(Q37333773)

19 August 2017

Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1. (English)

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19 August 2017

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1 reference

Sulagna Banerjee

1

1 reference

19 August 2017

Veena Sangwan

2

1 reference

19 August 2017

Olivia McGinn

3

1 reference

19 August 2017

Rohit Chugh

4

1 reference

19 August 2017

Vikas Dudeja

5

1 reference

19 August 2017

Selwyn M Vickers

6

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19 August 2017

Ashok K Saluja

7

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19 August 2017

language of work or name

English

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publication date

15 October 2013

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Journal of Biological Chemistry

19 August 2017

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19 August 2017

288

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19 August 2017

47

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19 August 2017

33927-33938

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describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3837133/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity

6 September 2017

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A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

6 September 2017

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MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization

6 September 2017

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Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis

6 September 2017

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Gene expression of O-GlcNAc cycling enzymes in human breast cancers

6 September 2017

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XPB, a subunit of TFIIH, is a target of the natural product triptolide.

6 September 2017

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6 September 2017

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Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation

6 September 2017

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Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways

6 September 2017

1 reference

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Modulation of transcription factor function by O-GlcNAc modification

6 September 2017

1 reference

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Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms

6 September 2017

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Cell signaling, the essential role of O-GlcNAc!

6 September 2017

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Sp transcription factor family and its role in cancer

6 September 2017

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Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin

6 September 2017

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Mammalian SP/KLF transcription factors: bring in the family

6 September 2017

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Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1

6 September 2017

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Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

A developmentally regulated GAGA box-binding factor and Sp1 are required for transcription of the hsp70.1 gene at the onset of mouse zygotic genome activation.

6 September 2017

1 reference

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Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expression

6 September 2017

1 reference

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Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation

6 September 2017

1 reference

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O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3k/Akt/NF-kappaB pathways in human multiple myeloma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Expression profiles of a human pancreatic cancer cell line upon induction of apoptosis search for modulators in cancer therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Triptolide inhibits the growth and metastasis of solid tumors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Antitumor activity of triptolide against cholangiocarcinoma growth in vitro and in hamsters

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Post-translational modification by O-GlcNAc: another way to change protein function.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Discovery of O-GlcNAc transferase inhibitors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837133

Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer

2 September 2018

1 reference

12 December 2020

Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

1 reference

12 December 2020

Sp1, a new biomarker that identifies a subset of aggressive pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M113.500983

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

24129563

1 reference