(Q37377422)

English

Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels

scientific article published on 14 September 2009

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels (English)

1 reference

Europe PubMed Central

20 August 2017

author name string

Kensuke Takada

1

1 reference

Europe PubMed Central

20 August 2017

Stephen C Jameson

2

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

14 September 2009

1 reference

Europe PubMed Central

20 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

20 August 2017

206

1 reference

Europe PubMed Central

20 August 2017

2253-2269

1 reference

Europe PubMed Central

20 August 2017

10

1 reference

Europe PubMed Central

20 August 2017

Variability and robustness in T cell activation from regulated heterogeneity in protein levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

The clone size of peripheral CD8 T cells is regulated by TCR promiscuity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Naive and memory CD4+ T cell survival controlled by clonal abundance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

T cell homeostasis: keeping useful T cells alive and live T cells useful

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Regulation of mature T cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Control of T cell viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Elimination In Vivo of Developing T Cells by Natural Killer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Are major histocompatibility complex molecules involved in the survival of naive CD4+ T cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

In vivo survival and homeostatic proliferation of natural killer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Self-recognition and the regulation of CD4+ T cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Rare, structurally homologous self-peptides promote thymocyte positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Maintaining the norm: T-cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

MHC-dependent survival of naïve T cells? A complicated answer to a simple question

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Sensory adaptation in naive peripheral CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Autoreactivity, dynamic tuning and selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

How alpha beta T cells deal with induced TCR alpha ablation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

The life span of naive alpha/beta T cells in secondary lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

T cell receptor antagonist peptides induce positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Peripheral selection of the T cell repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

6 September 2017

Noncognate interaction with MHC class II molecules is essential for maintenance of T cell metabolism to establish optimal memory CD4 T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

14 September 2017

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

14 September 2017

CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

14 September 2017

Death of peripheral CD8+ T cells in the absence of MHC class I is Fas-dependent and not blocked by Bcl-xL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

14 September 2017

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

28 September 2017

Reactivity and specificity of CD8+ T cells in mice with defects in the MHC class I antigen-presenting pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

28 September 2017

Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

28 September 2017

Fine tuning of TCR signaling by CD5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

26 June 2018

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

26 June 2018

Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

26 June 2018

Turnover of naive- and memory-phenotype T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

26 June 2018

Specificity and flexibility in thymic selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

26 June 2018

Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

26 June 2018

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

A role for TCR affinity in regulating naive T cell homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

Impairment of immunological memory in the absence of MHC despite survival of memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

How much TCR does a T cell need?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

Supra-agonist peptides enhance the reactivation of memory CTL responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

Persistence of memory CD8 T cells in MHC class I-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

MHC class I is required for peripheral accumulation of CD8+ thymic emigrants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757867

2 September 2018

Characterizing the Impact of CD8 Antibodies on Class I MHC Multimer Binding

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20082553

21 January 2018

A role for CD5 in TCR-mediated signal transduction and thymocyte selection

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20082553

21 January 2018

Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20082553

21 January 2018

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC class I-positive dendritic cells (DC) control CD8 T cell homeostasis in vivo: T cell lymphopenia as a prerequisite for DC-mediated homeostatic proliferation of naive CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of CD8 and TCR binding to Class I MHC ligands following T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-recognition is crucial for maintaining the peripheral CD4+ T-cell pool in a nonlymphopenic environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse MHC class I tetramers that are unable to bind to CD8 reveal the need for CD8 engagement in order to activate naive CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor Sensitivity: When T cells Lose Their Sense of Self

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20082553

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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0 references

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