(Q37385793)

20 August 2017

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title

Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? (English)

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20 August 2017

Hildegard M Schuller

1

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20 August 2017

language of work or name

English

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publication date

5 February 2009

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20 August 2017

published in

Nature Reviews Cancer

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20 August 2017

volume

9

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20 August 2017

issue

3

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20 August 2017

page(s)

195-205

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20 August 2017

cites work

Tobacco-related diseases

1 reference

The new World Health Organization classification of lung tumours

31 March 2020

1 reference

Effect of cigarette smoking on major histological types of lung cancer: a meta-analysis

31 March 2020

1 reference

Tobacco smoke carcinogens and lung cancer

31 March 2020

1 reference

Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment

31 March 2020

1 reference

Neurobiology of nicotine addiction: implications for smoking cessation treatment

31 March 2020

1 reference

Human neuronal nicotinic receptors

31 March 2020

1 reference

Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines

31 March 2020

1 reference

Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines

31 March 2020

1 reference

Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells

31 March 2020

1 reference

Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent-extracted forms from Torpedo marmorata electric organ

31 March 2020

1 reference

Isolation of acetylcholine receptors

31 March 2020

1 reference

The acetylcholine receptor: Progress report

31 March 2020

1 reference

Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain

31 March 2020

1 reference

Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research

31 March 2020

1 reference

Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells

31 March 2020

1 reference

Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

31 March 2020

1 reference

31 March 2020

Ion channels and cancer

1 reference

Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival

31 March 2020

1 reference

Nicotinic acetylcholine receptors containing alpha 7 subunits on rat cortical neurons do not undergo long-lasting inactivation even when up-regulated by chronic nicotine exposure

31 March 2020

1 reference

Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal.

31 March 2020

1 reference

Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs

31 March 2020

1 reference

Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma

31 March 2020

1 reference

GABA B receptor is a novel drug target for pancreatic cancer

31 March 2020

1 reference

Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells

31 March 2020

1 reference

Block by phytoestrogens of recombinant human neuronal nicotinic receptors

31 March 2020

1 reference

International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising.

31 March 2020

1 reference

The immunosuppressive effects of nicotine during human mixed lymphocyte reaction

31 March 2020

1 reference

Expression and function of genes encoding cholinergic components in murine immune cells

31 March 2020

1 reference

Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts

31 March 2020

1 reference

Decreased bombesin peptide response to cigarette smoking in schizophrenia

31 March 2020

1 reference

Nicotine and sympathetic neurotransmission

31 March 2020

1 reference

Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons.

31 March 2020

1 reference

Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells

31 March 2020

1 reference

Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages.

31 March 2020

1 reference

Interaction between adrenaline and epidermal growth factor in the control of liver glycogenolysis in mouse

31 March 2020

1 reference

Beta-adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas

31 March 2020

1 reference

The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers

31 March 2020

1 reference

Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells

31 March 2020

1 reference

Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma

31 March 2020

1 reference

Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines

31 March 2020

1 reference

Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells

31 March 2020

1 reference

Interaction of tobacco-specific toxicants with nicotinic cholinergic regulation of fetal pulmonary neuroendocrine cells: implications for pediatric lung disease

31 March 2020

1 reference

Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells

31 March 2020

1 reference

Serotonin release and cell proliferation are under the control of alpha-bungarotoxin-sensitive nicotinic receptors in small-cell lung carcinoma cell lines

31 March 2020

1 reference

Expression of nicotinic receptors in normal and tumoral pulmonary neuroendocrine cells (PNEC).

31 March 2020

1 reference

Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion

31 March 2020

1 reference

Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation

31 March 2020

1 reference

Inhibition of protein-kinase-C--dependent cell proliferation of human lung cancer cell lines by the dihydropyridine dexniguldipine

31 March 2020

1 reference

Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors

31 March 2020

1 reference

Protein kinase A balances the growth factor-induced Ras/ERK signaling

31 March 2020

1 reference

Nicotine, lung and cancer

31 March 2020

1 reference

Angiogenesis and the role of the endothelial nicotinic acetylcholine receptor

31 March 2020

1 reference

Nitrosamines as nicotinic receptor ligands

31 March 2020

1 reference

Neurotransmission and cancer: implications for prevention and therapy

31 March 2020

1 reference

Impaired lung function and lung cancer incidence in a cohort of Swedish construction workers

31 March 2020

1 reference

The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation?

31 March 2020

1 reference

Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters

31 March 2020

1 reference

Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: implications for chemoprevention in smokers

31 March 2020

1 reference

Nicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis

31 March 2020

1 reference

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

31 March 2020

1 reference

Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells

31 March 2020

1 reference

NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells.

31 March 2020

1 reference

Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells

31 March 2020

1 reference

Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin

31 March 2020

1 reference

Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways

31 March 2020

1 reference

The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells

31 March 2020

1 reference

Recurrent exposure to nicotine differentiates human bronchial epithelial cells via epidermal growth factor receptor activation

31 March 2020

1 reference

Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy

31 March 2020

1 reference

Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers

31 March 2020

1 reference

Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2.

31 March 2020

1 reference

Nicotine promotes colon tumor growth and angiogenesis through beta-adrenergic activation

31 March 2020

1 reference

The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors

31 March 2020

1 reference

SLURP-1 and -2 in normal, immortalized and malignant oral keratinocytes

31 March 2020

1 reference

Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes

31 March 2020

1 reference

Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes

31 March 2020

1 reference

SLURP-2: A novel cholinergic signaling peptide in human mucocutaneous epithelium.

31 March 2020

1 reference

Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke

31 March 2020

1 reference

Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation via beta-adrenoceptor-dependent transactivation of extracellular signal-regulated kinase/cyclooxygenase-2 pathway.

31 March 2020

1 reference

Epidermal growth factor-induced esophageal cancer cell proliferation requires transactivation of beta-adrenoceptors

31 March 2020

1 reference

Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway

31 March 2020

1 reference

Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells.

31 March 2020

1 reference

The brain within the tumor: new roles for axon guidance molecules in cancers.

31 March 2020

1 reference

Neoneurogenesis and the neuro-neoplastic synapse

31 March 2020

1 reference

The cancer's nervous tooth: Considering the neuronal crosstalk within tumors

31 March 2020

1 reference

Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.

31 March 2020

1 reference

Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine.

31 March 2020

1 reference

The neurobiology of dopamine signaling

31 March 2020

1 reference

Stress hormone-mediated invasion of ovarian cancer cells

31 March 2020

1 reference

Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells

31 March 2020

1 reference

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

31 March 2020

1 reference

Carcinogenic food contaminants

31 March 2020

1 reference

Nitrosamine and related food intake and gastric and oesophageal cancer risk: a systematic review of the epidemiological evidence

31 March 2020

1 reference

Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

31 March 2020

1 reference

Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia

31 March 2020

1 reference

Growth stimulation of human pulmonary adenocarcinoma cells and small airway epithelial cells by beta-carotene via activation of cAMP, PKA, CREB and ERK1/2.

31 March 2020

1 reference

Nonclassical action of retinoic acid on the activation of the cAMP response element-binding protein in normal human bronchial epithelial cells

31 March 2020

1 reference

Cyclic adenosine monophosphate-dependent cell type-specific modulation of mitogenic signaling by retinoids in normal and neoplastic lung cells

31 March 2020

1 reference

Microclimate Influence on Mineral and Metabolic Profiles of Grape Berries

31 March 2020

1 reference

Wine and resveratrol: mechanisms of cancer prevention?

31 March 2020

1 reference

Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells

31 March 2020

1 reference

12 December 2020

The neurotransmitter gamma-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells.

1 reference

12 December 2020

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation

1 reference

12 December 2020

Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines

1 reference

12 December 2020

Evaluation of the potential anti-cancer activity of the antidepressant sertraline in human colon cancer cell lines and in colorectal cancer-xenografted mice

1 reference

12 December 2020

Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans

1 reference

12 December 2020

Nicotinic receptor-mediated activation by the tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells

1 reference

12 December 2020

The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid

1 reference

12 December 2020

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese

1 reference

12 December 2020

Theophylline stimulates cAMP-mediated signaling associated with growth regulation in human cells from pulmonary adenocarcinoma and small airway epithelia.

1 reference

12 December 2020

A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors

1 reference

12 December 2020

Chronic obstructive pulmonary disease: definition and epidemiology

1 reference

12 December 2020

Simultaneous exposure to nicotine and hyperoxia causes tumors in hamsters.

1 reference

12 December 2020

Carbon dioxide potentiates the mitogenic effects of nicotine and its carcinogenic derivative, NNK, in normal and neoplastic neuroendocrine lung cells via stimulation of autocrine and protein kinase C-dependent mitogenic pathways.

1 reference

12 December 2020

Evaluation of PDE4 inhibition for COPD.

1 reference

12 December 2020

Structure and function of neuronal nicotinic acetylcholine receptors

1 reference

12 December 2020

Caffeine stimulates the proliferation of human lung adenocarcinoma cells and small airway epithelial cells via activation of PKA, CREB and ERK1/2.

1 reference

12 December 2020

PDE4 inhibitors as potential therapeutic agents in the treatment of COPD-focus on roflumilast

1 reference

12 December 2020

Alcohol consumption and risk of prostate cancer in middle-aged men

1 reference

12 December 2020

Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers

1 reference

12 December 2020

Activation of voltage-operated Ca2+-channels in human small cell lung carcinoma by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

1 reference

12 December 2020

Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma

1 reference

12 December 2020

Pathobiology of lung tumors induced in hamsters by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and the modulating effect of hyperoxia

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2590

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Dimensions Publication ID

20 August 2017

1023606172

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