(Q37408442)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19463001%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease (English)

1 reference

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28 January 2020

0 references

4

1 reference

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28 January 2020

Frederick S Buckner

11

1 reference

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28 January 2020

12

Michael H Gelb

1 reference

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28 January 2020

6

Christophe L M J Verlinde

1 reference

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Praveen Kumar Suryadevara

28 January 2020

1

object named as

Praveen Kumar Suryadevara

1 reference

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28 January 2020

9

Wesley C Van Voorhis

1 reference

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28 January 2020

James Alexander Kraus

7

object named as

James M Kraus

1 reference

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28 January 2020

2

Srinivas Olepu

1 reference

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28 January 2020

3

Jeffrey W Lockman

1 reference

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28 January 2020

author name string

Mandana Karimi

5

1 reference

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28 January 2020

Jan Schoepe

8

1 reference

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28 January 2020

Andrew D Hamilton

10

1 reference

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28 January 2020

language of work or name

English

0 references

publication date

1 June 2009

1 reference

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Journal of Medicinal Chemistry

28 January 2020

published in

1 reference

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28 January 2020

volume

52

1 reference

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28 January 2020

issue

12

1 reference

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28 January 2020

page(s)

3703-3715

1 reference

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Rational modification of a candidate cancer drug for use against Chagas disease

28 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Sterol 14-demethylase inhibitors for Trypanosoma cruzi infections.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

2-Oxo-tetrahydro-1,8-naphthyridines as selective inhibitors of malarial protein farnesyltransferase and as anti-malarials

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

The Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Specific chemotherapy of Chagas disease: controversies and advances

6 September 2017

1 reference

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Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

6 September 2017

1 reference

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Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Probing the hydrophobic pocket of farnesyltransferase: aromatic substitution of CAAX peptidomimetics leads to highly potent inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Design and synthesis of potent nonpeptidic farnesyltransferase inhibitors based on a terphenyl scaffold.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Sensitive detection and schizodeme classification of Trypanosoma cruzi cells by amplification of kinetoplast minicircle DNA sequences: use in diagnosis of Chagas' disease

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Polymerase chain reaction amplification of Trypanosoma cruzi kinetoplast minicircle DNA isolated from whole blood lysates: diagnosis of chronic Chagas' disease

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

In vitro and in vivo activities of ravuconazole on Trypanosoma cruzi, the causative agent of Chagas disease

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

Trypanosoma cruzi: optimization of polymerase chain reaction for detection in human blood

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771698

2 September 2018

Identifiers

DOI

10.1021/JM900030H

1 reference

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28 January 2020

1 reference

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28 January 2020

1 reference