(Q42815361)

7 November 2017

title

Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes (English)

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7 November 2017

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Tetsuya Yamada

1

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7 November 2017

Hideki Katagiri

2

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7 November 2017

Tomoichiro Asano

3

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7 November 2017

Masatoshi Tsuru

4

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7 November 2017

Kouichi Inukai

5

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7 November 2017

Hiraku Ono

6

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7 November 2017

Tatsuhiko Kodama

7

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7 November 2017

Masatoshi Kikuchi

8

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7 November 2017

Yoshitomo Oka

9

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7 November 2017

publication date

1 June 2002

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American Journal of Physiology - Endocrinology and Metabolism

7 November 2017

published in

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7 November 2017

volume

282

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7 November 2017

issue

6

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7 November 2017

page(s)

E1385-94

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

7 November 2017

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PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

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Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms.

21 January 2018

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Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

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CAP defines a second signalling pathway required for insulin-stimulated glucose transport

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Stimulation of protein phosphatase-1 activity by insulin in rat adipocytes. Evaluation of the role of mitogen-activated protein kinase pathway

21 January 2018

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Intracellular signalling: PDK1--a kinase at the hub of things

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Inhibition of glycogen synthase kinase-3 by insulin in cultured human skeletal muscle myoblasts

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The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

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Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

21 January 2018

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Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

21 January 2018

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Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells

21 January 2018

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Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

21 January 2018

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Potential role of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in insulin-stimulated glucose transporter 4 translocation in adipocytes

21 January 2018

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Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

21 January 2018

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Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

21 January 2018

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Roles of PI 3-kinase and Ras on insulin-stimulated glucose transport in 3T3-L1 adipocytes

21 January 2018

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Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes

21 January 2018

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Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

21 January 2018

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes

21 January 2018

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Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

21 January 2018

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

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Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells.

21 January 2018

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Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: insulin activation of type 1 phosphatase

21 January 2018

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p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00486.2001

Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells

21 January 2018

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Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00486.2001

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake

21 January 2018

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The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

21 January 2018

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Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes

21 January 2018

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Potential role of protein kinase B in glucose transporter 4 translocation in adipocytes

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00486.2001

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

21 January 2018

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Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

21 January 2018

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Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00486.2001

Activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00486.2001

3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells

21 January 2018

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Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

21 January 2018

1 reference

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10.1152/AJPENDO.00486.2001

21 January 2018

Identifiers

DOI

1 reference

7 November 2017

1 reference