(Q37374904)

20 August 2017

1 reference

title

Rescuing the subprime meltdown in insulin exocytosis in diabetes (English)

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20 August 2017

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Edwin P Kwan

1

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20 August 2017

Herbert Y Gaisano

series ordinal

2

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20 August 2017

language of work or name

English

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publication date

1 January 2009

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Annals of the New York Academy of Sciences

20 August 2017

published in

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20 August 2017

volume

1152

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20 August 2017

page(s)

154-164

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Insulin granule dynamics in pancreatic beta cells

20 August 2017

cites work

1 reference

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Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients

21 January 2018

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Beta-cell hypertrophy in fa/fa rats is associated with basal glucose hypersensitivity and reduced SNARE protein expression

21 January 2018

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Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment

21 January 2018

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Munc18-1 in secretion: lonely Munc joins SNARE team and takes control.

21 January 2018

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Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming.

21 January 2018

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Open syntaxin docks synaptic vesicles

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc 18-1 and granuphilin collaborate during insulin granule exocytosis

21 January 2018

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21 January 2018

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SNAREs--engines for membrane fusion

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

New insights into the molecular mechanisms of priming of insulin exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Molecular determinants of regulated exocytosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Synaptotagmin V and IX isoforms control Ca2+ -dependent insulin exocytosis.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Priming in exocytosis: attaining fusion-competence after vesicle docking

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Molecular mechanisms of active zone function

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Regulation of insulin exocytosis by Munc13-1.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Beta-cell protein kinases and the dynamics of the insulin response to glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

UNC-13 interaction with syntaxin is required for synaptic transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Identification of the minimal protein domain required for priming activity of Munc13-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta -cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

The specificity of SNARE pairing in biological membranes is mediated by both proof-reading and spatial segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

HOPS proofreads the trans-SNARE complex for yeast vacuole fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc18-1 binds directly to the neuronal SNARE complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Functionally and spatially distinct modes of munc18-syntaxin 1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Antagonistic regulation of synaptic vesicle priming by Tomosyn and UNC-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Ca2+-dependent activator protein for secretion 1 is critical for constitutive and regulated exocytosis but not for loading of transmitters into dense core vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

PKC-1 regulates secretion of neuropeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

UNC-31 (CAPS) is required for dense-core vesicle but not synaptic vesicle exocytosis in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

PKA activation bypasses the requirement for UNC-31 in the docking of dense core vesicles from C. elegans neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

The biology of incretin hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Cell physiology of cAMP sensor Epac

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Phosphorylation of synaptic vesicle proteins: modulation of the alpha SNAP interaction with the core complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Phosphorylation of syntaphilin by cAMP-dependent protein kinase modulates its interaction with syntaxin-1 and annuls its inhibitory effect on vesicle exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Visualization of sequential exocytosis in rat pancreatic islet beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Differential regulation of granule-to-granule and granule-to-plasma membrane fusion during secretion from rat pituitary lactotrophs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Sequential exocytosis of insulin granules is associated with redistribution of SNAP25

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Foxa2 controls vesicle docking and insulin secretion in mature Beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Two cAMP-dependent pathways differentially regulate exocytosis of large dense-core and small vesicles in mouse beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Molecular anatomy of a trafficking organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

The plasma membrane Q-SNARE syntaxin 2 enters the zymogen granule membrane during exocytosis in the pancreatic acinar cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

In vitro assays to measure SNARE-mediated vesicle fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Hypothesis: single and chain release of insulin secretory granules is related to anionic transport at exocytotic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Multiple forms of "kiss-and-run" exocytosis revealed by evanescent wave microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

The R-SNARE Motif of Tomosyn Forms SNARE Core Complexes with Syntaxin 1 and SNAP-25 and Down-regulates Exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

Sequential-replenishment mechanism of exocytosis in pancreatic acini

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2008.03990.X

10.1111/J.1749-6632.2008.03990.X

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference