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Activation of GCN2 in UV-irradiated cells inhibits translation
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
title
Activation of GCN2 in UV-irradiated cells inhibits translation
(English)
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
main subject
Eukaryotic translation initiation factor 2, subunit 1 alpha
1 reference
stated in
GOA release 2020-03-11
Eukaryotic translation initiation factor 2 alpha kinase 4
1 reference
stated in
GOA release 2020-03-11
author
Anne-Claude Gingras
series ordinal
4
0 references
Nahum Sonenberg
series ordinal
9
object named as
Nahum Sonenberg
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
David Ron
object named as
David Ron
series ordinal
8
0 references
Juan Jose Berlanga
object named as
Juan Jose Berlanga
series ordinal
5
1 reference
stated in
ORCID Public Data File 2021
author name string
Jing Deng
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
Heather P. Harding
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
Brian Raught
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
Donalyn Scheuner
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
Randal J. Kaufman
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
language of work or name
English
0 references
publication date
6 August 2002
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
published in
Current Biology
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
volume
12
1 reference
stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
issue
15
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stated in
PubMed
PubMed ID
12176355
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31 January 2017
page(s)
1279–1286
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stated in
PubMed
PubMed ID
12176355
retrieved
31 January 2017
cites work
Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA damage response: putting checkpoints in perspective
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
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inferred from DOI database lookup
Evolution of the two-step model for UV-mutagenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular responses to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinase cascades as regulators of stress responses
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by the JNK group of MAP kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
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inferred from DOI database lookup
The p38 signal transduction pathway: activation and function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
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inferred from DOI database lookup
Mutagenesis and growth delay induced in Escherichia coli by near-ultraviolet radiations
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
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inferred from DOI database lookup
Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis.
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of translational initiation during cellular responses to stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated translation initiation controls stress-induced gene expression in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
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inferred from DOI database lookup
The mammalian ultraviolet response is triggered by activation of src tyrosine kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
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inferred from DOI database lookup
The UV response involving the Ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
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inferred from DOI database lookup
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sensor-less checkpoint activation?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PERK mediates cell-cycle exit during the mammalian unfolded protein response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perk is essential for translational regulation and cell survival during the unfolded protein response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of vertical slab isoelectric focusing and immunoblotting to evaluate steady-state phosphorylation of eIF2 alpha in cultured cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901037-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(02)01037-0
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2271143
OpenCitations bibliographic resource ID
2271143
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2271143
PubMed ID
12176355
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2271143
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