(Q42738098)

English

Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail

scientific article published on 12 February 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail (English)

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

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author name string

Hyun-Jung Kim

1

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Beate C Litzenburger

2

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Xiaojiang Cui

3

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

David A Delgado

4

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Brian C Grabiner

5

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Xin Lin

6

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Michael T Lewis

7

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Marco M Gottardis

8

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Tai W Wong

9

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Ricardo M Attar

10

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Joan M Carboni

11

1 reference

Europe PubMed Central

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6 November 2017

Adrian V Lee

12

1 reference

Europe PubMed Central

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6 November 2017

language of work or name

0 references

publication date

12 February 2007

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

27

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

8

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

3165-3175

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

1 reference

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27 May 2018

Inhibitors of insulin-like growth factor signaling: a therapeutic approach for breast cancer

1 reference

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The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas.

1 reference

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27 May 2018

Type I insulin-like growth factor receptor over-expression induces proliferation and anti-apoptotic signaling in a three-dimensional culture model of breast epithelial cells

1 reference

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AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

1 reference

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27 May 2018

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

1 reference

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27 May 2018

The transcriptional repressor Snail promotes mammary tumor recurrence

1 reference

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Modelling glandular epithelial cancers in three-dimensional cultures

1 reference

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Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

1 reference

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Lipoxin A4 modifies platelet-derived growth factor-induced pro-fibrotic gene expression in human renal mesangial cells

1 reference

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27 May 2018

TGF-beta and epithelial-to-mesenchymal transitions

1 reference

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27 May 2018

Molecular requirements for epithelial-mesenchymal transition during tumor progression

1 reference

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27 May 2018

Mammary epithelial cell transformation: insights from cell culture and mouse models

1 reference

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27 May 2018

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

1 reference

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27 May 2018

Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

1 reference

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27 May 2018

Unraveling signalling cascades for the Snail family of transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Oncogenic transformation of human mammary epithelial cells by autocrine human growth hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Involvement of insulin receptor substrate 2 in mammary tumor metastasis

1 reference

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27 May 2018

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Effects of herbal compound 861 on human hepatic stellate cell proliferation and activation

1 reference

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27 May 2018

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Epithelial-mesenchymal transitions in development and pathologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.

1 reference

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27 May 2018

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer

1 reference

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A requirement for CARMA1 in TCR-induced NF-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

NF-kappaB as a therapeutic target in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899918

27 May 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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Induction and regulation of epithelial-mesenchymal transitions

1 reference

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27 May 2018

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

1 reference

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27 May 2018

Function of the IGF-I receptor in breast cancer

1 reference

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27 May 2018

The IGF-I receptor in cancer research

1 reference

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Invasive phenotype of MCF10A cells overexpressing c-Ha-ras and c-erbB-2 oncogenes.

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An overview of epithelio-mesenchymal transformation

1 reference

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

1 reference

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27 May 2018

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

1 reference

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Transcriptional repressor snail and progression of human hepatocellular carcinoma

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Transforming growth factor-beta and epidermal growth factor synergistically stimulate epithelial to mesenchymal transition (EMT) through a MEK-dependent mechanism in primary cultured pig thyrocytes.

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Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

1 reference

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16 August 2018

Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds

1 reference

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16 August 2018

EphA2 overexpression causes tumorigenesis of mammary epithelial cells.

1 reference

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The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK, Cas, and paxillin.

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The role of the insulin-like growth factor I receptor in transformation and apoptosis

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Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17296734

12 December 2020

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IGF-1: old growth factor shines as new drug target

1 reference

https://pubmed.ncbi.nlm.nih.gov/17296734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/17296734

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based on heuristic

inferred from PubMed ID database lookup

Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17296734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.01315-06

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

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