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Gene-gene interactions in the NOD mouse model of type 1 diabetes.
scientific article published on January 2008
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Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
review article
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Europe PubMed Central
title
Gene-gene interactions in the NOD mouse model of type 1 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
main subject
type-1 diabetes
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author
Oliver Burren
series ordinal
6
1 reference
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Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
John A. Todd
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3
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John A Todd
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Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
Linda S Wicker
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7
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Linda S Wicker
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Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
Barry C Healy
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5
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Barry Healy
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Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
author name string
William M Ridgway
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1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Laurence B Peterson
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2
1 reference
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Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
Dan B Rainbow
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4
1 reference
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Europe PubMed Central
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19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
language of work or name
English
1 reference
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publication date
1 January 2008
1 reference
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Europe PubMed Central
PubMed publication ID
19111166
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
published in
Advances in Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
volume
100
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
151-175
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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Diabetes protection and restoration of thymocyte apoptosis in NOD Idd6 congenic strains
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A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice
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Genetic and functional association of the immune signaling molecule 4-1BB (CD137/TNFRSF9) with type 1 diabetes
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7 January 2021
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Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine background
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"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells
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Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice
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7 January 2021
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Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/lty/Bcg genes on chromosome 1
1 reference
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7 January 2021
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A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins.
1 reference
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reference URL
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7 January 2021
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Mapping non-class II H2-linked loci for type 1 diabetes in nonobese diabetic mice
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QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2
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Fuel feeds function: energy metabolism and the T-cell response
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Foxp3-dependent programme of regulatory T-cell differentiation
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Polygenic control of autoimmune diabetes in nonobese diabetic mice
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7 January 2021
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Genetic control of diabetes progression
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7 January 2021
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Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis
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7 January 2021
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The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis
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7 January 2021
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Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice
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7 January 2021
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Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes
1 reference
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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
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7 January 2021
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Colocalization of Mouse Autoimmune Diabetes Loci Idd21.1 and Idd21.2 With IDDM6 (Human) and Iddm3 (Rat)
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7 January 2021
based on heuristic
inferred from DOI database lookup
A type 1 diabetes subgroup with a female bias is characterised by failure in tolerance to thyroid peroxidase at an early age and a strong association with the cytotoxic T-lymphocyte-associated antigen-4 gene
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the transcription factor ARNTL2 as a candidate gene for the type 1 diabetes locus Idd6.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Interactions between Idd5.1/Ctla4 and other type 1 diabetes genes
1 reference
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reference URL
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7 January 2021
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NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis
1 reference
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reference URL
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7 January 2021
based on heuristic
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Genome-wide microarray expression analysis of CD4+ T Cells from nonobese diabetic congenic mice identifies Cd55 (Daf1) and Acadl as candidate genes for type 1 diabetes.
1 reference
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reference URL
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7 January 2021
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Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes susceptibility in nonobese diabetic mice
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Modifier loci condition autoimmunity provoked by Aire deficiency
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In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes.
1 reference
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7 January 2021
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Genetic control of autoimmunity: protection from diabetes, but spontaneous autoimmune biliary disease in a nonobese diabetic congenic strain
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Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localising quantitative trait loci in the NOD mouse model of type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping by Genetic Interaction: High-Resolution Congenic Mapping of the Type 1 Diabetes Loci Idd10 and Idd18 in the NOD Mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A HapMap harvest of insights into the genetics of common disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and physiological association of diabetes susceptibility with raised Na+/H+ exchange activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of the murine type 1 diabetes locus Idd20 by genetic interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fine-mapping of the mouse T lymphocyte fraction (Tlf) locus on chromosome 9: association with autoimmune diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a Structurally Distinct CD101 Molecule Encoded in the 950-kb Idd10 Region of NOD Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse Chromosome 3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DIFFERENTIAL GLYCOSYLATION OF INTERLEUKIN 2, THE MOLECULAR BASIS FOR THE NOD Idd3 TYPE 1 DIABETES GENE?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conditioning the genome identifies additional diabetes resistance loci in Type I diabetes resistant NOR/Lt mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin autoantibodies are associated with islet inflammation but not always related to diabetes progression in NOD congenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three Loci on Mouse Chromosome 6 Influence Onset and Final Incidence of Type I Diabetes in NOD.C3H Congenic Strains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of SLC11A1 (NRAMP1) with persistent oligoarticular and polyarticular rheumatoid factor-negative juvenile idiopathic arthritis in Finnish patients: haplotype analysis in Finnish families
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linkage of rheumatoid arthritis to the candidate gene NRAMP1 on 2q35
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of diabetes in non-obese diabetic I-Ak transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the PTPN22/LYP gene with type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aod2, the locus controlling development of atrophy in neonatal thymectomy-induced autoimmune ovarian dysgenesis, co-localizes with Il2, Fgfb, and Idd3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of autoimmune type 1 diabetes mellitus in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic control of autoimmune diabetes in the NOD mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
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Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type 1 diabetes genes and pathways shared by humans and NOD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective central tolerance induction in NOD mice: genomics and genetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2900806-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0065-2776(08)00806-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PubMed publication ID
19111166
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19111166
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19111166%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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