(Q37346219)

19 August 2017

1 reference

title

DNA methylation and cancer pathways in gastrointestinal tumors (English)

1 reference

19 August 2017

0 references

1

Hiromu Suzuki

1 reference

19 August 2017

4

Kohzoh Imai

1 reference

19 August 2017

3

Yasuhisa Shinomura

1 reference

19 August 2017

5

Minoru Toyota

1 reference

19 August 2017

Takashi Tokino

2

1 reference

19 August 2017

1 December 2008

1 reference

19 August 2017

1 reference

19 August 2017

9

1 reference

19 August 2017

12

1 reference

19 August 2017

1917-1928

1 reference

Lessons from hereditary colorectal cancer

19 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

CpG island methylation in gastroenterologic neoplasia: a maturing field.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Worms gang up on bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The history of cancer epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

DNA hypomethylation leads to elevated mutation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Cancer epigenomics: DNA methylomes and histone-modification maps

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Cancer genes and the pathways they control

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The consensus coding sequences of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The genomic landscapes of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

WNT and beta-catenin signalling: diseases and therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Morphogenetic roles of classic cadherins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

APC, signal transduction and genetic instability in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Convergence of Wnt, beta-catenin, and cadherin pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

E-cadherin germline mutations in familial gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Secreted antagonists of the Wnt signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Secreted Frizzled-related proteins: searching for relationships and patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Function and biological roles of the Dickkopf family of Wnt modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Control of gut differentiation and intestinal-type gastric carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

RAS oncogenes: the first 30 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

BRAF as a potential therapeutic target in melanoma and other malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Suppressing cancer: the importance of being senescent.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Oncogene-induced cell senescence--halting on the road to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

RASSF6 is a novel member of the RASSF family of tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Identification of RASSF8 as a candidate lung tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Genetic and epigenetic profiling in early colorectal tumors and prediction of invasive potential in pT1 (early invasive) colorectal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Alterations and hypermethylation of the p14(ARF) gene in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Oncomirs - microRNAs with a role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

A microRNA component of the p53 tumour suppressor network

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

A microRNA DNA methylation signature for human cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Intratumoral hypoxia, radiation resistance, and HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Physiological and pathological responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Chromosome segregation and cancer: cutting through the mystery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic inactivation of CHFR in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Targeting polo-like kinase 1 for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Chfr is required for tumor suppression and Aurora A regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Epigenetic stem cell signature in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

DNA methylation as a therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

RAF/RAS oncogenes and mismatch-repair status

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.12.1917

10.2217/14622416.9.12.1917

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19072648