(Q37372036)

English

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

scientific article published on September 1997

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Europe PubMed Central

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5 November 2019

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q (English)

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5 November 2019

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quantitative trait locus

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author name string

A V Lembertas

1

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5 November 2019

Y C Chagnon

3

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5 November 2019

J S Fisler

4

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5 November 2019

C H Warden

5

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5 November 2019

D A Purcell-Huynh

6

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5 November 2019

F T Dionne

7

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5 November 2019

J Gagnon

8

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5 November 2019

A Nadeau

9

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5 November 2019

C Bouchard

11

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5 November 2019

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1 September 1997

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5 November 2019

Journal of Clinical Investigation

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5 November 2019

100

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5 November 2019

5

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5 November 2019

1240-1247

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5 November 2019

The gross composition of the body

1 reference

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6 September 2017

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1 reference

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6 September 2017

Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Absence of linkage of obesity and energy metabolism to markers flanking homologues of rodent obesity genes in Pima Indians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Extreme obesity may be linked to markers flanking the human OB gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Indication for linkage of the human OB gene region with extreme obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Identification and expression cloning of a leptin receptor, OB-R

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Segregation analysis of fat mass and other body composition measures derived from underwater weighing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: application to nonobese diabetic (NOD) mouse and human insulin-dependent diabetes mellitus (IDDM)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Localization of the genes encoding the melanocortin-2 (adrenocorticotropic hormone) and melanocortin-3 receptors to chromosomes 18p11.2 and 20q13.2-q13.3 by fluorescence in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Genetic dissection of complex traits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Structure and function of ASP, the human homolog of the mouse agouti gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Identification of four chromosomal loci determining obesity in a multifactorial mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Regulation of lipoprotein lipase immunoreactive mass in isolated human adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Maps of linkage and synteny homologies between mouse and man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

High-resolution linkage mapping for susceptibility genes in human polygenic disease: insulin-dependent diabetes mellitus and chromosome 11q.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Genetic analysis of a complex, multifactorial disease, autoimmune type 1 (insulin-dependent) diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

6 September 2017

Dietary obesity in nine inbred mouse strains

1 reference

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6 September 2017

Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

28 September 2017

Human/mouse homology relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

28 September 2017

The human obesity gene map: the 1996 update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

28 September 2017

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

1 reference

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26 June 2018

Polygenic control of autoimmune diabetes in nonobese diabetic mice

1 reference

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Use of Polyethylene Glycol to Separate Free and Antibody-Bound Peptide Hormones in Radioimmunoassays†

1 reference

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26 June 2018

Common major gene inheritance of extreme overweight.

1 reference

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26 June 2018

Linkage Analysis of Maturity-Onset Diabetes of the Young With Microsatellite Polymorphisms: No Linkage to ADA or GLUT2 Genes in Two Families

1 reference

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26 June 2018

Molecular characterization of the mouse agouti locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

26 June 2018

Algorithms for a location database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

26 June 2018

An exploratory investigation of genetic linkage with body composition and fatness phenotypes: the Québec Family Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

2 September 2018

Suggestive linkages between markers on human 1p32-p22 and body fat and insulin levels in the Quebec Family Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

2 September 2018

The Body-Mass Index of Twins Who Have Been Reared Apart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508301

3 December 2018

Inhibition of adenosine 3',5'-monophosphate accumulation and lipolysis by adenosine analogs in human subcutaneous adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The response to long-term overfeeding in identical twins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of dietary obesity in AKR/J x SWR/J mice: segregation of the trait and identification of a linked locus on chromosome 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genes for endothelin 3, vitamin D 24-hydroxylase, and melanocortin 3 receptor map to distal mouse Chromosome 2, in the region of conserved synteny with human Chromosome 20

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of the melanocortin peptides required for activation of melanocortin-3 and melanocortin-4 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influences of genes and shared family environment on adult body mass index assessed in an adoption study by a comprehensive path model

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histocompatibility genes of mce. 8. The alleles of the H-1 locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic pleiotropy for resting metabolic rate with fat-free mass and fat mass: the Québec Family Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of linkage between human obesity and the mouse agouti homologous region (20q11.2) or other markers spanning chromosome 20q

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: An approach for the genetic dissection of complex traits

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenic strains reveal effects of the epilepsy quantitative trait locus, El2, separate from other El loci

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histocompatibility genes of the mouse. I. Demonstration of weak histocompatibility differences by immunization and controlled tumor dosage

1 reference

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12 December 2020

based on heuristic

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The investigation of linkage between a quantitative trait and a marker locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9276742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119637

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9276742%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9276742%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9276742%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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