(Q37335774)

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Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.

scientific article published on 30 September 2013

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23 February 2020

Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses (English)

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23 February 2020

Plasmodium falciparum

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Abdirahman Abdi

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23 February 2020

Lynette Isabella Ochola-Oyier

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23 February 2020

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Alexis Nzila

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23 February 2020

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Leah Mwai

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23 February 2020

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John Okombo

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23 February 2020

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Lewa Pole

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23 February 2020

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Steven M Kiara

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23 February 2020

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Colin J Sutherland

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23 February 2020

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30 September 2013

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23 February 2020

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Antimicrobial Agents and Chemotherapy

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23 February 2020

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23 February 2020

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23 February 2020

6196-6204

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23 February 2020

Global analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine

1 reference

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The polymorphic linker domain of pfmdr1 is associated with resistance-conferring mutations in Plasmodium falciparum populations from East and West Africa

1 reference

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Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

1 reference

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6 September 2017

In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes

1 reference

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Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana

1 reference

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6 September 2017

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

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6 September 2017

A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial

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6 September 2017

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients

1 reference

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6 September 2017

Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance

1 reference

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6 September 2017

Increased polymorphism near low-complexity sequences across the genomes of Plasmodium falciparum isolates

1 reference

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6 September 2017

Artesunate tolerance in transgenic Plasmodium falciparum parasites overexpressing a tryptophan-rich protein

1 reference

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6 September 2017

Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression

1 reference

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6 September 2017

Association of microsatellite variations of Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene with reduced in vitro susceptibility to quinine: lack of confirmation in clinical isolates from Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837885

6 September 2017

Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome

1 reference

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6 September 2017

Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837885

6 September 2017

Artemisinin Resistance in Plasmodium falciparum Malaria

1 reference

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6 September 2017

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

1 reference

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6 September 2017

A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies.

1 reference

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6 September 2017

Advances in understanding the genetic basis of antimalarial drug resistance

1 reference

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6 September 2017

Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites

1 reference

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6 September 2017

A systematic map of genetic variation in Plasmodium falciparum

1 reference

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6 September 2017

Recombination hotspots and population structure in Plasmodium falciparum

1 reference

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6 September 2017

Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance?

1 reference

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6 September 2017

Short report: Rapid DNA extraction from archive blood spots on filter paper for genotyping of Plasmodium falciparum.

1 reference

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6 September 2017

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

1 reference

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6 September 2017

Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae

1 reference

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6 September 2017

Merozoite surface protein 8 of Plasmodium falciparum contains two epidermal growth factor-like domains

1 reference

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6 September 2017

The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin

1 reference

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6 September 2017

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

1 reference

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6 September 2017

High recombination rate in natural populations of Plasmodium falciparum

1 reference

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6 September 2017

Analysis of compositionally biased regions in sequence databases

1 reference

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6 September 2017

Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from subsaharan Africa

1 reference

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6 September 2017

Non-globular domains in protein sequences: automated segmentation using complexity measures

1 reference

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6 September 2017

Antigens with repeated amino acid sequences from the asexual blood stages of Plasmodium falciparum

1 reference

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6 September 2017

Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand

1 reference

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1 reference

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14 September 2017

Drug resistance and the P-glycoprotein homologues of Plasmodium falciparum

1 reference

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In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya

1 reference

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26 June 2018

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

1 reference

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26 June 2018

Functional role of the linker region in purified human P-glycoprotein.

1 reference

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26 June 2018

Multiple transporters associated with malaria parasite responses to chloroquine and quinine

1 reference

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Multidrug transporters from bacteria to man: similarities in structure and function

1 reference

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26 June 2018

The linker region of the ABC-transporter Ste6 mediates ubiquitination and fast turnover of the protein

1 reference

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26 June 2018

On the abundance, amino acid composition, and evolutionary dynamics of low-complexity regions in proteins

1 reference

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Proline-induced distortions of transmembrane helices.

1 reference

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2 September 2018

The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum

1 reference

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2 September 2018

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10.1128/AAC.01465-13

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23 February 2020

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23 February 2020

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23 February 2020

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