(Q37398645)

20 August 2017

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title

Actin dynamics and functions in the interphase nucleus: moving toward an understanding of nuclear polymeric actin (English)

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20 August 2017

Randall S Gieni

1

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20 August 2017

Michael J Hendzel

series ordinal

2

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20 August 2017

publication date

1 February 2009

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Biochemistry and Cell Biology

20 August 2017

published in

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20 August 2017

volume

87

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20 August 2017

issue

1

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20 August 2017

page(s)

283-306

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NuMA influences higher order chromatin organization in human mammary epithelium

20 August 2017

cites work

1 reference

The state of the filament

21 January 2018

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Identification and functional characterization of protein 4.1R and actin-binding sites in erythrocyte beta spectrin: regulation of the interactions by phosphatidylinositol-4,5-bisphosphate

21 January 2018

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F-actin-dependent insolubility of chromatin-modifying components

21 January 2018

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WASP-interacting protein (WIP): working in polymerisation and much more

21 January 2018

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Evolution of the gelsolin family of actin-binding proteins as novel transcriptional coactivators.

21 January 2018

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Nuclear architecture in the light of gene expression and cell differentiation studies

21 January 2018

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Electron spectroscopic imaging of chromatin

21 January 2018

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Large-scale chromatin structure and function.

21 January 2018

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Multiple and surprising new functions for emerin, a nuclear membrane protein

21 January 2018

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21 January 2018

Actin up in the nucleus

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Do higher-order chromatin structure and nuclear reorganization play a role in regulating Hox gene expression during development?

21 January 2018

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Modelling molecular mechanisms of breast cancer and invasion: lessons from the normal gland

21 January 2018

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Actin and ARPs: action in the nucleus.

21 January 2018

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A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes

21 January 2018

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Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes

21 January 2018

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Molecular characterization of the hdm2-p53 interaction

21 January 2018

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Transcriptional regulation at the nuclear pore complex

21 January 2018

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The Nck family of adapter proteins: regulators of actin cytoskeleton

21 January 2018

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Nuclear PI(4,5)P(2): a new place for an old signal

21 January 2018

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Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling

21 January 2018

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21 January 2018

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Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells

21 January 2018

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Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription

21 January 2018

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Nuclear actin and actin-related proteins in chromatin dynamics

21 January 2018

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Cofilin, actin and their complex observed in vivo using fluorescence resonance energy transfer

21 January 2018

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Long-range directional movement of an interphase chromosome site

21 January 2018

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Crystallographic Conformers of Actin in a Biologically Active Bundle of Filaments

21 January 2018

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Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes

21 January 2018

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Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells

21 January 2018

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Higher order chromatin architecture in the cell nucleus: on the way from structure to function.

21 January 2018

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Coupling of the nucleus and cytoplasm: role of the LINC complex

21 January 2018

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Activation of Arp2/3 complex: addition of the first subunit of the new filament by a WASP protein triggers rapid ATP hydrolysis on Arp2

21 January 2018

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Increased importin-beta-dependent nuclear import of the actin modulating protein CapG promotes cell invasion

21 January 2018

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Mechanochemistry of protein 4.1's spectrin-actin-binding domain: ternary complex interactions, membrane binding, network integration, structural strengthening

21 January 2018

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Mechanisms underlying intranuclear rod formation.

21 January 2018

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Actin binding proteins: regulation of cytoskeletal microfilaments

21 January 2018

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Actin-dependent intranuclear repositioning of an active gene locus in vivo.

21 January 2018

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New insights into actin filament dynamics

21 January 2018

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Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD

21 January 2018

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Rho GTPases in cell biology

21 January 2018

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An actin-myosin complex on actively transcribing genes.

21 January 2018

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The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture

21 January 2018

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The p400 complex is an essential E1A transformation target

21 January 2018

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Intranuclear actin bundles induced by dimethyl sulfoxide in interphase nucleus of Dictyostelium

21 January 2018

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A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

21 January 2018

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Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

21 January 2018

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Distinct effects of Rac1 on differentiation of primary avian myoblasts

21 January 2018

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Nuclear actin is partially associated with Cajal bodies in human cells in culture and relocates to the nuclear periphery after infection of cells by adenovirus 5.

21 January 2018

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Mechanotransduction from the ECM to the genome: are the pieces now in place?

21 January 2018

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The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells

21 January 2018

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Dynamic nuclear actin assembly by Arp2/3 complex and a baculovirus WASP-like protein.

21 January 2018

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Differential expression of Rac1 identifies its target genes and its contribution to progression of colorectal cancer

21 January 2018

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Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring

21 January 2018

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Actin and myosin as transcription factors

21 January 2018

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RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding

21 January 2018

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Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies

21 January 2018

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Molecular anatomy of a speckle

21 January 2018

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Implication of a small GTPase Rac1 in the activation of c-Jun N-terminal kinase and heat shock factor in response to heat shock

21 January 2018

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21 January 2018

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Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy

21 January 2018

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The nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4, interacts with core histones

21 January 2018

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Multiple actin-related proteins of Saccharomyces cerevisiae are present in the nucleus

21 January 2018

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Correlation between chromatin association and transcriptional regulation for the Act3p/Arp4 nuclear actin-related protein of Saccharomyces cerevisiae

21 January 2018

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Direct visualization of a protein nuclear architecture

21 January 2018

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Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation.

21 January 2018

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Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

21 January 2018

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

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Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II.

21 January 2018

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From transcription to transport: emerging roles for nuclear myosin I.

21 January 2018

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Multiple roles for emerin: implications for Emery-Dreifuss muscular dystrophy

21 January 2018

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An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.

21 January 2018

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Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane

21 January 2018

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Atomic model of the actin filament

21 January 2018

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A role for beta-actin in RNA polymerase III transcription

21 January 2018

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Nuclear localisation of the G-actin sequestering peptide thymosin beta4.

21 January 2018

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Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 January 2018

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Cellular mechanotransduction: putting all the pieces together again

21 January 2018

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21 January 2018

Nuclear lipid signalling

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Tracking down the different forms of nuclear actin

21 January 2018

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Recovery of gel-separated proteins for in-solution digestion and mass spectrometry

21 January 2018

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Atomic structure of the actin:DNase I complex

21 January 2018

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Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates.

21 January 2018

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p54(nrb) associates with the 5' splice site within large transcription/splicing complexes.

21 January 2018

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21 January 2018

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Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors

21 January 2018

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hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation

21 January 2018

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Interferon-gamma-induced expressions of heat shock protein 60 and heat shock protein 10 in C6 astroglioma cells: identification of the signal transducers and activators of transcription 3-binding site in bidirectional promoter

21 January 2018

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Rev-dependent association of the intron-containing HIV-1 gag mRNA with the nuclear actin bundles and the inhibition of its nucleocytoplasmic transport by latrunculin-B.

21 January 2018

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Connecting the dots between septins and the DNA damage checkpoint.

21 January 2018

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Actin- and protein-4.1-containing filaments link nuclear pore complexes to subnuclear organelles in Xenopus oocyte nuclei.

21 January 2018

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The role of profilin in actin polymerization and nucleotide exchange.

21 January 2018

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Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

21 January 2018

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Two distinct domains of protein 4.1 critical for assembly of functional nuclei in vitro

21 January 2018

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Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

21 January 2018

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Actin and hnRNP U cooperate for productive transcription by RNA polymerase II.

21 January 2018

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Chromatin dynamics and gene positioning

21 January 2018

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Active and inactive genes localize preferentially in the periphery of chromosome territories

21 January 2018

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Nuclear speckles: a model for nuclear organelles

21 January 2018

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Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions

21 January 2018

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Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.

21 January 2018

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The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

21 January 2018

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Cofilin promotes rapid actin filament turnover in vivo

21 January 2018

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The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68

21 January 2018

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Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope

21 January 2018

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Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

21 January 2018

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Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins

21 January 2018

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Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

21 January 2018

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Individual interphase chromosome domains revealed by in situ hybridization

21 January 2018

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Nucleoplasmic beta-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations.

21 January 2018

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Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex

21 January 2018

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Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links

21 January 2018

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Nuclear actin-related proteins as epigenetic regulators of development

21 January 2018

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Changes of G-actin localisation in the mitotic spindle region or nucleus during mitosis and after heat shock: a histochemical study of G-actin in various cell lines with fluorescent labelled vitamin D-binding protein.

21 January 2018

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Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

21 January 2018

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Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling

21 January 2018

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Actin in transcription and transcription regulation.

21 January 2018

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Actin dynamics control SRF activity by regulation of its coactivator MAL

21 January 2018

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Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro

21 January 2018

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Beyond the sequence: cellular organization of genome function

21 January 2018

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Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes

21 January 2018

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Rac1 is required for cell proliferation and G2/M progression.

21 January 2018

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Sequence and comparative genomic analysis of actin-related proteins

21 January 2018

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Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus

21 January 2018

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Cofilin is a component of intranuclear and cytoplasmic actin rods induced in cultured cells

21 January 2018

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A CH domain-containing N terminus in NuMA?

21 January 2018

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Evidence for the presence of myosin I in the nucleus

21 January 2018

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Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules

21 January 2018

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The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA.

21 January 2018

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Vertebrate Arp6, a novel nuclear actin-related protein, interacts with heterochromatin protein 1.

21 January 2018

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Nuclear actin and actin-related proteins in chromatin remodeling.

21 January 2018

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The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope

21 January 2018

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Rac1 contributes to maximal activation of STAT1 and STAT3 in IFN-gamma-stimulated rat astrocytes

21 January 2018

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As functional nuclear actin comes into view, is it globular, filamentous, or both?

21 January 2018

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Actin in the nucleus: what form and what for?

21 January 2018

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Nuclear actin extends, with no contraction in sight

21 January 2018

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Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells

21 January 2018

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Chromatin remodelling and transcription: be-WICHed by nuclear myosin 1.

21 January 2018

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Molecular functions of nuclear actin in transcription

21 January 2018

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Actin bound to the heterogeneous nuclear ribonucleoprotein hrp36 is associated with Balbiani ring mRNA from the gene to polysomes.

21 January 2018

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Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins

21 January 2018

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An actin-ribonucleoprotein interaction is involved in transcription by RNA polymerase II.

21 January 2018

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A myosin I isoform in the nucleus

21 January 2018

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Subunits of the yeast SWI/SNF complex are members of the actin-related protein (ARP) family

21 January 2018

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Nuclear actin and myosin I are required for RNA polymerase I transcription.

21 January 2018

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Cellular motility driven by assembly and disassembly of actin filaments

21 January 2018

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Actin' together: serum response factor, its cofactors and the link to signal transduction

21 January 2018

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Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor

21 January 2018

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Myosin Va phosphorylated on Ser1650 is found in nuclear speckles and redistributes to nucleoli upon inhibition of transcription

21 January 2018

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Searching for a function for nuclear actin.

21 January 2018

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Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex

21 January 2018

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Inducible clustering of membrane-targeted SH3 domains of the adaptor protein Nck triggers localized actin polymerization

21 January 2018

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The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

21 January 2018

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Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

21 January 2018

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

21 January 2018

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Reversible translocation of cytoplasmic actin into the nucleus caused by dimethyl sulfoxide

21 January 2018

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Conformation-specific antibodies reveal distinct actin structures in the nucleus and the cytoplasm

21 January 2018

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PSF and p54(nrb)/NonO--multi-functional nuclear proteins

21 January 2018

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A chromatin remodelling complex involved in transcription and DNA processing.

21 January 2018

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Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

21 January 2018

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Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence

21 January 2018

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Regulation of STAT3 by direct binding to the Rac1 GTPase

21 January 2018

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The growing pre-mRNA recruits actin and chromatin-modifying factors to transcriptionally active genes

21 January 2018

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Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links

21 January 2018

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Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes

21 January 2018

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Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90.

21 January 2018

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Sustained activation of N-WASP through phosphorylation is essential for neurite extension

21 January 2018

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The nuclear actin-related proteins Arp7 and Arp9: a dimeric module that cooperates with architectural proteins for chromatin remodeling

21 January 2018

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Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes.

21 January 2018

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Differential regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2.

21 January 2018

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A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix

21 January 2018

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The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins

21 January 2018

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At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide

21 January 2018

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Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

21 January 2018

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The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation

21 January 2018

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Actin in transcription. Actin is required for transcription by all three RNA polymerases in the eukaryotic cell nucleus

21 January 2018

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Nuclear myosin VI enhances RNA polymerase II-dependent transcription

21 January 2018

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Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein

21 January 2018

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Genetic ablation of Rac1 in cartilage results in chondrodysplasia.

21 January 2018

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Actin-based modeling of a transcriptionally competent nuclear substructure induced by transcription inhibition

21 January 2018

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Diversity and specialization of mammalian SWI/SNF complexes

21 January 2018

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Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment

21 January 2018

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The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly

21 January 2018

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The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences

21 January 2018

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Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.

21 January 2018

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Rac1 signaling stimulates N-cadherin expression, mesenchymal condensation, and chondrogenesis

21 January 2018

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Effects of profilin and thymosin beta4 on the critical concentration of actin demonstrated in vitro and in cell extracts with a novel direct assay

21 January 2018

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Profilin: emerging concepts and lingering misconceptions

21 January 2018

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Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription

21 January 2018

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Spectrin repeat proteins in the nucleus.

21 January 2018

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Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus

21 January 2018

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Death in the third dimension: apoptosis regulation and tissue architecture

21 January 2018

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Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities

21 January 2018

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Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells

21 January 2018

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Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle

21 January 2018

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Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity

21 January 2018

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Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling

21 January 2018

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Filamins in cardiovascular development

21 January 2018

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Nuclear bodies and compartments: functional roles and cellular signalling in health and disease

21 January 2018

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Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei

21 January 2018

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Nuclear structure in cancer cells

21 January 2018

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Local gene density predicts the spatial position of genetic loci in the interphase nucleus

21 January 2018

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Topology of genes and nontranscribed sequences in human interphase nuclei

21 January 2018

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Actin's many actions start at the genes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O08-133

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20 August 2017

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