(Q37403959)

20 August 2017

1 reference

title

Compartmentalization and regulation of insulin signaling to GLUT4 by the cytoskeleton (English)

1 reference

20 August 2017

0 references

1 reference

Craig A Eyster

1

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20 August 2017

Ann Louise Olson

series ordinal

2

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20 August 2017

publication date

1 January 2009

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20 August 2017

published in

Vitamins and Hormones

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20 August 2017

volume

80

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20 August 2017

page(s)

193-215

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Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin

20 August 2017

cites work

1 reference

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7 January 2021

Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action.

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7 January 2021

Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific in

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7 January 2021

GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin

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7 January 2021

Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking

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7 January 2021

The mechanisms of vesicle budding and fusion

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7 January 2021

Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c

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7 January 2021

Unconventional myosin Myo1c promotes membrane fusion in a regulated exocytic pathway

1 reference

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7 January 2021

14-3-3 proteins: a number of functions for a numbered protein

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Regulated transport of the glucose transporter GLUT4

1 reference

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7 January 2021

Targeting of the Akt/PKB kinase to the actin skeleton.

1 reference

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7 January 2021

Insulin signaling and the regulation of glucose transport.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Protective effect of phosphatidylinositol 4,5-bisphosphate against cortical filamentous actin loss and insulin resistance induced by sustained exposure of 3T3-L1 adipocytes to insulin

1 reference

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7 January 2021

Demonstration of differential quantitative requirements for NSF among multiple vesicle fusion pathways of GLUT4 using a dominant-negative ATPase-deficient NSF.

1 reference

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7 January 2021

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

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7 January 2021

Role of caveolin and caveolae in insulin signaling and diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin stimulates the entry of GLUT4 into the endosomal recycling pathway by a quantal mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Signaling mechanisms that regulate glucose transport

1 reference

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7 January 2021

PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle

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7 January 2021

The formation of an insulin-responsive vesicular cargo compartment is an early event in 3T3-L1 adipocyte differentiation

1 reference

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7 January 2021

A role for kinesin in insulin-stimulated GLUT4 glucose transporter translocation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Expression of constitutively active Akt/protein kinase B signals GLUT4 translocation in the absence of an intact actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Microtubule network is required for insulin signaling through activation of Akt/protein kinase B: evidence that insulin stimulates vesicle docking/fusion but not intracellular mobility

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

SNARE regulators: matchmakers and matchbreakers

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Characterization of insulin-responsive GLUT4 storage vesicles isolated from 3T3-L1 adipocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Protein kinase-zeta interacts with munc18c: role in GLUT4 trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

A specific dileucine motif is required for the GGA-dependent entry of newly synthesized insulin-responsive aminopeptidase into the insulin-responsive compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Minireview: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

SNAREs--engines for membrane fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Membrane fusion and exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

MUNC-ing around with insulin action.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Comparison of glucose-transporter-containing vesicles from rat fat and muscle tissues: evidence for a unique endosomal compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Isolation and characterization of the two major intracellular Glut4 storage compartments

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin-regulated release from the endosomal recycling compartment is regulated by budding of specialized vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Compartment ablation analysis of the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Functional studies in 3T3L1 cells support a role for SNARE proteins in insulin stimulation of GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Association of N-ethylmaleimide sensitive fusion (NSF) protein and soluble NSF attachment proteins-alpha and -gamma with glucose transporter-4-containing vesicles in primary rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Adipsin and the glucose transporter GLUT4 traffic to the cell surface via independent pathways in adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

1 reference

7 January 2021

Increased Insulin Sensitivity and Hypoinsulinemia in APS Knockout Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

RNAi-based analysis of CAP, Cbl, and CrkII function in the regulation of GLUT4 by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Role of IRS-1-GRB-2 complexes in insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Synip phosphorylation is required for insulin-stimulated Glut4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin-mediated GLUT4 translocation is dependent on the microtubule network

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin promotes formation of polymerized microtubules by a phosphatidylinositol 3-kinase-independent, actin-dependent pathway in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Actin filaments play a critical role in insulin-induced exocytotic recruitment but not in endocytosis of GLUT4 in isolated rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Intracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin action on GLUT4 traffic visualized in single 3T3-l1 adipocytes by using ultra-fast microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

VAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Translocation of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1 adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4 to clathrin lattices

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Synip phosphorylation does not regulate insulin-stimulated GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Autophosphorylation within insulin receptor .beta.-subunits can occur as an intramolecular process

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

The synaptic vesicle cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Phosphatidylinositol 3-kinase and the actin network are not required for the stimulation of glucose transport caused by mitochondrial uncoupling: comparison with insulin action

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Role of protein kinase B in insulin-regulated glucose uptake.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

The glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Rab proteins as membrane organizers

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

Analysis of insulin signalling by RNAi-based gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900608-0

7 January 2021

10.1016/S0083-6729(08)00608-0

Identifiers

DOI

1 reference

20 August 2017

1 reference