(Q37346874)

19 August 2017

1 reference

title

Engineered GPCRs as tools to modulate signal transduction (English)

1 reference

G protein-coupled receptor

19 August 2017

0 references

author name string

Ying Pei

1

1 reference

19 August 2017

Sarah C Rogan

2

1 reference

19 August 2017

Feng Yan

3

1 reference

19 August 2017

Bryan L Roth

4

1 reference

19 August 2017

1 December 2008

1 reference

19 August 2017

1 reference

19 August 2017

23

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19 August 2017

313-321

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

19 August 2017

1 reference

Binding of clozapine metabolites and analogues to the histamine H3 receptor in rat brain cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Molecular tinkering of G protein-coupled receptors: an evolutionary success

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

A G(q/11)-coupled mutant histamine H(1) receptor F435A activated solely by synthetic ligands (RASSL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Engineering GPCR signaling pathways with RASSLs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Controlling signaling with a specifically designed Gi-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

G proteins in the heart. A redundant and diverse transmembrane signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Neoceptors: reengineering GPCRs to recognize tailored ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Evidence for kinship between diverse G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

G-protein-coupled receptors at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Mont Sainte-Odile: a sanctuary for GPCRs. Confidence on signal transduction of G-protein-couple receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

The receptors and coding logic for bitter taste

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Molecular simulation of dynorphin A-(1-10) binding to extracellular loop 2 of the kappa-opioid receptor. A model for receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Anatomical profiling of G protein-coupled receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Drugs and valvular heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Engineering receptors activated solely by synthetic ligands (RASSLs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

A genetic approach to access serotonin neurons for in vivo and in vitro studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Modification of the beta 2-adrenergic receptor to engineer a receptor-effector complex for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Controlling signal transduction with synthetic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Engineering the melanocortin-4 receptor to control G(s) signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Development of hydrocephalus in mice expressing the G(i)-coupled GPCR Ro1 RASSL receptor in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Beta-arrestin-biased ligands at seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

A regulatory system for use in gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to kappa-opioid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

The receptors for mammalian sweet and umami taste

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00025.2008

10.1152/PHYSIOL.00025.2008

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference