(Q37372247)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Nuclear Phosphoproteomic Screen Uncovers ACLY as Mediator of IL-2-induced Proliferation of CD4+ T lymphocytes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Kerman Aloria

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Jesus M Arizmendi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

Ana María Zubiaga Elordieta

1 April 2020

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Blagoy Blagoev

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Irina Kratchmarova

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Jone Mitxelena

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Virginia Sánchez-Quiles

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Vyacheslav Akimov

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

publication date

11 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

Molecular & Cellular Proteomics

1 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

2076-2092

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5083085/fullTextXML

inferred from PubMed Central ID database lookup

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6 September 2017

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6 September 2017

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Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration

6 September 2017

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Acetyl-CoA induces transcription of the key G1 cyclin CLN3 to promote entry into the cell division cycle in Saccharomyces cerevisiae

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'

6 September 2017

1 reference

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Adoptive immunotherapy for cancer: harnessing the T cell response

6 September 2017

1 reference

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Combining immunotherapy and targeted therapies in cancer treatment

6 September 2017

1 reference

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Rac1 protein regulates glycogen phosphorylase activation and controls interleukin (IL)-2-dependent T cell proliferation.

6 September 2017

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IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

6 September 2017

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Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics

6 September 2017

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

6 September 2017

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Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.

6 September 2017

1 reference

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When signaling kinases meet histones and histone modifiers in the nucleus

6 September 2017

1 reference

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Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes

6 September 2017

1 reference

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Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

6 September 2017

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Andromeda: a peptide search engine integrated into the MaxQuant environment

6 September 2017

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Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

6 September 2017

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

6 September 2017

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ATP-citrate lyase links cellular metabolism to histone acetylation

6 September 2017

1 reference

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T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.

6 September 2017

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6 September 2017

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Dissection of the insulin signaling pathway via quantitative phosphoproteomics

6 September 2017

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6 September 2017

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NetworKIN: a resource for exploring cellular phosphorylation networks

6 September 2017

1 reference

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Genome wide transcriptional analysis of resting and IL2 activated human natural killer cells: gene expression signatures indicative of novel molecular signaling pathways

6 September 2017

1 reference

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Chromatin modifications and their function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

6 September 2017

1 reference

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6 September 2017

1 reference

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Criteria for effective design, construction, and gene knockdown by shRNA vectors

6 September 2017

1 reference

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An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

ATP citrate lyase inhibition can suppress tumor cell growth

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

ATP citrate lyase is an important component of cell growth and transformation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Bcl-2 overexpression enhances tumor-specific T-cell survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

6 September 2017

1 reference

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The main function of IL-2 is to promote the development of T regulatory cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Interleukin 2 signaling involves the phosphorylation of Stat proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Only high-affinity receptors for interleukin 2 mediate internalization of ligand

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

The nuclear protein ALY binds to and modulates the activity of transcription factor E2F2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Signaling T-cell survival and death by IL-2 and IL-15.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Histone H4 acetylation during interleukin-2 stimulation of mouse T cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Off-line high-pH reversed-phase fractionation for in-depth phosphoproteomics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

PPARγ ligand production is tightly linked to clonal expansion during initiation of adipocyte differentiation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Chimeric γc cytokine receptors confer cytokine independent engraftment of human T lymphocytes.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Evidence for the existence of an HP1-mediated subcode within the histone code.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5083085

Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylat

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27067055

12 December 2020

inferred from PubMed ID database lookup

A protocol for designing siRNAs with high functionality and specificity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27067055

12 December 2020

inferred from PubMed ID database lookup

Sequence of sites on ATP-citrate lyase and phosphatase inhibitor 2 phosphorylated by multifunctional protein kinase (a glycogen synthase kinase 3 like kinase)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27067055

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/MCP.M115.057158

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27067055%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

27067055

1 reference