(Q35153734)

6 August 2017

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title

Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors (English)

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G protein-coupled receptor

6 August 2017

main subject

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author name string

Emmanuel Hermans

series ordinal

1

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6 August 2017

publication date

1 July 2003

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Pharmacology & Therapeutics

6 August 2017

published in

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6 August 2017

volume

99

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6 August 2017

issue

1

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6 August 2017

page(s)

25-44

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Involvement of the carboxyl terminus of the third intracellular loop of the cannabinoid CB1 receptor in constitutive activation of Gs.

6 August 2017

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7 January 2021

AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration

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7 January 2021

Cell cycle-dependent coupling of the vasopressin V1a receptor to different G proteins

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7 January 2021

G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

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7 January 2021

G protein specificity: traffic direction required.

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7 January 2021

Agonist-induced GTPgamma35S binding mediated by human 5-HT(2C) receptors expressed in human embryonic kidney 293 cells

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7 January 2021

Advantages of heterologous expression of human D2long dopamine receptors in human neuroblastoma SH-SY5Y over human embryonic kidney 293 cells

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7 January 2021

Multiple G-protein coupling of the dog thyrotropin receptor

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7 January 2021

Differential regulation of G-protein expression by vasoactive peptides

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7 January 2021

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

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7 January 2021

Mediation of cyclic AMP signaling by the first intracellular loop of the gonadotropin-releasing hormone receptor

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7 January 2021

Constitutively signaling G-protein-coupled receptors and human disease

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7 January 2021

Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function

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7 January 2021

Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling

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7 January 2021

Constitutive activation of the neurotensin receptor 1 by mutation of Phe(358) in Helix seven

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7 January 2021

Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus

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7 January 2021

RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

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7 January 2021

Functional analysis of a human A(1) adenosine receptor/green fluorescent protein/G(i1)alpha fusion protein following stable expression in CHO cells.

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7 January 2021

A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling.

1 reference

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7 January 2021

Receptor-to-effector signaling through G proteins: roles for beta gamma dimers as well as alpha subunits

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7 January 2021

Differential opioid agonist regulation of the mouse mu opioid receptor

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7 January 2021

Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways

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7 January 2021

Phospholipase C isoforms in vascular smooth muscle and their regulation by G-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Molecular tinkering of G protein-coupled receptors: an evolutionary success

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7 January 2021

G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction

1 reference

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7 January 2021

Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G-protein coupled receptor kinases as modulators of G-protein signalling

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7 January 2021

G-protein coupling of mu-opioid receptors (OP3): elevated basal signalling activity

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7 January 2021

Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-

1 reference

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7 January 2021

Dual intracellular signaling pathways mediated by the human cannabinoid CB1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Expression of the mu-opioid receptor in CHO cells: ability of mu-opioid ligands to promote alpha-azidoanilido[32P]GTP labeling of multiple G protein alpha subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Cell Cycle-dependent Coupling of the Calcitonin Receptor to Different G Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Immunoprecipitation of high-affinity, guanine nucleotide-sensitive, solubilized mu-opioid receptors from rat brain: coimmunoprecipitation of the G proteins G(alpha o), G(alpha i1), and G(alpha i3).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Allosteric receptors after 30 years

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https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G protein-coupled receptor allosterism and complexing

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https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications.

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7 January 2021

Metabotropic glutamate 1alpha and adenosine A1 receptors assemble into functionally interacting complexes.

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7 January 2021

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

1 reference

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7 January 2021

The C-terminal third intracellular loop of the rat AT1A angiotensin receptor plays a key role in G protein coupling specificity and transduction of the mitogenic signal

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes in agonist potency and relative intrinsic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Agonist regulation of D(2) dopamine receptor/G protein interaction. Evidence for agonist selection of G protein subtype

1 reference

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7 January 2021

Coupling of endothelin receptors to the ERK/MAP kinase pathway. Roles of palmitoylation and G(alpha)q

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Differential activation of Gq/11 and Gi(3) proteins at 5-hydroxytryptamine(2C) receptors revealed by antibody capture assays: influence of receptor reserve and relationship to agonist-directed trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

1 reference

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7 January 2021

Inverse agonism at heptahelical receptors: concept, experimental approach and therapeutic potential

1 reference

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7 January 2021

Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Interactions of endothelin receptor subtypes A and B with Gi, Go, and Gq in reconstituted phospholipid vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The G protein subunit gene families

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Identification of a Gs coupling domain in the amino terminus of the third intracellular loop of the alpha 2A-adrenergic receptor. Evidence for distinct structural determinants that confer Gs versus Gi coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G-protein-coupled receptors for neurotransmitter amino acids: C-terminal tails, crowded signalosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Inducible expression of alpha 1B-adrenoceptors in DDT1 MF-2 cells: comparison of receptor density and response

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Dual couplings of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Homologous and heterologous regulation of receptor-stimulated phosphoinositide hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Analysis of agonist function at fusion proteins between the IP prostanoid receptor and cognate, unnatural and chimaeric G-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Identification of potential activators of proteinase-activated receptor-2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Functional characterization of three mutations of the endothelin B receptor gene in patients with Hirschsprung's disease: evidence for selective loss of Gi coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Single nucleotide polymorphism of human platelet-activating factor receptor impairs G-protein activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Evidence for the dual coupling of the rat neurotensin receptor with pertussis toxin-sensitive and insensitive G-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Myr+-Gi2 alpha and Go alpha subunits restore the efficacy of opioids, clonidine and neurotensin giving rise to antinociception in G-protein knock-down mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The G-protein betagamma complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The luteinizing hormone/chorionic gonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals

1 reference

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7 January 2021

Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.

1 reference

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7 January 2021

A dominant-negative strategy for studying roles of G proteins in vivo.

1 reference

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7 January 2021

Agonist selective regulation of G proteins by cannabinoid CB(1) and CB(2) receptors

1 reference

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7 January 2021

Rat cerebral cortex corticotropin-releasing hormone receptors: evidence for receptor coupling to multiple G-proteins

1 reference

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7 January 2021

Functional coupling with Galpha(q) and Galpha(i1) protein subunits promotes high-affinity agonist binding to the neurotensin receptor NTS-1 expressed in Escherichia coli

1 reference

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7 January 2021

Functional and clinical consequences of mutations in the FSH receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

In vivo reconstitution of dopamine D2S receptor-mediated G protein activation in baculovirus-infected insect cells: preferred coupling to Gi1 versus Gi2.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Diversity and selectivity of receptor-G protein interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Functional and structural complexity of signal transduction via G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands

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7 January 2021

Heptahelical receptor signaling: beyond the G protein paradigm.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The many faces of G protein signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Structural and functional aspects of G protein-coupled receptor oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Emerging roles for RGS proteins in cell signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Complex involvement of pertussis toxin-sensitive G proteins in the regulation of type 1alpha metabotropic glutamate receptor signaling in baby hamster kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Functional switch from facilitation to inhibition in the control of glutamate release by metabotropic glutamate receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G-protein-independent signaling mediated by metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Role of subunit diversity in signaling by heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Functional coupling of human metabotropic glutamate receptor hmGlu1d: comparison to splice variants hmGlu1a and -1b.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Critical duration of intracellular Ca2+ response required for continuous translocation and activation of cytosolic phospholipase A2.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The proximal portion of the COOH terminus of the oxytocin receptor is required for coupling to g(q), but not g(i). Independent mechanisms for elevating intracellular calcium concentrations from intracellular stores

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

GPCRDB: an information system for G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Truncation of the carboxyl-terminal region of the rat parathyroid hormone (PTH)/PTH-related peptide receptor enhances PTH stimulation of adenylyl cyclase but not phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

W276 mutation in the endothelin receptor subtype B impairs Gq coupling but not Gi or Go coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Stimulated D(1) dopamine receptors couple to multiple Galpha proteins in different brain regions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G-protein-coupled receptor heterodimerization modulates receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Inositol phospholipid metabolism in Xenopus oocytes mediated by endogenous G(o) and Gi proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Agonist-receptor efficacy. I: Mechanisms of efficacy and receptor promiscuity.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Inverse, protean, and ligand-selective agonism: matters of receptor conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Drug efficacy at G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Activation of phospholipases C and D by the novel metabotropic glutamate receptor agonist tADA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Elucidating cell signaling mechanisms using antisense technology

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The intracellular region adjacent to plasma membrane (residues 684-692) of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist-induced adenylate cyclase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The luteinizing hormone receptor activates phospholipase C via preferential coupling to Gi2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Modelling of promiscuous receptor-Gi/Gs-protein coupling and effector response

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to G(s)-, to G(i)-, and to G(q)-coupled effector signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The two-state model of receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Promiscuity, pre-coupling and instability

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A three-state receptor model of agonist action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Strong effects of NT/NN peptides on DA D2 receptors in rat neostriatal sections

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Serine 232 of the alpha(2A)-adrenergic receptor is a protein kinase C-sensitive effector coupling switch

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A large homozygous or heterozygous in-frame deletion within the calcium-sensing receptor's carboxylterminal cytoplasmic tail that causes autosomal dominant hypocalcemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Alternate coupling of receptors to Gs and Gi in pancreatic and submandibular gland cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Bombesin and substance P analogues differentially regulate G-protein coupling to the bombesin receptor. Direct evidence for biased agonism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Site-directed mutations in the third intracellular loop of the serotonin 5-HT(1A) receptor alter G protein coupling from G(i) to G(s) in a ligand-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Genetic, pharmacological and functional analysis of cholecystokinin-1 and cholecystokinin-2 receptor polymorphism in type 2 diabetes and obese patients

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The rat mGlu1d receptor splice variant shares functional properties with the other short isoforms of mGlu1 receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Investigation of the mechanisms of G protein: effector coupling by the human and mouse prostacyclin receptors. Identification of critical species-dependent differences

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The stoichiometry of expression of protein components of the stimulatory adenylyl cyclase cascade and the regulation of information transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Insights into ligand pharmacology using receptor-G-protein fusion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Physiological regulation of G protein-linked signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Regulation of effectors by G-protein alpha- and beta gamma-subunits. Recent insights from studies of the phospholipase c-beta isoenzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Overexpression of G(s)alpha in NG108-15, neuroblastomaXglioma cells: effects on receptor regulation of the stimulatory adenylyl cyclase cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Towards 3D structures of G protein-coupled receptors: a multidisciplinary approach

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Distinct regions of C-terminus of the high affinity neurotensin receptor mediate the functional coupling with pertussis toxin sensitive and insensitive G-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Role of G-protein availability in differential signaling by alpha 2-adrenoceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Selective Coupling of Prostaglandin E Receptor EP3D to Gi and Gs through Interaction of α-Carboxylic Acid of Agonist and Arginine Residue of Seventh Transmembrane Domain

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A single mutation of the neurokinin-2 (NK2) receptor prevents agonist-induced desensitization. Divergent conformational requirements for NK2 receptor signaling and agonist-induced desensitization in Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Membrane organization in G-protein mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G alpha q family members couple parathyroid hormone (PTH)/PTH-related peptide and calcitonin receptors to phospholipase C in COS-7 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Direct evidence for two distinct G proteins coupling with thrombin receptors in human neuroblastoma SH-EP cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by default

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Palmitoylation of human endothelinB. Its critical role in G protein coupling and a differential requirement for the cytoplasmic tail by G protein subtypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Cysteine residues in the carboxyl terminal domain of the endothelin-B receptor are required for coupling with G-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The molecular basis of nephrogenic diabetes insipidus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Mechanisms of endothelin receptor subtype-specific targeting to distinct intracellular trafficking pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The neurokinin A receptor activates calcium and cAMP responses through distinct conformational states

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Angiotensin II enhances the expression of Gialpha in A10 cells (smooth muscle): relationship with adenylyl cyclase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

SKF83959 exhibits biochemical agonism by stimulating [(35)S]GTP gamma S binding and phosphoinositide hydrolysis in rat and monkey brain

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosph

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Galphas- and Galphai/o-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The cholecystokininB receptor is coupled to two effector pathways through pertussis toxin-sensitive and -insensitive G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Amino acid 49 polymorphisms of the human beta1-adrenergic receptor affect agonist-promoted trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Agonist-specific coupling of a cloned Drosophila melanogaster D1-like dopamine receptor to multiple second messenger pathways by synthetic agonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Regulation of phosphoinositide-specific phospholipase C isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G-protein-coupled receptor dimerization: modulation of receptor function.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Switch from facilitation to inhibition of excitatory synaptic transmission by group I mGluR desensitization.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Effect of chronic exposure to naltrexone and opioid selective agonists on G protein mRNA levels in the rat nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A comparison of agonist-specific coupling of cloned human alpha(2)-adrenoceptor subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Dopamine D2 receptor stimulation alters G-protein expression in rat pituitary intermediate lobe melanotropes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G protein G alpha q/11 and G alpha i1,2 are activated by pancreastatin receptors in rat liver: studies with GTP-gamma 35S and azido-GTP-alpha-32P

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A three-state receptor model: predictions of multiple agonist pharmacology for the same receptor type

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Calcium-mediated translocation of cytosolic phospholipase A2 to the nuclear envelope and endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

A C-terminally truncated human parathyroid hormone receptor is functional and activates multiple G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Effects of guanine, inosine, and xanthine nucleotides on beta(2)-adrenergic receptor/G(s) interactions: evidence for multiple receptor conformations

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

GPCR-Galpha fusion proteins: molecular analysis of receptor-G-protein coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Cell type-specific differences in the coupling of recombinant mGlu1alpha receptors to endogenous G protein sub-populations

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

VIP activates G(s) and G(i3) in rat alveolar macrophages and G(s) in HEK293 cells transfected with the human VPAC(1) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

D1Dopamine Receptors Can Interact with Both Stimulatory and Inhibitory Guanine Nucleotide Binding Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Muscarinic receptor stimulation increases regulators of G-protein signaling 2 mRNA levels through a protein kinase C-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Differential signal transduction by five splice variants of the PACAP receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Gonadotropin-releasing hormone receptor couples to multiple G proteins in rat gonadotrophs and in GGH3 cells: evidence from palmitoylation and overexpression of G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Rapid desensitization of the serotonin(2C) receptor system: effector pathway and agonist dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Complexity and diversity of mammalian adenylyl cyclases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Amino-terminal modifications of human parathyroid hormone (PTH) selectively alter phospholipase C signaling via the type 1 PTH receptor: implications for design of signal-specific PTH ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Mammalian membrane-bound adenylyl cyclases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Are we beta-ARKing up the wrong tree? Casein kinase 1 alpha provides an additional pathway for GPCR phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

New thoughts on the role of the beta-gamma subunit in G-protein signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ in coupling efficiency to adenylate cyclase and in agonist-induced receptor desensitization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Thyrotropin activates both the cyclic AMP and the PIP2 cascades in CHO cells expressing the human cDNA of TSH receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

G(i) activator region of alpha(2A)-adrenergic receptors: distinct basic residues mediate G(i) versus G(s) activation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Histamine H2 receptor activates adenylate cyclase and PLC via separate GTP-dependent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The use of stimulus-biased assay systems to detect agonist-specific receptor active states: implications for the trafficking of receptor stimulus by agonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Molecular basis of receptor/G-protein-coupling selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Regulators of G-protein signalling: a novel protein family involved in timely deactivation and desensitization of signalling via heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Contribution of serine residues to constitutive and agonist-induced signaling via the D2S dopamine receptor: evidence for multiple, agonist-specific active conformations

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Comparative analysis of the efficacy of A1 adenosine receptor activation of Gi/o alpha G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-Gi/o alpha fusion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

First intracellular loop of the human cholecystokinin-A receptor is essential for cyclic AMP signaling in transfected HEK-293 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

The PDZ binding motif of the beta 1 adrenergic receptor modulates receptor trafficking and signaling in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

RGS Proteins Determine Signaling Specificity of Gq-coupled Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Efficient functional coupling of the human D3 dopamine receptor to G(o) subtype of G proteins in SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

Conserved extracellular cysteine pair in the M3 muscarinic acetylcholine receptor is essential for proper receptor cell surface localization but not for G protein coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900051-2

7 January 2021

10.1016/S0163-7258(03)00051-2

Identifiers

DOI

1 reference

release_iqhghzhusngpti6yvtthrg6lem

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/iqhghzhusngpti6yvtthrg6lem

24 November 2022

mapped directly with Wikidata item

1 reference