(Q37402798)

English

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.

scientific article published on 13 July 2009

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scholarly article

1 reference

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2 February 2020

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis (English)

1 reference

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2 February 2020

5

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2 February 2020

Reynold A Panettieri

6

object named as

Reynold A Panettieri

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2 February 2020

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Omar Tliba

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2 February 2020

Vera P Krymskaya

7

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Vera P Krymskaya

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2 February 2020

author name string

Elena A Goncharova

1

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2 February 2020

Dmitry A Goncharov

2

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2 February 2020

Gautam Damera

3

1 reference

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2 February 2020

publication date

13 July 2009

1 reference

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2 February 2020

Molecular Pharmacology

1 reference

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2 February 2020

76

1 reference

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2 February 2020

4

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2 February 2020

766-777

1 reference

Europe PubMed Central

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1 reference

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Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis

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6 September 2017

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6 September 2017

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

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6 September 2017

Pulmonary lymphangioleiomyomatosis (LAM): progress and current challenges

1 reference

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mTOR and cancer: insights into a complex relationship

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6 September 2017

Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2

1 reference

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6 September 2017

Interferon-gamma-Jak-Stat signaling in pulmonary lymphangioleiomyomatosis and renal angiomyolipoma: a potential therapeutic target

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6 September 2017

Mechanisms of type-I- and type-II-interferon-mediated signalling

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6 September 2017

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

1 reference

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6 September 2017

Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment

1 reference

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6 September 2017

STAT proteins: From normal control of cellular events to tumorigenesis

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Renal carcinogenesis: genotype, phenotype and dramatype

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Association between a high-expressing interferon-gamma allele and a lower frequency of kidney angiomyolipomas in TSC2 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2769052

6 September 2017

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2769052

6 September 2017

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

1 reference

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Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines.

1 reference

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6 September 2017

Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells

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14 September 2017

Combination of a rapamycin analog (CCI-779) and interferon-gamma is more effective than single agents in treating a mouse model of tuberous sclerosis complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2769052

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Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway

1 reference

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Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression

1 reference

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2 September 2018

Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation

1 reference

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1 reference

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AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling.

1 reference

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Type I and type II interferons delay human neutrophil apoptosis via activation of STAT3 and up-regulation of cellular inhibitor of apoptosis 2.

1 reference

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1 reference

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2 September 2018

Alternative activation of STAT1 and STAT3 in response to interferon-gamma

1 reference

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2 September 2018

Shear flow attenuates serum-induced STAT3 activation in endothelial cells.

1 reference

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1 reference

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Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.

1 reference

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2 September 2018

Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19596836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19596836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19596836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.109.057042

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19596836%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19596836%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19596836%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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