(Q37371294)

English

Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation

scientific article published on August 1997

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scholarly article

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5 November 2019

Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation (English)

1 reference

Europe PubMed Central

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5 November 2019

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Timothy A. Graubert

1

1 reference

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5 November 2019

author name string

J F DiPersio

2

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5 November 2019

J H Russell

3

1 reference

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5 November 2019

T J Ley

4

1 reference

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5 November 2019

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publication date

1 August 1997

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5 November 2019

Journal of Clinical Investigation

1 reference

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5 November 2019

100

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5 November 2019

904-911

1 reference

Europe PubMed Central

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5 November 2019

4

1 reference

Europe PubMed Central

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5 November 2019

The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Immune function in mice lacking the perforin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Globin gene expression in erythroid human fetal liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Purified perforin induces target cell lysis but not DNA fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Transcriptional activation of the human cytotoxic serine protease gene CSP-B in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Quantitative polymerase chain reaction analysis of cytotoxic cell proteinase gene transcripts in T cells. Pattern of expression is dependent on the nature of the stimulus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Expression and downregulation of cytotoxic cell protease 1 or Granzyme 'B' transcripts during myeloid differentiation of interleukin-3-dependent murine stem cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

6 September 2017

Contenders in FasL/TNF death signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

14 September 2017

Die and let live: eliminating dangerous lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

28 September 2017

Cytokine dysregulation as a mechanism of graft versus host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

28 September 2017

Granzyme B and perforin lytic proteins are expressed in CD34+ peripheral blood progenitor cells mobilized by chemotherapy and granulocyte colony-stimulating factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

28 September 2017

Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

28 September 2017

Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

26 June 2018

Bone marrow transplantation for chronic myelogenous leukemia in chronic phase. Increased risk for relapse associated with T-cell depletion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

26 June 2018

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

26 June 2018

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508263

2 September 2018

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of granzyme B in murine models of acute graft-versus-host disease and graft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A hammerhead ribozyme that cleaves perforin and fas-ligand RNAs in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms responsible for granzyme B-independent cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CTLA-1 and CTLA-3 serine esterase transcripts are detected mostly in cytotoxic T cells, but not only and not always

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo primed mouse T cells selectively express T cell-specific serine proteinase-1 and the proteinase-like molecules granzyme B and C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for CD95 ligand in preventing graft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/9259590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119606

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9259590%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9259590%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9259590%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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