(Q37395035)

20 August 2017

1 reference

title

Drug substances presented as sulfonic acid salts: overview of utility, safety and regulation (English)

1 reference

20 August 2017

David P Elder

1

1 reference

20 August 2017

David J Snodin

series ordinal

2

1 reference

20 August 2017

publication date

1 March 2009

1 reference

Journal of Pharmacy and Pharmacology

20 August 2017

published in

1 reference

20 August 2017

volume

61

1 reference

20 August 2017

issue

3

1 reference

20 August 2017

page(s)

269-278

1 reference

On the role of alkylating mechanisms, O-alkylation and DNA-repair in genotoxicity and mutagenicity of alkylating methanesulfonates of widely varying structures in bacterial systems

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Structure-activity considerations and in vitro approaches to assess the genotoxicity of 19 methane-, benzene- and toluenesulfonic acid esters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Toxicological overview of impurities in pharmaceutical products

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Dehydration, hydration behavior, and structural analysis of fenoprofen calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Salt formation to improve drug solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Investigation of solubility and dissolution of a free base and two different salt forms as a function of pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Residues of genotoxic alkyl mesylates in mesylate salt drug substances: real or imaginary problems?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

A tiered approach to threshold of regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Genotoxicity of monofunctional methanesulphonates in the SOS chromotest as a function of alkylation mechanisms. A comparison with the mutagenicity in S. typhimurium TA100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

Safety evaluation of food flavorings

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

International Commission for Protection Against Environmental Mutagens and Carcinogens. The subtlety of alkylating agents in reactions with biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.03.0001

21 January 2018

Identifiers

DOI

10.1211/JPP.61.03.0001

1 reference

20 August 2017

1 reference