(Q37336728)

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A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition.

scientific article published on 09 October 2013

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scholarly article

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27 February 2020

A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition (English)

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27 February 2020

Bernard Heymann

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27 February 2020

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Eric O Freed

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27 February 2020

author name string

Paul W Keller

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27 February 2020

Rick K Huang

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27 February 2020

Matthew R England

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27 February 2020

Kayoko Waki

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27 February 2020

Naiqian Cheng

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27 February 2020

Rebecca C Craven

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27 February 2020

Alasdair C Steven

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27 February 2020

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9 October 2013

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27 February 2020

Journal of Virology

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27 February 2020

87

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27 February 2020

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27 February 2020

13655-13664

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27 February 2020

Structural and functional insights into the HIV-1 maturation inhibitor binding pocket

1 reference

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6 September 2017

Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid

1 reference

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6 September 2017

Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy

1 reference

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6 September 2017

Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease

1 reference

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6 September 2017

The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles

1 reference

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6 September 2017

Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres

1 reference

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6 September 2017

On the role of the SP1 domain in HIV-1 particle assembly: a molecular switch?

1 reference

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6 September 2017

Atomic-level modelling of the HIV capsid

1 reference

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6 September 2017

Structural analysis of HIV-1 maturation using cryo-electron tomography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

HIV-1 maturation inhibitor bevirimat stabilizes the immature Gag lattice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

1 reference

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6 September 2017

New small-molecule inhibitor class targeting human immunodeficiency virus type 1 virion maturation

1 reference

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6 September 2017

Structure and assembly of immature HIV

1 reference

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6 September 2017

Virus maturation as a new HIV-1 therapeutic target

1 reference

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6 September 2017

NMR structure of the N-terminal domain of capsid protein from the mason-pfizer monkey virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

X-ray structures of the hexameric building block of the HIV capsid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

Visualization of a missing link in retrovirus capsid assembly

1 reference

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6 September 2017

Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

The structural biology of HIV assembly

1 reference

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6 September 2017

Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

Structure of full-length HIV-1 CA: a model for the mature capsid lattice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

Computational resources for cryo-electron tomography in Bsoft.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

Human immunodeficiency virus type 1 assembly, release, and maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells

1 reference

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6 September 2017

Bsoft: image processing and molecular modeling for electron microscopy

1 reference

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6 September 2017

The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

1 reference

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6 September 2017

Helical structure determined by NMR of the HIV-1 (345-392)Gag sequence, surrounding p2: implications for particle assembly and RNA packaging

1 reference

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6 September 2017

High-resolution structure of a retroviral capsid hexameric amino-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838239

6 September 2017

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

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6 September 2017

The stoichiometry of Gag protein in HIV-1.

1 reference

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6 September 2017

Small-molecule inhibition of human immunodeficiency virus type 1 replication by specific targeting of the final step of virion maturation

1 reference

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6 September 2017

PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing

1 reference

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6 September 2017

Structure and self-association of the Rous sarcoma virus capsid protein

1 reference

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6 September 2017

Solution structure and dynamics of the Rous sarcoma virus capsid protein and comparison with capsid proteins of other retroviruses

1 reference

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6 September 2017

Inhibitors of HIV-1 protease: a major success of structure-assisted drug design

1 reference

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6 September 2017

A putative alpha-helical structure which overlaps the capsid-p2 boundary in the human immunodeficiency virus type 1 Gag precursor is crucial for viral particle assembly

1 reference

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6 September 2017

Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein

1 reference

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6 September 2017

Topological mechanisms involved in the formation of clathrin-coated vesicles

1 reference

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p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease

1 reference

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6 September 2017

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

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6 September 2017

Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites.

1 reference

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14 September 2017

Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding

1 reference

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14 September 2017

Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles

1 reference

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14 September 2017

Assembly properties of the human immunodeficiency virus type 1 CA protein

1 reference

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14 September 2017

The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions.

1 reference

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14 September 2017

The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity

1 reference

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14 September 2017

Retroviral capsid assembly: a role for the CA dimer in initiation

1 reference

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28 September 2017

Hydrogen/deuterium exchange analysis of HIV-1 capsid assembly and maturation

1 reference

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26 June 2018

Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.

1 reference

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26 June 2018

Image reconstructions of helical assemblies of the HIV-1 CA protein

1 reference

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26 June 2018

HIV-1 gag proteins: diverse functions in the virus life cycle

1 reference

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26 June 2018

Proteolytic cleavage and structural transformation: Their relationship in bacteriophage T4 capsid maturation

1 reference

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26 June 2018

A resolution criterion for electron tomography based on cross-validation.

1 reference

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2 September 2018

Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange.

1 reference

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2 September 2018

Assembly and analysis of conical models for the HIV-1 core.

1 reference

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2 September 2018

Identifiers

10.1128/JVI.01408-13

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24109217%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

Europe PubMed Central

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27 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24109217%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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