(Q81246968)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

A protocol for designing siRNAs with high functionality and specificity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Amanda Birmingham

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Emily Anderson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Kevin Sullivan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Angela Reynolds

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Queta Boese

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Devin Leake

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Jon Karpilow

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Anastasia Khvorova

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

2068-2078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17853862%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nprot.2007.278

7 January 2020

exact match

0 references

cites work

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RNA interference is mediated by 21- and 22-nucleotide RNAs

31 March 2020

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RNA interference and small interfering RNAs

31 March 2020

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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

31 March 2020

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Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

31 March 2020

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Rational siRNA design for RNA interference

31 March 2020

1 reference

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RNAi-mediated targeting of heterochromatin by the RITS complex

31 March 2020

1 reference

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RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.278

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

31 March 2020

1 reference

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A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

31 March 2020

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HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

31 March 2020

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Effects on RNAi of the tight structure, sequence and position of the targeted region.

31 March 2020

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Functional siRNAs and miRNAs Exhibit Strand Bias

31 March 2020

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Asymmetry in the assembly of the RNAi enzyme complex

31 March 2020

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An algorithm for selection of functional siRNA sequences.

31 March 2020

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Design of a genome-wide siRNA library using an artificial neural network

31 March 2020

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Sequence characteristics of functional siRNAs

31 March 2020

1 reference

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Demonstration of two novel methods for predicting functional siRNA efficiency

31 March 2020

1 reference

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Efficient prediction of siRNAs with siRNArules 1.0: an open-source JAVA approach to siRNA algorithms

31 March 2020

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An accurate and interpretable model for siRNA efficacy prediction

31 March 2020

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Synthetic lethal screen identification of chemosensitizer loci in cancer cells

31 March 2020

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Induction of the interferon response by siRNA is cell type- and duplex length-dependent

31 March 2020

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

31 March 2020

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A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

31 March 2020

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Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

31 March 2020

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Expression profiling reveals off-target gene regulation by RNAi

31 March 2020

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

31 March 2020

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

31 March 2020

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Minimizing the risk of reporting false positives in large-scale RNAi screens

31 March 2020

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

31 March 2020

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Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies

31 March 2020

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Inhibition of gammaherpesvirus replication by RNA interference

31 March 2020

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The contributions of dsRNA structure to Dicer specificity and efficiency

31 March 2020

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More complete gene silencing by fewer siRNAs: transparent optimized design and biophysical signature

31 March 2020

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siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference

31 March 2020

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Integrated siRNA design based on surveying of features associated with high RNAi effectiveness

31 March 2020

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Sfold web server for statistical folding and rational design of nucleic acids

31 March 2020

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31 March 2020

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siRNA function in RNAi: a chemical modification analysis

31 March 2020

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Chemical modification of gene silencing oligonucleotides for drug discovery and development

31 March 2020

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Positional effect of chemical modifications on short interference RNA activity in mammalian cells

31 March 2020

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Chemical modification of siRNAs to improve serum stability without loss of efficacy.

31 March 2020

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

31 March 2020

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