(Q37402403)

20 August 2017

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title

Molecular targets for cancer chemoprevention (English)

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20 August 2017

2

John V Heymach

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20 August 2017

4

Scott M Lippman

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20 August 2017

William N William

1

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20 August 2017

Edward S Kim

series ordinal

3

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20 August 2017

publication date

1 March 2009

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Nature Reviews Drug Discovery

20 August 2017

published in

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20 August 2017

volume

8

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20 August 2017

issue

3

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20 August 2017

page(s)

213-225

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https://scigraph.springernature.com/pub.10.1038/nrd2663

20 August 2017

exact match

0 references

cites work

Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward

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Celecoxib for the prevention of colorectal adenomatous polyps

31 March 2020

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Celecoxib for the prevention of sporadic colorectal adenomas

31 March 2020

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A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas.

31 March 2020

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Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

31 March 2020

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Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial

31 March 2020

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The influence of finasteride on the development of prostate cancer

31 March 2020

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Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

31 March 2020

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A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

31 March 2020

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A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

31 March 2020

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Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy

31 March 2020

1 reference

Effects of cigarette smoke on the human airway epithelial cell transcriptome

31 March 2020

1 reference

Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer

31 March 2020

1 reference

Genetic clonal diversity predicts progression to esophageal adenocarcinoma

31 March 2020

1 reference

Projecting individualized probabilities of developing breast cancer for white females who are being examined annually

31 March 2020

1 reference

An expanded risk prediction model for lung cancer

31 March 2020

1 reference

A risk model for prediction of lung cancer

31 March 2020

1 reference

Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial.

31 March 2020

1 reference

Validation of the Gail et al. model of breast cancer risk prediction and implications for chemoprevention

31 March 2020

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Stratification of breast cancer risk in women with atypia: a Mayo cohort study

31 March 2020

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Cancer risk prediction models: a workshop on development, evaluation, and application

31 March 2020

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Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors

31 March 2020

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Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort

31 March 2020

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A prediction model for lung cancer diagnosis that integrates genomic and clinical features

31 March 2020

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NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma

31 March 2020

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Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer

31 March 2020

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Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group

31 March 2020

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Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases

31 March 2020

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Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions

31 March 2020

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Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial

31 March 2020

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Effect of human papillomavirus 16/18 L1 viruslike particle vaccine among young women with preexisting infection: a randomized trial

31 March 2020

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Clonal integration of a polyomavirus in human Merkel cell carcinoma

31 March 2020

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Understanding microbe-induced cancers

31 March 2020

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Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-helicobacter pylori therapy

31 March 2020

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Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions

31 March 2020

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31 March 2020

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Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity

31 March 2020

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Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy

31 March 2020

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Immunoprevention of cancer

31 March 2020

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13-cis-retinoic acid in the treatment of oral leukoplakia

31 March 2020

1 reference

Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck

31 March 2020

1 reference

Prevention of second primary tumors with isotretinoin in patients with squamous cell carcinoma of the head and neck: long-term follow-up

31 March 2020

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Comparison of low-dose isotretinoin with beta carotene to prevent oral carcinogenesis

31 March 2020

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Low-dose isotretinoin versus beta-carotene to prevent oral carcinogenesis: long-term follow-up

31 March 2020

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Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin.

31 March 2020

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Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

31 March 2020

1 reference

First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial

31 March 2020

1 reference

Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial

31 March 2020

1 reference

Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial

31 March 2020

1 reference

Overview of the main outcomes in breast-cancer prevention trials

31 March 2020

1 reference

Long-term results of tamoxifen prophylaxis for breast cancer--96-month follow-up of the randomized IBIS-I trial

31 March 2020

1 reference

Patient reluctance toward tamoxifen use for breast cancer primary prevention

31 March 2020

1 reference

Selective estrogen-receptor modulators for primary prevention of breast cancer

31 March 2020

1 reference

The prevention of prostate cancer--the dilemma continues

31 March 2020

1 reference

Finasteride decreases the risk of prostatic intraepithelial neoplasia.

31 March 2020

1 reference

Pathologic characteristics of cancers detected in The Prostate Cancer Prevention Trial: implications for prostate cancer detection and chemoprevention

31 March 2020

1 reference

Finasteride and high-grade prostate cancer in the Prostate Cancer Prevention Trial.

31 March 2020

1 reference

Finasteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modeling approach

31 March 2020

1 reference

Estimating rates of true high-grade disease in the prostate cancer prevention trial

31 March 2020

1 reference

High-grade prostate cancer and the prostate cancer prevention trial

31 March 2020

1 reference

Implications of the prostate cancer prevention trial: a decision analysis model of survival outcomes

31 March 2020

1 reference

Reducing the "risk" of chemoprevention: defining and targeting high risk--2005 AACR Cancer Research and Prevention Foundation Award Lecture

31 March 2020

1 reference

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis

31 March 2020

1 reference

A randomized trial of aspirin to prevent colorectal adenomas

31 March 2020

1 reference

Aspirin and folic acid for the prevention of recurrent colorectal adenomas

31 March 2020

1 reference

A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer

31 March 2020

1 reference

Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies

31 March 2020

1 reference

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

31 March 2020

1 reference

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

31 March 2020

1 reference

Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention

31 March 2020

1 reference

Risks and Benefits of Celecoxib to Prevent Recurrent Adenomas

31 March 2020

1 reference

The role of selective estrogen receptor modulators in the prevention of breast cancer: comparison of the clinical trials

31 March 2020

1 reference

Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis

31 March 2020

1 reference

Aspirin and the risk of colorectal cancer in relation to the expression of COX-2.

31 March 2020

1 reference

Aspirin and colon cancer--targeting prevention?

31 March 2020

1 reference

The convergence of cancer prevention and therapy in early-phase clinical drug development

31 March 2020

1 reference

The convergent development of molecular-targeted drugs for cancer treatment and prevention

31 March 2020

1 reference

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

31 March 2020

1 reference

Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

31 March 2020

1 reference

Targeting HIF-1 for cancer therapy

31 March 2020

1 reference

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms

31 March 2020

1 reference

Pseudohypoxic pathways in renal cell carcinoma

31 March 2020

1 reference

Molecular biology of renal cell cancer and the identification of therapeutic targets

31 March 2020

1 reference

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

31 March 2020

1 reference

Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

31 March 2020

1 reference

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

31 March 2020

1 reference

Variations in lung cancer risk among smokers.

31 March 2020

1 reference

Aberrant crypt foci in the adenoma prevention with celecoxib trial

31 March 2020

1 reference

31 March 2020

1 reference

Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

31 March 2020

1 reference

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

31 March 2020

1 reference

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients

31 March 2020

1 reference

Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

31 March 2020

1 reference

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

31 March 2020

1 reference

Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells

31 March 2020

1 reference

Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin

31 March 2020

1 reference

Effects of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on human small airway epithelial cells and the protective effects of myo-inositol

31 March 2020

1 reference

Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras

31 March 2020

1 reference

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

31 March 2020

1 reference

Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice

31 March 2020

1 reference

Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer

31 March 2020

1 reference

Combinatorial chemoprevention of intestinal neoplasia

31 March 2020

1 reference

Combination chemoprevention of cancer

31 March 2020

1 reference

Combinations for cancer prevention

31 March 2020

1 reference

Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial

31 March 2020

1 reference

Dose de-escalation chemoprevention trial of alpha-difluoromethylornithine in patients with colon polyps

31 March 2020

1 reference

Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention

31 March 2020

1 reference

Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

31 March 2020

1 reference

Ornithine decarboxylase G316A genotype is prognostic for colorectal adenoma recurrence and predicts efficacy of aspirin chemoprevention

31 March 2020

1 reference

Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene

31 March 2020

1 reference

Cyclin D1 and cancer development in laryngeal premalignancy patients

31 March 2020

1 reference

Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy

31 March 2020

1 reference

Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study

31 March 2020

1 reference

12 December 2020

Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development

1 reference

12 December 2020

Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.

1 reference

12 December 2020

Predicting cancer development in oral leukoplakia: ten years of translational research

1 reference

12 December 2020

Anti-retinoic acid (RA) antibody binding to human premalignant oral lesions, which occurs less frequently than binding to normal tissue, increases after 13-cis-RA treatment in vivo and is related to RA receptor beta expression

1 reference

12 December 2020

Cancer chemoprevention in the 21st century: genetics, risk modeling, and molecular targets.

1 reference

12 December 2020

Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)

1 reference

12 December 2020

Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial

1 reference

12 December 2020

Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies

1 reference

12 December 2020

Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues

1 reference

12 December 2020

Chemoprevention of colon carcinogenesis by dietary administration of piroxicam, alpha-difluoromethylornithine, 16 alpha-fluoro-5-androsten-17-one, and ellagic acid individually and in combination

1 reference

12 December 2020

3p14 and 9p21 loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites

1 reference

12 December 2020

Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia.

1 reference

12 December 2020

Inhibition of intestinal carcinogenesis in rats: effect of difluoromethylornithine with piroxicam or fish oil

1 reference

12 December 2020

Cancer prevention science and practice

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRD2663

1 reference

release_fb2qdgo6bjbidcpottporpfw2u

20 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/fb2qdgo6bjbidcpottporpfw2u

24 November 2022

mapped directly with Wikidata item

1 reference