(Q37366061)

English

Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells

scientific article

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells (English)

1 reference

Europe PubMed Central

20 August 2017

1 reference

based on heuristic

inferred from title

Howard L. Weiner

3

object named as

Howard L Weiner

1 reference

Europe PubMed Central

20 August 2017

Francisco J. Quintana

2

object named as

Francisco J Quintana

1 reference

Europe PubMed Central

20 August 2017

author name string

Henry Yim Wu

1

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

1 November 2008

1 reference

Europe PubMed Central

20 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

20 August 2017

181

1 reference

Europe PubMed Central

20 August 2017

6038-6050

1 reference

Europe PubMed Central

20 August 2017

9

1 reference

Europe PubMed Central

20 August 2017

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Th17: the third member of the effector T cell trilogy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Immune therapies of autoimmune diseases: are we approaching a real cure?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Infectious tolerance and the long-term acceptance of transplanted tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Failure of CD25+ T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Autoantibodies, lupus and the science of sabotage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Monoclonal antibody therapy in experimental allergic encephalomyelitis and multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

A critical role for IL-21 in regulating immunoglobulin production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

CXCR5(+) T cells: follicular homing takes center stage in T-helper-cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

A chemokine-driven positive feedback loop organizes lymphoid follicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Co-stimulation and selection for T-cell help for germinal centres: the role of CD28 and OX40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Regulation of naive T cell differentiation by varying the potency of TCR signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

6 September 2017

Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

28 September 2017

Treatment of murine lupus with anti-CD4 monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

28 September 2017

Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: correlation with severity of renal histology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

28 September 2017

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

26 June 2018

Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

26 June 2018

Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

26 June 2018

Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Breakdown of mucosal immunity in the gut and resultant systemic sensitization by oral antigens in a murine model for systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Use of a novel elution regimen reveals the dominance of polyreactive antinuclear autoantibodies in lupus kidneys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753458

2 September 2018

Combined anti-CD2 and anti-CD3 receptor monoclonal antibodies induce donor-specific tolerance in a cardiac transplant model

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of immune tolerance by administration of monoclonal antibody to L3T4

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of injection of anti-CD4 and anti-CD8 monoclonal antibodies on the development of experimental systemic lupus erythematosus in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of naturally occuring diabetes in primates by unmodified islet xenografts without chronic immunosuppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Very low-dose tolerance with nucleosomal peptides controls lupus and induces potent regulatory T cell subsets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mucosal milieu creates tolerogenic dendritic cells and T(R)1 and T(H)3 regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone peptide-induced nasal tolerance: suppression of murine lupus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of regulatory T cells in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of nasal tolerance in lupus prone mice is T-cell anergy induced by immature B cells that lack B7 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Immature human dendritic cells express latency-associated peptide and inhibit T cell activation in a TGF-beta-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of oral tolerance in (NZB X NZW)F1 mice is antigen specific and appears to parallel antibody patterns in human systemic lupus erythematosus (SLE)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18941193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.181.9.6038

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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