(Q37324303)

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Genetically modified T cells targeting interleukin-11 receptor α-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases

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Europe PubMed Central

PMC publication ID

19 August 2017

Genetically modified T cells targeting interleukin-11 receptor α-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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Helen Huls

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Europe PubMed Central

PMC publication ID

19 August 2017

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Gangxiong Huang

1

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Europe PubMed Central

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19 August 2017

Ling Yu

2

1 reference

Europe PubMed Central

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19 August 2017

Laurence Jn Cooper

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Mario Hollomon

4

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Europe PubMed Central

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19 August 2017

Eugenie S Kleinerman

6

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Europe PubMed Central

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19 August 2017

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publication date

10 November 2011

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Europe PubMed Central

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19 August 2017

Cancer Research

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Europe PubMed Central

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19 August 2017

72

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Europe PubMed Central

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19 August 2017

1

1 reference

Europe PubMed Central

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19 August 2017

271-281

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.

1 reference

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6 September 2017

Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature

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Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor

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The role of Fas/FasL in the metastatic potential of osteosarcoma and targeting this pathway for the treatment of osteosarcoma lung metastases

1 reference

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6 September 2017

Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression.

1 reference

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6 September 2017

The interleukin-11 receptor alpha as a candidate ligand-directed target in osteosarcoma: consistent data from cell lines, orthotopic models, and human tumor samples

1 reference

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Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

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Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group

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Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine

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Adoptive T cell therapy for cancer in the clinic

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Gene splicing and mutagenesis by PCR-driven overlap extension

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Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells

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Expression of interleukin 11 and its receptor and their prognostic value in human breast cancer

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Development and application of CD19-specific T cells for adoptive immunotherapy of B cell malignancies

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Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer

1 reference

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Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells

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Steps toward mapping the human vasculature by phage display.

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Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma

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Hematopoietic, immunomodulatory and epithelial effects of interleukin-11.

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Effect of interleukin 11 on normal and pathological thrombopoiesis

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Efficacy of liposomal muramyl tripeptide (CGP 19835A) in the treatment of relapsed osteosarcoma

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Interleukin-6 family of cytokines and gp130

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R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts

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Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

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Fas-negative osteosarcoma tumor cells are selected during metastasis to the lungs: the role of the Fas pathway in the metastatic process of osteosarcoma

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A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies

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Development of a novel spontaneous metastasis model of human osteosarcoma transplanted orthotopically into bone of athymic mice

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Adjuvant chemotherapy for osteosarcoma: a randomized prospective trial

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Prognostic significance of early lymphocyte recovery in pediatric osteosarcoma.

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A new optical and nuclear dual-labeled imaging agent targeting interleukin 11 receptor alpha-chain.

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Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy

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Activation of tumoricidal properties in human blood monocytes by liposomes containing lipophilic muramyl tripeptide

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Identifiers

10.1158/0008-5472.CAN-11-2778

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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