(Q37360465)

19 August 2017

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title

The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications (English)

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19 August 2017

2

Garth L Nicolson

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19 August 2017

Yasushi Toh

1

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19 August 2017

publication date

31 December 2008

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Clinical & Experimental Metastasis

19 August 2017

published in

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19 August 2017

volume

26

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19 August 2017

issue

3

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19 August 2017

page(s)

215-227

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https://scigraph.springernature.com/pub.10.1007/s10585-008-9233-8

19 August 2017

exact match

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cites work

Mi-2/NuRD: multiple complexes for many purposes

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10585-008-9233-8

The metastasis-associated gene MTA1 is upregulated in advanced ovarian cancer, represses ERbeta, and enhances expression of oncogenic cytokine GRO.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10585-008-9233-8

Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10585-008-9233-8

MTA1, a transcriptional activator of breast cancer amplified sequence 3

21 January 2018

1 reference

12 December 2020

Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation

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12 December 2020

Overexpression of metastatic tumor antigen 1 in hepatocellular carcinoma: Relationship to vascular invasion and estrogen receptor-alpha

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12 December 2020

Direct interaction between metastasis-associated protein 1 and endophilin 3

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12 December 2020

Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1.

1 reference

12 December 2020

Deacetylation of p53 modulates its effect on cell growth and apoptosis

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12 December 2020

Expression of hypoxia-inducible factor-1alpha, histone deacetylase 1, and metastasis-associated protein 1 in pancreatic carcinoma: correlation with poor prognosis with possible regulation

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12 December 2020

Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells

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12 December 2020

Solution structure and antiestrogenic activity of the unique C-terminal, NR-box motif-containing region of MTA1s.

1 reference

12 December 2020

NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans

1 reference

12 December 2020

Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4

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12 December 2020

Identification of tumour antigens by serological analysis of cDNA expression cloning

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12 December 2020

Overexpression of metastasis-associated MTA1 in oral squamous cell carcinomas: correlation with metastasis and invasion

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12 December 2020

Utility of molecular genetic signatures in the delineation of gastric neoplasia

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12 December 2020

Emerging roles of MTA family members in human cancers

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12 December 2020

Upstream determinants of estrogen receptor-alpha regulation of metastatic tumor antigen 3 pathway

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12 December 2020

Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase

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12 December 2020

Connecting estrogen receptor function, transcriptional repression, and E-cadherin expression in breast cancer

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12 December 2020

MTA family of coregulators in nuclear receptor biology and pathology

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12 December 2020

MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer

1 reference

12 December 2020

A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses

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12 December 2020

Expression of the MTA1 mRNA in advanced lung cancer.

1 reference

12 December 2020

Role of C. elegans lin-40 MTA in vulval fate specification and morphogenesis

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12 December 2020

Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells

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12 December 2020

Involvement of heregulin-beta2 in the acquisition of the hormone-independent phenotype of breast cancer cells

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12 December 2020

Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytes.

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12 December 2020

The role of MTA1 gene expression in human hepatocellular carcinoma.

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12 December 2020

Maintenance of Head and Neck Tumor Gene Expression Profiles upon Lymph Node Metastasis

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12 December 2020

Reduced MTA1 expression by RNAi inhibits in vitro invasion and migration of esophageal squamous cell carcinoma cell line

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12 December 2020

The functional characterization of normal and neoplastic human enterochromaffin cells

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12 December 2020

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

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12 December 2020

The role of metastasis-associated protein 1 in prostate cancer progression

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12 December 2020

MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene

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12 December 2020

The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia.

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12 December 2020

MTA family of transcriptional metaregulators in mammary gland morphogenesis and breast cancer

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12 December 2020

Involvement of metastasis tumor antigen 1 in hepatic regeneration and proliferation

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12 December 2020

Metastatic tumor antigen 1 is closely associated with frequent postoperative recurrence and poor survival in patients with hepatocellular carcinoma

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12 December 2020

Analysis of the complete sequence of the novel metastasis-associated candidate gene, mtal, differentially expressed in mammary adenocarcinoma and breast cancer cell lines

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12 December 2020

Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor

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12 December 2020

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

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12 December 2020

Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1alpha

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12 December 2020

Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1.

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12 December 2020

Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator

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12 December 2020

Immunolocalization assessment of metastasis-associated protein 1 in human and mouse mature testes and its association with spermatogenesis

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12 December 2020

MTA1 overexpression correlates significantly with tumor grade and angiogenesis in human breast cancers

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12 December 2020

MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions

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12 December 2020

Interaction of estrogen receptor alpha transactivation domain with MTA1 decreases in old mouse brain.

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12 December 2020

Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein

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12 December 2020

RNA interference of metastasis-associated gene 1 inhibits metastasis of B16F10 melanoma cells in a C57BL/6 mouse model

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12 December 2020

Repression of Six3 by a corepressor regulates rhodopsin expression

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12 December 2020

Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells

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12 December 2020

Breast tumors that overexpress nuclear metastasis-associated 1 (MTA1) protein have high recurrence risks but enhanced responses to systemic therapies

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12 December 2020

A naturally occurring MTA1 variant sequesters oestrogen receptor-alpha in the cytoplasm

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12 December 2020

Identification of Pax5 as a target of MTA1 in B-cell lymphomas

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12 December 2020

Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas

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12 December 2020

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

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12 December 2020

Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells

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12 December 2020

Tumor metastasis-associated human MTA1 gene: its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides

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12 December 2020

MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions

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12 December 2020

Metastasis-associated protein 1 transgenic mice: a new model of spontaneous B-cell lymphomas

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12 December 2020

Metastasis tumor antigens, an emerging family of multifaceted master coregulators.

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12 December 2020

Negative regulation of estrogen receptor alpha transactivation functions by LIM domain only 4 protein

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12 December 2020

Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis

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12 December 2020

Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway

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12 December 2020

Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis

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12 December 2020

Expression of metastasis-associated protein 1 (MTA1) in benign endometrium and endometrial adenocarcinomas.

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12 December 2020

Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma.

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12 December 2020

Expression of the metastasis-associated MTA1 protein and its relationship to deacetylation of the histone H4 in esophageal squamous cell carcinomas

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12 December 2020

Molecular analysis of a candidate metastasis-associated gene, MTA1: possible interaction with histone deacetylase 1.

1 reference

12 December 2020

Correlation of appearance of metastasis-associated protein1 (Mta1) with spermatogenesis in developing mouse testis.

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12 December 2020

Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed.

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12 December 2020

The association of the expression of MTA1, nm23H1 with the invasion, metastasis of ovarian carcinoma

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12 December 2020

Loss of heterozygosity events impeding breast cancer metastasis contain the MTA1 gene

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12 December 2020

Comprehensive analysis of the expression of the metastasis-associated gene 1 in human neoplastic tissue

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12 December 2020

Expression of the MTA1 mRNA in thymoma patients

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12 December 2020

Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1.

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12 December 2020

Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor

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12 December 2020

Metastasis-associated protein 1 inhibits p53-induced apoptosis

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12 December 2020

Expression of MTA1, a metastasis-associated gene with histone deacetylase activity in pancreatic cancer

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12 December 2020

Immunotherapeutic potential of DISC-HSV and OX40L in cancer

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12 December 2020

NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities

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12 December 2020

The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning

1 reference

12 December 2020

10.1007/S10585-008-9233-8

Identifiers

DOI

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19 August 2017

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