(Q37378179)

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Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

scientific article published on 18 April 2016

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Europe PubMed Central

20 August 2017

Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity (English)

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Europe PubMed Central

20 August 2017

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Human Induced Pluripotent Stem Cells

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based on heuristic

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based on heuristic

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Helen M Blau

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3 June 2020

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Paul W Burridge

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Elena Matsa

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Haodi Wu

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Sang-Ging Ong

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Alexandra Holmström

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Alex C Chang

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Michael J Coronado

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Antje D Ebert

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Joshua W Knowles

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Melinda L Telli

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Ronald M Witteles

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3 June 2020

Daniel Bernstein

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Joseph C Wu

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3 June 2020

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18 April 2016

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Nature Medicine

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22

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547-556

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3 June 2020

5

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3 June 2020

describes a project that uses

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https://scigraph.springernature.com/pub.10.1038/nm.4087

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A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

1 reference

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6 September 2017

SIRT1 suppresses doxorubicin-induced cardiotoxicity by regulating the oxidative stress and p38MAPK pathways

1 reference

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6 September 2017

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1 reference

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6 September 2017

Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes

1 reference

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6 September 2017

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes

1 reference

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6 September 2017

Cardiovascular disease in adult survivors of childhood cancer

1 reference

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6 September 2017

The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells

1 reference

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6 September 2017

Adverse effects of doxorubicin and its metabolic product on cardiac RyR2 and SERCA2A.

1 reference

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6 September 2017

Chemically defined generation of human cardiomyocytes

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6 September 2017

P53 inhibition exacerbates late-stage anthracycline cardiotoxicity

1 reference

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6 September 2017

Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells

1 reference

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6 September 2017

Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

1 reference

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6 September 2017

Genomic instability in pluripotent stem cells: implications for clinical applications

1 reference

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6 September 2017

Origins and implications of pluripotent stem cell variability and heterogeneity

1 reference

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6 September 2017

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

1 reference

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6 September 2017

NCBI GEO: archive for functional genomics data sets--update

1 reference

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6 September 2017

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

1 reference

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6 September 2017

Architecture of the human regulatory network derived from ENCODE data

1 reference

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6 September 2017

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3

1 reference

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6 September 2017

From pluripotency to distinct cardiomyocyte subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Decline in the use of anthracyclines for breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Disruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Chemotherapy induced cardiomyopathy: pathogenesis, monitoring and management

1 reference

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6 September 2017

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

1 reference

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6 September 2017

Regulation of interferon-inducible proteins by doxorubicin via interferon γ-Janus tyrosine kinase-signal transducer and activator of transcription signaling in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Mechanisms and management of doxorubicin cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Chemically defined conditions for human iPSC derivation and culture

1 reference

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6 September 2017

Integrative genomics viewer

1 reference

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6 September 2017

Doxorubicin pathways: pharmacodynamics and adverse effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Independent component analysis: mining microarray data for fundamental human gene expression modules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

1 reference

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6 September 2017

TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements.

1 reference

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6 September 2017

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

1 reference

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6 September 2017

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1 reference

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6 September 2017

Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy

1 reference

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6 September 2017

Improved scoring of functional groups from gene expression data by decorrelating GO graph structure

1 reference

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6 September 2017

Molecular pharmacology of the interaction of anthracyclines with iron

1 reference

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6 September 2017

Application of independent component analysis to microarrays

1 reference

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6 September 2017

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

1 reference

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6 September 2017

Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials

1 reference

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6 September 2017

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

1 reference

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6 September 2017

Frequency and risk factors of subclinical cardiotoxicity after anthracycline therapy in children: a systematic review.

1 reference

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6 September 2017

Independent component analysis: algorithms and applications

1 reference

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6 September 2017

Embryonic stem cell lines derived from human blastocysts

1 reference

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6 September 2017

Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin

1 reference

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6 September 2017

A clinicopathologic analysis of adriamycin cardiotoxicity

1 reference

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6 September 2017

Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro

1 reference

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6 September 2017

Risk factors for doxorubicin-induced congestive heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

6 September 2017

A non-invasive platform for functional characterization of stem-cell-derived cardiomyocytes with applications in cardiotoxicity testing

1 reference

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14 September 2017

Nongenetic method for purifying stem cell-derived cardiomyocytes

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14 September 2017

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.

1 reference

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14 September 2017

Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells

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28 September 2017

Patient-Specific Pluripotent Stem Cells in Doxorubicin Cardiotoxicity: A New Window Into Personalized Medicine

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26 June 2018

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

1 reference

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26 June 2018

Selective inhibition of muscle gene expression by oxidative stress in cardiac cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

26 June 2018

Effects of histidine and N-acetylcysteine on doxorubicin-induced cardiomyopathy in rats.

1 reference

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2 September 2018

Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086256

2 September 2018

Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage

1 reference

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2 September 2018

Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin

1 reference

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2 September 2018

Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma

1 reference

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2 September 2018

Effect of anthracycline antibiotics on oxygen radical formation in rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative study on the relation between structural and functional properties of the hearts from three different mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical involvement in doxorubicin-induced electrophysiological alterations in rat papillary muscle fibres

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of interaction between anthraquinone drugs and the calcium-release channel from cardiac sarcoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of human-induced pluripotent stem cell-derived cardiomyocytes: bioenergetics and utilization in safety screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics and metabolism of doxorubicin and epirubicin in patients with metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of the adriamycin-cardiolipin complex structure using attenuated total reflection infrared spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction and prevention of chemotherapy-induced cardiomyopathy: can it be done?

1 reference

https://pubmed.ncbi.nlm.nih.gov/27089514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment-related cardiotoxicity in survivors of childhood cancer

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug-induced oxidative stress and toxicity

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1/2 mutation carriers are potentially at higher cardiovascular risk

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Induced pluripotent stem cells in cardiovascular drug discovery

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Systems biology approaches to adverse drug effects: the example of cardio-oncology

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of anthracycline-induced cardiotoxicity: challenges and opportunities

1 reference

https://api.crossref.org/works/10.1038%2FNM.4087

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/NM.4087

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27089514%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

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3 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27089514%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

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