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English
Identification of deleterious mutations within three human genomes
scientific article published on 14 July 2009
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scholarly article
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Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
title
Identification of deleterious mutations within three human genomes
(English)
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Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
author
Sung Chun
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Sung Chun
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Justin C Fay
object named as
Justin C Fay
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publication date
14 July 2009
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stated in
Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
published in
Genome Research
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stated in
Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
volume
19
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Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
page(s)
1553-1561
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Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
issue
9
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Europe PubMed Central
PMCID
2752137
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19 August 2017
cites work
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6 September 2017
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6 September 2017
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6 September 2017
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6 September 2017
Genetic variation in an individual human exome
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6 September 2017
Assessing the evolutionary impact of amino acid mutations in the human genome
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6 September 2017
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6 September 2017
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6 September 2017
Analysis of sequence conservation at nucleotide resolution
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6 September 2017
A second generation human haplotype map of over 3.1 million SNPs
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6 September 2017
The diploid genome sequence of an individual human
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6 September 2017
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6 September 2017
Deleterious SNP prediction: be mindful of your training data!
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6 September 2017
Predicting the effects of amino acid substitutions on protein function
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Efficiency of truncation selection
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6 September 2017
AN ESTIMATE OF THE MUTATIONAL DAMAGE IN MAN FROM DATA ON CONSANGUINEOUS MARRIAGES
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6 September 2017
Initial sequence of the chimpanzee genome and comparison with the human genome
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6 September 2017
Trade-offs in detecting evolutionarily constrained sequence by comparative genomics
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6 September 2017
The scale of mutational variation in the murid genome
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6 September 2017
Distribution and intensity of constraint in mammalian genomic sequence
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6 September 2017
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6 September 2017
HyPhy: hypothesis testing using phylogenies
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6 September 2017
Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol
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6 September 2017
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6 September 2017
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6 September 2017
Our load of mutations
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6 September 2017
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6 September 2017
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6 September 2017
Human non-synonymous SNPs: server and survey
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Ratios of radical to conservative amino acid replacement are affected by mutational and compositional factors and may not be indicative of positive Darwinian selection
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Testing the neutral theory of molecular evolution with genomic data from Drosophila.
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1 reference
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PubMed Central
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6 September 2017
Are rare variants responsible for susceptibility to complex diseases?
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PubMed Central
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6 September 2017
Predicting deleterious amino acid substitutions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752137
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6 September 2017
SNPs, protein structure, and disease.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752137
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6 September 2017
Prediction of deleterious human alleles
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752137
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6 September 2017
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6 September 2017
A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome
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PubMed Central
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6 September 2017
Amino acid difference formula to help explain protein evolution
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PubMed Central
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6 September 2017
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PubMed Central
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6 September 2017
Accounting for human polymorphisms predicted to affect protein function
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14 September 2017
Mutations affecting fitness in Drosophila populations
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14 September 2017
Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation
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PubMed Central
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28 September 2017
The mutational meltdown in asexual populations
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28 September 2017
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
1 reference
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PubMed Central
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26 June 2018
Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752137
retrieved
2 September 2018
Identifiers
DOI
10.1101/GR.092619.109
1 reference
stated in
Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
PMCID
2752137
1 reference
stated in
Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
PubMed ID
19602639
1 reference
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Europe PubMed Central
PMCID
2752137
retrieved
19 August 2017
ResearchGate publication ID
26671245
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