(Q37342855)

English

CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

scientific article published on 21 October 2013

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19 August 2017

CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice (English)

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19 August 2017

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photoreceptor protein

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Florian Sennlaub

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Emeline Nandrot

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Jean-Louis Bourges

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Shulong J Hu

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Elisa Dominguez

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Elodie Guyon

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Noah Saederup

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Israel F Charo

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EMBO Molecular Medicine

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1775-1793

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2 June 2020

Macrophage biology in development, homeostasis and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood

1 reference

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6 September 2017

The role of microglia in the healthy brain.

1 reference

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6 September 2017

Studying the mononuclear phagocyte system in the molecular age.

1 reference

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6 September 2017

Dysregulation in retinal para-inflammation and age-related retinal degeneration in CCL2 or CCR2 deficient mice.

1 reference

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6 September 2017

A review and meta-analysis of the association between C-reactive protein and age-related macular degeneration

1 reference

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6 September 2017

The myeloid cells of the central nervous system parenchyma

1 reference

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6 September 2017

Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases.

1 reference

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6 September 2017

Development of monocytes, macrophages, and dendritic cells

1 reference

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6 September 2017

Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

6 September 2017

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

1 reference

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6 September 2017

Inhibition of laser-induced choroidal neovascularization by atorvastatin by downregulation of monocyte chemotactic protein-1 synthesis in mice

1 reference

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6 September 2017

Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

1 reference

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6 September 2017

Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

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1 reference

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1 reference

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Complement factor H polymorphism and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840491

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Complement factor H variant increases the risk of age-related macular degeneration

1 reference

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The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration

1 reference

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The epidemiology of age-related macular degeneration

1 reference

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1 reference

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1 reference

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1 reference

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26 June 2018

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26 June 2018

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2 September 2018

Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa.

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2 September 2018

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2 September 2018

Polymorphisms in CFH, HTRA1 and CX3CR1 confer risk to exudative age-related macular degeneration in Han Chinese

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2 September 2018

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2 September 2018

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2 September 2018

Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice.

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2 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of geographic atrophy of the retinal pigment epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/24142887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization

1 reference

https://pubmed.ncbi.nlm.nih.gov/24142887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripherin. A rim-specific membrane protein of rod outer segment discs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24142887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ccl2/Cx3cr1 Knockout Mice Have Inner Retinal Dysfunction but Are Not an Accelerated Model of AMD

1 reference

https://pubmed.ncbi.nlm.nih.gov/24142887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of sequence variation in the CX3CR1 gene with geographic atrophy age-related macular degeneration in a Greek population

1 reference

https://pubmed.ncbi.nlm.nih.gov/24142887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fifteen-Year Cumulative Incidence of Age-Related Macular Degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24142887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/EMMM.201302692

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24142887%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24142887%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24142887%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

ResearchGate publication ID

0 references

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