(Q37325331)

English

A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced pancreatic ductal adenocarcinoma

scientific article published on 27 August 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced pancreatic ductal adenocarcinoma (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

0 references

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inferred from title

1 reference

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monoclonal antibody

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based on heuristic

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Gregory L Beatty

object named as

Gregory L Beatty

1

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object named as

Babak Saboury

4

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Andrea B. Troxel

object named as

Andrea B Troxel

7

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6

object named as

Abass Alavi

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Drew A Torigian

2

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Europe PubMed Central

PMC publication ID

19 August 2017

E Gabriela Chiorean

3

1 reference

Europe PubMed Central

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19 August 2017

Alex Brothers

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Weijing Sun

8

1 reference

Europe PubMed Central

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19 August 2017

Ursina R Teitelbaum

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Robert H Vonderheide

10

1 reference

Europe PubMed Central

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19 August 2017

Peter J O'Dwyer

11

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Europe PubMed Central

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19 August 2017

language of work or name

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publication date

27 August 2013

1 reference

Europe PubMed Central

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19 August 2017

Clinical Cancer Research

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Europe PubMed Central

PMC publication ID

19 August 2017

19

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19 August 2017

22

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Europe PubMed Central

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19 August 2017

6286-6295

1 reference

Europe PubMed Central

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19 August 2017

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

(18)F-FDG PET/CT for monitoring treatment responses to the epidermal growth factor receptor inhibitor erlotinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Molecular mechanism and function of CD40/CD40L engagement in the immune system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

FDG-PET in the prediction of survival of patients with cancer of the pancreas: a pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations. European Organization for Research and Treatment of Cancer (EORTC) PET Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

6 September 2017

PET to assess early metabolic response and to guide treatment of adenocarcinoma of the oesophagogastric junction: the MUNICON phase II trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

14 September 2017

Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

14 September 2017

Clinically meaningful responses to sequential gemcitabine-based chemotherapy regimens in a patient with metastatic pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

Feasibility and performance of novel software to quantify metabolically active volumes and 3D partial volume corrected SUV and metabolic volumetric products of spinal bone marrow metastases on 18F-FDG-PET/CT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

Modalities for evaluating chemotherapeutic efficacy and survival time in patients with advanced pancreatic cancer: comparison between FDG-PET, CT, and serum tumor markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

2 September 2018

CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834036

3 December 2018

Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40

1 reference

https://pubmed.ncbi.nlm.nih.gov/23983255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of the immune reaction to pancreatic cancer from inception to invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23983255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help

1 reference

https://pubmed.ncbi.nlm.nih.gov/23983255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of M2-polarized tumor-associated macrophage in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23983255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD40 agonist antibody CP-870,893 enhances dendritic cell and B-cell activity and promotes anti-tumor efficacy in SCID-hu mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23983255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy and chemotherapy--a practical partnership

1 reference

https://pubmed.ncbi.nlm.nih.gov/23983255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-13-1320

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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