(Q37394682)

English

Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin "Trojan Horse" antibiotics and synthetic desferridanoxamine-antibiotic conjugates

scientific article published on 17 February 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1 reference

Europe PubMed Central

Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin "Trojan Horse" antibiotics and synthetic desferridanoxamine-antibiotic conjugates (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

0 references

2

object named as

Ute Möllmann

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Timothy A Wencewicz

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Timothy E Long

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Marvin J Miller

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

17 February 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

22

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

633-648

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

https://scigraph.springernature.com/pub.10.1007/s10534-009-9218-3

0 references

Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents

1 reference

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Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure-activity relationships of the nucleobase domain of 5'-O-[N-(salicyl)sulfamoyl]adenosine

1 reference

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6 September 2017

Coevolution: mankind and microbes

1 reference

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6 September 2017

Structural biology of bacterial iron uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Strategic paradigm shifts in the antimicrobial drug discovery process of the 21st century

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Siderophore-based iron acquisition and pathogen control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Albomycin is an effective antibiotic, as exemplified with Yersinia enterocolitica and Streptococcus pneumoniae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Albomycin uptake via a ferric hydroxamate transport system of Streptococcus pneumoniae R6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis

1 reference

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6 September 2017

Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity

1 reference

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6 September 2017

Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species

1 reference

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6 September 2017

Siderophore-antibiotic conjugates used as trojan horses against Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin

1 reference

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6 September 2017

Screening system for xenosiderophores as potential drug delivery agents in mycobacteria

1 reference

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6 September 2017

Iron metabolism in pathogenic bacteria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Total synthesis of the siderophore danoxamine

1 reference

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6 September 2017

Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Studies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Siderophores: Structure and Function of Microbial Iron Transport Compounds

1 reference

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6 September 2017

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

1 reference

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6 September 2017

Modes of action and inhibitory activities of new siderophore-beta-lactam conjugates that use specific iron uptake pathways for entry into bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

6 September 2017

Microbial iron transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

14 September 2017

Penetration of beta-lactam antibiotics into their target enzymes in Pseudomonas aeruginosa: comparison of a highly sensitive mutant with its parent strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

14 September 2017

Intracellular activation of albomycin in Escherichia coli and Salmonella typhimurium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

14 September 2017

Identification and characterization of porins in Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

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Indirect method for assessing the penetration of beta-lactamase-nonsusceptible penicillins and cephalosporins in Escherichia coli strains

1 reference

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28 September 2017

Uptake and Conversion of the Antibiotic Albomycin by Escherichia coli K-12

1 reference

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Synthesis and activities of pyoverdin-quinolone adducts: a prospective approach to a specific Therapy against Pseudomonas aeruginosa

1 reference

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26 June 2018

Some experiments with semisynthetic sideromycins

1 reference

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26 June 2018

Siderophores as drug delivery agents: application of the "Trojan Horse" strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2766516

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Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: linkage of ribosomal and nonribosomal peptides to form "trojan horse" antibiotics

1 reference

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Antimicrobial surfaces through natural product hybrids

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2 September 2018

The bacteria fight back

1 reference

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2 September 2018

Recent studies on albomycin, a new antibiotic.

1 reference

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Synthesis and Biological Activity of Trisand Tetrakiscatecholate Siderophores Based on Poly-aza Alkanoic Acids or Alkylbenzoic Acids and their Conjugates with β-Lactam Antibiotics

1 reference

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2 September 2018

Total synthesis of desferrisalmycin B.

1 reference

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2 September 2018

Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds

1 reference

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New synthetic siderophores and their beta-lactam conjugates based on diamino acids and dipeptides

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Active transport of siderophore-mimicking antibacterials across the outer membrane.

1 reference

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Clonal dissemination of two MRSA strains in Germany

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Constitution of ferrimycin A1

1 reference

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Ferrimycin A, a new iron-containing antibiotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/19221879

12 December 2020

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vanA-mediated high-level glycopeptide resistance in Enterococcus faecium from animal husbandry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19221879

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Synthesis of pyochelin-norfloxacin conjugates

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19221879

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Identifiers

10.1007/S10534-009-9218-3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

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