(Q37368872)

English

Antitumor agents 252. Application of validated QSAR models to database mining: discovery of novel tylophorine derivatives as potential anticancer agents

scientific article published on January 2007

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Antitumor agents 252. Application of validated QSAR models to database mining: discovery of novel tylophorine derivatives as potential anticancer agents (English)

1 reference

Europe PubMed Central

20 August 2017

0 references

Alexander Tropsha

7

object named as

Alexander Tropsha

1 reference

Europe PubMed Central

20 August 2017

6

object named as

Kuo-Hsiung Lee

1 reference

Europe PubMed Central

20 August 2017

author name string

Shuxing Zhang

1

1 reference

Europe PubMed Central

20 August 2017

Linyi Wei

2

1 reference

Europe PubMed Central

20 August 2017

Ken Bastow

3

1 reference

Europe PubMed Central

20 August 2017

Weifan Zheng

4

1 reference

Europe PubMed Central

20 August 2017

Arnold Brossi

5

1 reference

Europe PubMed Central

20 August 2017

publication date

1 January 2007

1 reference

Europe PubMed Central

20 August 2017

Journal of Computer - Aided Molecular Design

1 reference

Europe PubMed Central

20 August 2017

21

1 reference

Europe PubMed Central

20 August 2017

1-3

1 reference

Europe PubMed Central

20 August 2017

97-112

1 reference

Europe PubMed Central

20 August 2017

https://scigraph.springernature.com/pub.10.1007/s10822-007-9102-6

0 references

A novel automated lazy learning QSAR (ALL-QSAR) approach: method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

Development of quantitative structure-binding affinity relationship models based on novel geometrical chemical descriptors of the protein-ligand interfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

Rational selection of training and test sets for the development of validated QSAR models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

Natural products as sources of new drugs over the period 1981-2002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

Cryptopleurine Resistance: Genetic Locus for a 40 S Ribosomal Component in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

6 September 2017

Antitumor agents 251: synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

14 September 2017

Novel mode of action of tylophorine analogs as antitumor compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

14 September 2017

Induction of apoptosis in a human erythroleukemic cell line K562 by tylophora alkaloids involves release of cytochrome c and activation of caspase 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

28 September 2017

Improved QSARs for predictive toxicology of halogenated hydrocarbons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

28 September 2017

Comparison of algorithms for dissimilarity-based compound selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

An evaluation of structural descriptors and clustering methods for use in diversity selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

Antineoplastic agents, 103. The isolation and structure of hypoestestatins 1 and 2 from the East African Hypoëstes verticillaris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

Inhibition of protein synthesis in Ehrlich ascites-tumour cells by the phenanthrene alkaloids tylophorine, tylocrebrine and cryptopleurine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

Mode of action of tylocrebrine: effects on protein and nucleic acid synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebrine, and tubulosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

26 June 2018

Chemometric analysis of ligand receptor complementarity: identifying Complementary Ligands Based on Receptor Information (CoLiBRI).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

2 September 2018

Application of validated QSAR models of D1 dopaminergic antagonists for database mining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

2 September 2018

Application of predictive QSAR models to database mining: identification and experimental validation of novel anticonvulsant compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

2 September 2018

Predictive QSAR modeling based on diversity sampling of experimental datasets for the training and test set selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

2 September 2018

Quantitative structure-activity relationships of mutagenic and carcinogenic aromatic amines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

2 September 2018

Novel variable selection quantitative structure--property relationship approach based on the k-nearest-neighbor principle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754562

2 September 2018

THE ANTILEUKEMIA ACTIVITY OF TYLOCREBRINE

1 reference

https://pubmed.ncbi.nlm.nih.gov/17340042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkaloids of Tylophora III: New Alkaloids of Tylophora indica (Burm) Merrill and Tylophora dalzellii Hook. f

1 reference

https://pubmed.ncbi.nlm.nih.gov/17340042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of dihydrofolate reductase and cell growth activity by the phenanthroindolizidine alkaloids pergularinine and tylophorinidine: the in vitro cytotoxicity of these plant alkaloids and their potential as antimicrobial and anticancer agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17340042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thymidylate synthase and cell growth by the phenanthroindolizidine alkaloids pergularinine and tylophorinidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17340042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenanthroindolizidine Alkaloids and Their Cytotoxicity from the Leaves of Ficus septica

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.3987/COM-02-9615

Identifiers

10.1007/S10822-007-9102-6

1 reference

Europe PubMed Central

20 August 2017

DBLP publication ID

journals/jcamd/ZhangWBZBLT07

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

ResearchGate publication ID

0 references

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