(Q37383704)

20 August 2017

APC mutations in colorectal tumors with mismatch repair deficiency (English)

1 reference

20 August 2017

1 reference

13

1 reference

20 August 2017

12

B Vogelstein

1 reference

20 August 2017

11

K W Kinzler

1 reference

20 August 2017

J Huang

1

1 reference

20 August 2017

N Papadopoulos

2

1 reference

20 August 2017

A J McKinley

3

1 reference

20 August 2017

S M Farrington

4

1 reference

20 August 2017

L J Curtis

5

1 reference

20 August 2017

A H Wyllie

6

1 reference

20 August 2017

S Zheng

7

1 reference

20 August 2017

J K Willson

8

1 reference

20 August 2017

S D Markowitz

9

1 reference

20 August 2017

P Morin

10

1 reference

20 August 2017

language of work or name

English

0 references

publication date

1 August 1996

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

1 reference

20 August 2017

93

1 reference

20 August 2017

17

1 reference

20 August 2017

9049-9054

1 reference

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Microsatellite instability in cancer of the proximal colon

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

The APC gene product in normal and tumor cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutation of a mutL homolog in hereditary colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutations of the APC (adenomatous polyposis coli) gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutator phenotypes in human colorectal carcinoma cell lines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Inactivation of both APC alleles in human and mouse tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutations of GTBP in genetically unstable cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Genetic instability occurs in the majority of young patients with colorectal cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

The 1993-94 Généthon human genetic linkage map

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

APC mutation analysis by chemical cleavage of mismatch and a protein truncation assay in familial adenomatous polyposis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Genetic alterations during colorectal-tumor development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

APC mutations occur early during colorectal tumorigenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

6 September 2017

Familial polyposis coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Spontaneous mutations at aprt locus in a mammalian cell line defective in mismatch recognition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Clues to the pathogenesis of familial colorectal cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Hypermutability and mismatch repair deficiency in RER+ tumor cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Cell culture of human colon adenomas and carcinomas.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Molecular diagnosis of familial adenomatous polyposis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Molecular determinants of dysplasia in colorectal lesions.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38593

Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons

2 September 2018

1 reference

12 December 2020

Hereditary non-polyposis colorectal cancer — morphologies, genes and mutations

1 reference

12 December 2020

Loss of Apc+ in intestinal adenomas from Min mice

1 reference

12 December 2020

Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias

1 reference

12 December 2020

Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients

1 reference

12 December 2020

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1 reference

12 December 2020

Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas

1 reference

12 December 2020

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

1 reference

12 December 2020

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

1 reference

12 December 2020

Fast and sensitive silver staining of DNA in polyacrylamide gels

1 reference

12 December 2020

Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP)

1 reference

12 December 2020

Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history

1 reference

12 December 2020

Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome

1 reference

12 December 2020

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.93.17.9049

1 reference

20 August 2017

0 references

1 reference

20 August 2017

1 reference