcl-2 and Bax proteins in human breast cancer

1 reference

12 December 2020

Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor.

1 reference

12 December 2020

Transgenic hypersecretion of des(1-3) human insulin-like growth factor I in mouse milk has limited effects on the gastrointestinal tract in suckling pups

1 reference

12 December 2020

Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer.

1 reference

12 December 2020

A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology

1 reference

12 December 2020

Protective effects of pregnancy and lactation against N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats.

1 reference

12 December 2020

Increased Milk Yield in Transgenic Mice Expressing Insulin-like Growth Factor 1

1 reference

12 December 2020

Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation

1 reference

12 December 2020

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

1 reference

12 December 2020

P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland

1 reference

12 December 2020

Insulin-like growth factors and breast cancer

1 reference

12 December 2020

Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo

1 reference

12 December 2020

Type I insulin-like growth factor receptor function in breast cancer.

1 reference

12 December 2020

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

1 reference

12 December 2020

Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

1 reference

12 December 2020

Reversibility and recurrence of IGF-IR-induced mammary tumors

1 reference

12 December 2020

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

1 reference

12 December 2020

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

12 December 2020

Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin

1 reference

12 December 2020

Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis

1 reference

12 December 2020

Inability of overexpressed des(1-3)human insulin-like growth factor I (IGF-I) to inhibit forced mammary gland involution is associated with decreased expression of IGF signaling molecules

1 reference

12 December 2020

Expression of ovine insulin-like growth factor-1 (IGF-1) stimulates alveolar bud development in mammary glands of transgenic mice

1 reference

12 December 2020

The insulin-like growth factor system in advanced breast cancer

1 reference

12 December 2020

Ductal growth is impeded in mammary glands of C-neu transgenic mice.

1 reference

12 December 2020

Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis

1 reference

12 December 2020

Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model

1 reference

12 December 2020

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

1 reference

12 December 2020

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1 reference

12 December 2020

Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail

1 reference

12 December 2020

Metastasizing mammary carcinomas in H19 enhancers-Igf2 transgenic mice

1 reference

12 December 2020

Breast cancer incidence among atomic bomb survivors, Hiroshima and Nagasaki, 1950-69

1 reference

12 December 2020

ErbB2 is required for ductal morphogenesis of the mammary gland

1 reference

12 December 2020

Inhibition of mammary epithelial apoptosis and sustained phosphorylation of Akt/PKB in MMTV-IGF-II transgenic mice

1 reference

12 December 2020

Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

1 reference

12 December 2020

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression

1 reference

12 December 2020

Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation

1 reference

12 December 2020

IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition

1 reference

12 December 2020

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

12 December 2020

Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: studies in transgenic mice

1 reference

12 December 2020

The protective role of pregnancy in breast cancer

1 reference

12 December 2020

The transcriptional repressor Snail promotes mammary tumor recurrence

1 reference

12 December 2020

The IGF-I receptor in mitogenesis and transformation of mouse embryo cells: role of receptor number

1 reference

12 December 2020

Type I insulin-like growth factor receptor over-expression induces proliferation and anti-apoptotic signaling in a three-dimensional culture model of breast epithelial cells

1 reference

12 December 2020

Epithelial-mesenchymal transitions in tumour progression

1 reference

12 December 2020

10.1007/S10911-008-9097-1

Identifiers

DOI

1 reference

release_bpbrbp4ea5gfljtun7nzu7bwzu

19 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bpbrbp4ea5gfljtun7nzu7bwzu

24 November 2022

mapped directly with Wikidata item

1 reference