(Q37365394)

English

Loss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy.

scientific article published on 28 October 2013

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scholarly article

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Europe PubMed Central

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28 February 2020

Loss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy (English)

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28 February 2020

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congestive heart failure

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based on heuristic

inferred from title

14

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28 February 2020

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Zhongbing Lu

1

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28 February 2020

Xin Xu

2

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28 February 2020

John Fassett

3

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28 February 2020

Dongmin Kwak

4

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28 February 2020

Xiaoyu Liu

5

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28 February 2020

Xinli Hu

6

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28 February 2020

Huan Wang

7

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28 February 2020

Haipeng Guo

8

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28 February 2020

Dachun Xu

9

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28 February 2020

Shuo Yan

10

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28 February 2020

Edward O McFalls

11

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28 February 2020

Fei Lu

12

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28 February 2020

Robert J Bache

13

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28 February 2020

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28 October 2013

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28 February 2020

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28 February 2020

63

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28 February 2020

1

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28 February 2020

128-135

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28 February 2020

Potential of gene therapy as a treatment for heart failure

1 reference

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Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: heart failure causes severe lung disease

1 reference

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6 September 2017

Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Oxidative stress regulates left ventricular PDE5 expression in the failing heart

1 reference

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6 September 2017

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

1 reference

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6 September 2017

Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Cardiac autophagy is a maladaptive response to hemodynamic stress

1 reference

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6 September 2017

A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

1 reference

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6 September 2017

Global translational responses to oxidative stress impact upon multiple levels of protein synthesis.

1 reference

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6 September 2017

Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses

1 reference

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6 September 2017

Coping with stress: eIF2 kinases and translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy

1 reference

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6 September 2017

Activation of GCN2 in UV-irradiated cells inhibits translation

1 reference

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6 September 2017

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079623

6 September 2017

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

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6 September 2017

Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression

1 reference

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6 September 2017

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death

1 reference

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28 September 2017

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.

1 reference

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26 June 2018

Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis.

1 reference

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2 September 2018

Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice.

1 reference

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2 September 2018

Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury.

1 reference

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2 September 2018

Effects of oral amino acid supplements on cardiac function and remodeling in patients with type 2 diabetes with mild-to-moderate left ventricular dysfunction

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24166753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral amino acid supplements improve exercise capacities in elderly patients with chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24166753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24166753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SERCA overexpression reduces hydroxyl radical injury in murine myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/24166753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic postischemic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24166753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/HYPERTENSIONAHA.113.02313

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Europe PubMed Central

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28 February 2020

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Europe PubMed Central

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28 February 2020

PubMed publication ID

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28 February 2020

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