(Q37379223)

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Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway.

scientific article published on 07 July 2009

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Europe PubMed Central

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2 February 2020

Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway (English)

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2 February 2020

J. Silvio Gutkind

9

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2 February 2020

Lalage M Wakefield

10

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2 February 2020

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Yansong Bian

1

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2 February 2020

Anita Terse

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2 February 2020

Juan Du

3

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2 February 2020

Bradford Hall

4

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2 February 2020

Alfredo Molinolo

5

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2 February 2020

Pin Zhang

6

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2 February 2020

Wanjun Chen

7

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2 February 2020

Kathleen C Flanders

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2 February 2020

Ashok B Kulkarni

11

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2 February 2020

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7 July 2009

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2 February 2020

Cancer Research

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2 February 2020

69

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2 February 2020

14

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2 February 2020

5918-5926

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2 February 2020

Immunoexpression of cyclooxygenase-2 and p53 in oral squamous cell carcinoma.

1 reference

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6 September 2017

Dysregulated molecular networks in head and neck carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

TGFbeta in Cancer

1 reference

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6 September 2017

Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment

1 reference

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6 September 2017

Cancer statistics, 2008

1 reference

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6 September 2017

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

1 reference

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6 September 2017

Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity

1 reference

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6 September 2017

Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

The logic of TGFbeta signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Specificity and versatility in tgf-beta signaling through Smads

1 reference

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6 September 2017

Somatic acquisition and signaling of TGFBR1*6A in cancer

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6 September 2017

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

1 reference

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6 September 2017

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Molecular pathology of head-and-neck cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Focus on head and neck cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

PTEN: one gene, many syndromes

1 reference

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6 September 2017

The two faces of transforming growth factor beta in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Role of tissue stroma in cancer cell invasion

1 reference

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6 September 2017

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

1 reference

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6 September 2017

Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis

1 reference

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6 September 2017

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

1 reference

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6 September 2017

Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis

1 reference

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6 September 2017

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

1 reference

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6 September 2017

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758611

6 September 2017

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

1 reference

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14 September 2017

Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth

1 reference

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TGF-beta receptor I conditional knockout mice develop spontaneous squamous cell carcinoma.

1 reference

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14 September 2017

Disruption of transforming growth factor beta-Smad signaling pathway in head and neck squamous cell carcinoma as evidenced by mutations of SMAD2 and SMAD4.

1 reference

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14 September 2017

Attenuated type II TGF-beta receptor signalling in human malignant oral keratinocytes induces a less differentiated and more aggressive phenotype that is associated with metastatic dissemination

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Oral mucosal carcinogenesis in SENCAR mice.

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2 September 2018

Frequent alterations of Smad signaling in human head and neck squamous cell carcinomas: a tissue microarray analysis.

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Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases

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Analysis of TGF-beta type I receptor for mutations and polymorphisms in head and neck cancers.

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A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

1 reference

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12 December 2020

based on heuristic

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Endoglin (CD105) is expressed on immature blood vessels and is a marker for survival in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19584284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking transforming growth factor beta signaling in transgenic epidermis accelerates chemical carcinogenesis: a mechanism associated with increased angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19584284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19584284

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-4623

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Europe PubMed Central

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2 February 2020

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Europe PubMed Central

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2 February 2020

PubMed publication ID

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Europe PubMed Central

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2 February 2020

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