(Q37341007)

19 August 2017

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title

FAK expression regulation and therapeutic potential (English)

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19 August 2017

Shufeng Li

1

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19 August 2017

Zi-Chun Hua

series ordinal

2

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19 August 2017

publication date

1 January 2008

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Advances in Cancer Research

19 August 2017

published in

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19 August 2017

volume

101

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19 August 2017

page(s)

45-61

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Regulation of focal adhesion kinase by a novel protein inhibitor FIP200

19 August 2017

cites work

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7 January 2021

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

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7 January 2021

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Interaction of focal adhesion kinase with cytoskeletal protein talin

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7 January 2021

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

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7 January 2021

Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2.

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7 January 2021

Disruption of focal adhesion kinase slows transendothelial migration of AU-565 breast cancer cells

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7 January 2021

Control of adhesion-dependent cell survival by focal adhesion kinase

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7 January 2021

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

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7 January 2021

Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites

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7 January 2021

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

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7 January 2021

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

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p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

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7 January 2021

v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion

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7 January 2021

FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

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7 January 2021

Differential regulation of cell motility and invasion by FAK

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7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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7 January 2021

Synergistic induction of monocyte chemoattractant protein-1 by integrins and platelet-derived growth factor via focal adhesion kinase in mesangial cells

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7 January 2021

Focal adhesion kinase expression in oral cancers

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7 January 2021

Focal adhesion kinase and its potential involvement in tumor invasion and metastasis

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7 January 2021

Polyethylenimine-complexed plasmid particles targeting focal adhesion kinase function as melanoma tumor therapeutics

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7 January 2021

The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly

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7 January 2021

Negative regulation of FAK signaling by SOCS proteins

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7 January 2021

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18

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7 January 2021

FAK signaling in neoplastic disorders: a linkage between inflammation and cancer

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7 January 2021

The expression and tyrosine phosphorylation of E-cadherin/catenin adhesion complex, and focal adhesion kinase in invasive cervical carcinomas

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7 January 2021

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

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7 January 2021

The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase

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7 January 2021

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

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7 January 2021

Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

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7 January 2021

The focal adhesion kinase

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7 January 2021

Paxillin: a focal adhesion-associated adaptor protein

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7 January 2021

Focal adhesion kinase and associated proteins

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7 January 2021

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

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7 January 2021

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

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7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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7 January 2021

Ets target genes: past, present and future

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7 January 2021

A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth

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7 January 2021

Cellular characterization of a novel focal adhesion kinase inhibitor

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7 January 2021

FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

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7 January 2021

Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.

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7 January 2021

Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion

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7 January 2021

Differentiation and transforming growth factor-beta receptor down-regulation by collagen-alpha2beta1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells

1 reference

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7 January 2021

Characterization of graf, the GTPase-activating protein for rho associated with focal adhesion kinase. Phosphorylation and possible regulation by mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Paxillin and focal adhesion signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Suppression of Pyk2 kinase and cellular activities by FIP200

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Focal adhesion kinase: a potential target in cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

FAK overexpression upregulates cyclin D3 and enhances cell proliferation via the PKC and PI3-kinase-Akt pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Regulation of the cell cycle by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900403-X

7 January 2021

Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression

1 reference

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7 January 2021

10.1016/S0065-230X(08)00403-X

Identifiers

DOI

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19 August 2017

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