(Q37362435)

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The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options

scientific article published on February 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

19 August 2017

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Europe PubMed Central

The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options (English)

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Europe PubMed Central

PubMed publication ID

19 August 2017

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anti-retroviral agent

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Antonella d'Arminio Monforte

4

object named as

Antonella d'Arminio Monforte

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Europe PubMed Central

PubMed publication ID

19 August 2017

author name string

Lidia Gazzola

1

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Camilla Tincati

2

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Giusi Maria Bellistrì

3

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Giulia Marchetti

5

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Europe PubMed Central

PubMed publication ID

19 August 2017

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publication date

1 February 2009

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Europe PubMed Central

PubMed publication ID

19 August 2017

Clinical Infectious Diseases

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Europe PubMed Central

PubMed publication ID

19 August 2017

48

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Europe PubMed Central

PubMed publication ID

19 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

328-337

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

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21 January 2018

Restoration of the immune system with anti-retroviral therapy

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21 January 2018

Long-term outcomes among antiretroviral-naive human immunodeficiency virus-infected patients with small increases in CD4+ cell counts after successful virologic suppression

1 reference

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21 January 2018

Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel.

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21 January 2018

CD4 cell counts at the third month of HAART may predict clinical failure.

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Nitroblue Tetrazolium Test in Hodgkin Disease and Other Malignant Lymphomas

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Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy

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21 January 2018

Patients' characteristics and clinical implications of suboptimal CD4 T-cell gains after 1 year of successful antiretroviral therapy

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21 January 2018

Clinical outcome of HIV-infected antiretroviral-naive patients with discordant immunologic and virologic responses to highly active antiretroviral therapy

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21 January 2018

Risk of non-AIDS-related mortality may exceed risk of AIDS-related mortality among individuals enrolling into care with CD4+ counts greater than 200 cells/mm3.

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21 January 2018

Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study

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21 January 2018

Influence of age on CD4 cell recovery in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy: evidence from the EuroSIDA study

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21 January 2018

Cellular restoration in HIV infected persons treated with abacavir and a protease inhibitor: age inversely predicts naive CD4 cell count increase

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21 January 2018

Response to combination antiretroviral therapy: variation by age.

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21 January 2018

Short-term risk of AIDS according to current CD4 cell count and viral load in antiretroviral drug-naive individuals and those treated in the monotherapy era.

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21 January 2018

Impact of hepatitis C virus on immune restoration in HIV-infected patients who start highly active antiretroviral therapy: a meta-analysis

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21 January 2018

The presence of active hepatitis C virus replication in lymphoid tissue in patients coinfected with human immunodeficiency virus type 1.

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21 January 2018

Hepatitis C virus in lymphoid cells of patients coinfected with human immunodeficiency virus type 1: evidence of active replication in monocytes/macrophages and lymphocytes

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21 January 2018

Clinical progression, survival, and immune recovery during antiretroviral therapy in patients with HIV-1 and hepatitis C virus coinfection: the Swiss HIV Cohort Study

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21 January 2018

Coinfection with hepatitis viruses and outcome of initial antiretroviral regimens in previously naive HIV-infected subjects

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21 January 2018

Immune recovery is associated with persistent rise in hepatitis C virus RNA, infrequent liver test flares, and is not impaired by hepatitis C virus in co-infected subjects

1 reference

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21 January 2018

Effect of hepatitis C infection on progression of HIV disease and early response to initial antiretroviral therapy

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21 January 2018

The Impact of Adherence on CD4 Cell Count Responses Among HIV-Infected Patients

1 reference

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21 January 2018

CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression.

1 reference

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21 January 2018

Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies

1 reference

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21 January 2018

Can immune markers predict subsequent discordance between immunologic and virologic responses to antiretroviral therapy? Adult AIDS Clinical Trials Group

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21 January 2018

Improvement of interleukin 2 production, clonogenic capability and restoration of stromal cell function in human immunodeficiency virus-type-1 patients after highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1086%2F695852

21 January 2018

Immunodysregulation of HIV disease at bone marrow level.

1 reference

https://api.crossref.org/works/10.1086%2F695852

21 January 2018

Altered clonogenic capability and stromal cell function characterize bone marrow of HIV-infected subjects with low CD4+ T cell counts despite viral suppression during HAART.

1 reference

https://api.crossref.org/works/10.1086%2F695852

21 January 2018

Association between larger thymic size and higher thymic output in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1086%2F695852

21 January 2018

T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy

1 reference

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21 January 2018

Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function

1 reference

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21 January 2018

T-cell homeostasis alteration in HIV-1 infected subjects with low CD4 T-cell count despite undetectable virus load during HAART.

1 reference

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21 January 2018

Comparative analysis of T-cell turnover and homeostatic parameters in HIV-infected patients with discordant immune-virological responses to HAART.

1 reference

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21 January 2018

A potential role for interleukin-7 in T-cell homeostasis

1 reference

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21 January 2018

Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

1 reference

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21 January 2018

The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance

1 reference

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21 January 2018

T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

1 reference

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21 January 2018

Low-level viremia and proviral DNA impede immune reconstitution in HIV-1-infected patients receiving highly active antiretroviral therapy.

1 reference

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21 January 2018

Relationship between the size of the human immunodeficiency virus type 1 (HIV-1) reservoir in peripheral blood CD4+ T cells and CD4+:CD8+ T cell ratios in aviremic HIV-1-infected individuals receiving long-term highly active antiretroviral therapy

1 reference

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21 January 2018

HIV disease: fallout from a mucosal catastrophe?

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21 January 2018

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

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21 January 2018

Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection

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Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

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Collagen deposition limits immune reconstitution in the gut

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Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

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Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study

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Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy

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HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy.

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21 January 2018

Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons with </=250/microL CD4 T cells and undetectable plasma virus load

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21 January 2018

Low-dose prolonged intermittent interleukin-2 adjuvant therapy: results of a randomized trial among human immunodeficiency virus-positive patients with advanced immune impairment.

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21 January 2018

Interleukin-2 accelerates CD4 cell reconstitution in HIV-infected patients with severe immunosuppression despite highly active antiretroviral therapy: the ILSTIM study--ANRS 082.

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21 January 2018

Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: a randomized controlled trial

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Interleukin-2-associated viral breakthroughs induce HIV-1-specific CD4 T cell responses in patients on fully suppressive highly active antiretroviral therapy

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Partial immune reconstitution following highly active antiretroviral therapy: can adjuvant interleukin-2 fill the gap?

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Induction and maintenance therapy with intermittent interleukin-2 in HIV-1 infection

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In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients

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IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

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Class-sparing regimens for initial treatment of HIV-1 infection

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Residual low-level viral replication could explain discrepancies between viral load and CD4+ cell response in human immunodeficiency virus-infected patients receiving antiretroviral therapy

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Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic HIV-1 infection

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Clinical and immunological benefits from highly active antiretroviral therapy in spite of limited viral load reduction in HIV type 1 infection.

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Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years

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First-line use of enfuvirtide-containing HAART regimen with dramatic clinical and immunological improvement in three cases

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Unexpected dramatic increase in CD4+ cell count in a patient with AIDS after enfuvirtide treatment despite persistent viremia and resistance mutations

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Cyclosporin A Provides No Sustained Immunologic Benefit to Persons with Chronic HIV‐1 Infection Starting Suppressive Antiretroviral Therapy: Results of a Randomized, Controlled Trial of the AIDS Clinical Trials Group A5138

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Untangling the Immunological Implications of Nadir on CD4+ Cell Recovery during Suppressive Highly Active Antiretroviral Therapy

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Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy

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Editorial Commentary:Immunological Nonresponse to Highly Active Antiretroviral Therapy in HIV‐Infected Subjects: Is the Bone Marrow Impairment Causing CD4 Lymphopenia?

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Changes in thymic function with age and during the treatment of HIV infection

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1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

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