(Q37409283)

20 August 2017

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title

Harnessing innate and adaptive immunity for adoptive cell therapy of renal cell carcinoma (English)

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20 August 2017

4

Christine S Falk

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20 August 2017

Christiane Geiger

1

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20 August 2017

Elfriede Nössner

2

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20 August 2017

Bernhard Frankenberger

3

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20 August 2017

Heike Pohla

5

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20 August 2017

Dolores J Schendel

6

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20 August 2017

language of work or name

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7 March 2009

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Journal of Molecular Medicine

20 August 2017

published in

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20 August 2017

volume

87

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20 August 2017

issue

6

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20 August 2017

page(s)

595-612

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https://scigraph.springernature.com/pub.10.1007/s00109-009-0455-2

20 August 2017

exact match

0 references

cites work

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Questionable relevance of gamma delta T lymphocytes in renal cell carcinoma

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Characterization of a novel nonclassical T cell clone with broad reactivity against human renal cell carcinomas

21 January 2018

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Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens.

21 January 2018

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CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells

21 January 2018

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12 December 2020

Renal cell carcinoma-associated antigen G250 encodes a naturally processed epitope presented by human leukocyte antigen-DR molecules to CD4(+) T lymphocytes

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12 December 2020

Role of chemokines in the biology of natural killer cells

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12 December 2020

Monoclonal T-cell receptors: new reagents for cancer therapy.

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12 December 2020

Innate lymphocyte and dendritic cell cross-talk: a key factor in the regulation of the immune response.

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12 December 2020

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

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12 December 2020

Human renal-cell carcinoma tissue contains dendritic cells

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12 December 2020

Potential of human gammadelta T lymphocytes for immunotherapy of cancer

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12 December 2020

Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma

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12 December 2020

Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity

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12 December 2020

Natural killer cell alloreactivity in allogeneic hematopoietic transplantation.

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12 December 2020

Lymphocyte therapy of renal cell carcinoma

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12 December 2020

Allogeneic stem cell transplantation for patients with metastatic renal cell carcinoma

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12 December 2020

Adoptive cellular therapy.

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12 December 2020

Selective lysis of autologous tumor cells by recurrent gamma delta tumor-infiltrating lymphocytes from renal carcinoma

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12 December 2020

Transcriptional program associated with IFN-alpha response of renal cell carcinoma.

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12 December 2020

MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.

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12 December 2020

Interferon-alpha (IFN-alpha)-conditioned DC preferentially stimulate type-1 and limit Treg-type in vitro T-cell responses from RCC patients.

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12 December 2020

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

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12 December 2020

All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients

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12 December 2020

The role of carbonic anhydrase IX overexpression in kidney cancer

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12 December 2020

Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study.

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12 December 2020

Designer T cells by T cell receptor replacement.

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12 December 2020

What's past is prologue: lessons learned and the need for further development of allogeneic hematopoietic stem cell transplantation for renal cell carcinoma

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12 December 2020

Loss of CTL function among high-avidity tumor-specific CD8+ T cells following tumor infiltration

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12 December 2020

Spontaneous regression of pulmonary metastases from renal cell carcinoma after radio frequency ablation of primary tumor: an in situ tumor vaccine?

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Disease stage variation in CD4+ and CD8+ T-cell reactivity to the receptor tyrosine kinase EphA2 in patients with renal cell carcinoma.

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12 December 2020

Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes

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12 December 2020

Monocytes and neutrophils as 'bad guys' for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma--results from a randomised phase II trial

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12 December 2020

TCR-independent cytokine stimulation induces non-MHC-restricted T cell activity and is negatively regulated by HLA class I

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12 December 2020

Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells.

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12 December 2020

Interleukin-12 and the regulation of innate resistance and adaptive immunity

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12 December 2020

Characterization of fresh (uncultured) tumour-infiltrating lymphocytes (TIL) and TIL-derived T cell lines from patients with renal cell carcinoma

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12 December 2020

Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors

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12 December 2020

Toward an understanding of NKT cell biology: progress and paradoxes

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12 December 2020

Immune suppression in renal cell carcinoma

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12 December 2020

Gene transfer of human interferon gamma complementary DNA into a renal cell carcinoma line enhances MHC-restricted cytotoxic T lymphocyte recognition but suppresses non-MHC-restricted effector cell activity

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12 December 2020

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

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12 December 2020

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12 December 2020

An alternative open reading frame of the human macrophage colony-stimulating factor gene is independently translated and codes for an antigenic peptide of 14 amino acids recognized by tumor-infiltrating CD8 T lymphocytes

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12 December 2020

Inhibitory effect of RNA pool complexity on stimulatory capacity of RNA-pulsed dendritic cells

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12 December 2020

Dendritic cell vaccine strategies for renal cell carcinoma

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12 December 2020

Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex.

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12 December 2020

Human renal cell carcinoma antigen-specific CTLs: antigen-driven selection and long-term persistence in vivo.

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12 December 2020

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

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12 December 2020

Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer

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12 December 2020

Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining

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12 December 2020

Small cell lung cancer and targeted therapies.

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12 December 2020

Activation of tumor-specific CD8+ T Cells after intratumoral Ad5-TRAIL/CpG oligodeoxynucleotide combination therapy.

1 reference

12 December 2020

Minimal recruitment and activation of dendritic cells within renal cell carcinoma

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12 December 2020

The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments

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12 December 2020

Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas.

1 reference

12 December 2020

Restriction of the T-cell repertoire in tumor-infiltrating lymphocytes from nine patients with renal-cell carcinoma. Relevance of the CDR3 length analysis for the identification of in situ clonal T-cell expansions

1 reference

12 December 2020

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I

1 reference

12 December 2020

Immune recognition of a human renal cancer antigen through post-translational protein splicing.

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12 December 2020

Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers

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12 December 2020

Tumor infiltrating dendritic cells predict treatment response to immmunotherapy in patients with metastatic renal cell carcinoma

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12 December 2020

Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer

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12 December 2020

DC-NK cell cross talk as a novel CD4+ T-cell-independent pathway for antitumor CTL induction

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12 December 2020

A mutated HLA-A2 molecule recognized by autologous cytotoxic T lymphocytes on a human renal cell carcinoma

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12 December 2020

Protein expression profiles in renal cell carcinoma: staging, prognosis, and patient selection for clinical trials

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12 December 2020

Identification of tumour-associated T-cell epitopes for vaccine development

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12 December 2020

Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells

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12 December 2020

Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma

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12 December 2020

Analysis of NK cells and chemokine receptors in tumor infiltrating CD4 T lymphocytes in human renal carcinomas.

1 reference

12 December 2020

Peripheral blood neutrophils as independent immunologic predictor of response and long-term survival upon immunotherapy in metastatic renal-cell carcinoma

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12 December 2020

Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.

1 reference

12 December 2020

Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

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12 December 2020

Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma

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12 December 2020

Clinical applications of natural killer T cell-based immunotherapy for cancer

1 reference

12 December 2020

Characterisation of gamma delta T cells in renal cell carcinoma patients by polymerase chain reaction analysis of T cell receptor transcripts

1 reference

12 December 2020

Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity

1 reference

12 December 2020

The renal cell carcinoma-associated antigen G250 encodes a human leukocyte antigen (HLA)-A2.1-restricted epitope recognized by cytotoxic T lymphocytes

1 reference

12 December 2020

Combined natural killer T-cell based immunotherapy eradicates established tumors in mice

1 reference

12 December 2020

Distinct functional lineages of human V(alpha)24 natural killer T cells

1 reference

12 December 2020

Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia

1 reference

12 December 2020

Minor histocompatibility antigens: from transplantation problems to therapy of cancer

1 reference

12 December 2020

Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma.

1 reference

12 December 2020

In vivo description of dendritic cells in human renal cell carcinoma

1 reference

12 December 2020

Cross-presentation of disialoganglioside GD3 to natural killer T cells

1 reference

12 December 2020

Preliminary analysis of patients with progressive renal cell carcinoma vaccinated with CA9-peptide-pulsed mature dendritic cells

1 reference

12 December 2020

Tolerogenic dendritic cells

1 reference

12 December 2020

Perspectives of gammadelta T cells in tumor immunology

1 reference

12 December 2020

In vivo local expansion of clonal T cell subpopulations in renal cell carcinoma.

1 reference

12 December 2020

Flow cytometric analysis of tumour-infiltrating lymphocytes in patients with renal cell carcinoma

1 reference

12 December 2020

The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma

1 reference

12 December 2020

Natural killer T cell-mediated antitumor immune responses and their clinical applications

1 reference

12 December 2020

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

1 reference

12 December 2020

Multicenter, randomized, phase III trial of CD8(+) tumor-infiltrating lymphocytes in combination with recombinant interleukin-2 in metastatic renal cell carcinoma

1 reference

12 December 2020

CD4 regulatory T cells in human cancer pathogenesis

1 reference

12 December 2020

Allogeneic hematopoietic cell transplantation as immunotherapy for solid tumors: current status and future directions

1 reference

12 December 2020

Induction and clonal expansion of tumor-specific cytotoxic T lymphocytes from renal cell carcinoma patients after stimulation with autologous dendritic cells loaded with tumor cells.

1 reference

12 December 2020

High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006.

1 reference

12 December 2020

GM2 expression in renal cell carcinoma: potential role in tumor-induced T-cell dysfunction

1 reference

12 December 2020

CD8+ cytotoxic T lymphocytes isolated from allogeneic healthy donors recognize HLA class Ia/Ib-associated renal carcinoma antigens with ubiquitous or restricted tissue expression

1 reference

12 December 2020

A function for interleukin 2 in Foxp3-expressing regulatory T cells

1 reference

12 December 2020

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

1 reference

12 December 2020

Renal cell carcinoma-infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes

1 reference

12 December 2020

Ex vivo generation and expansion of anti-tumor cytotoxic T-cell lines derived from patients or their HLA-identical sibling.

1 reference

12 December 2020

Regression of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell Transplantation

1 reference

12 December 2020

Dendritic cells in a mature age.

1 reference

12 December 2020

Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: toxicity, clinical response, and immunological response to minor histocompatibility antigens

1 reference

12 December 2020

Minor histocompatibility antigens as targets for immunotherapy using allogeneic immune reactions.

1 reference

12 December 2020

Type I interferons as regulators of the differentiation/activation of human dendritic cells: methods for the evaluation of IFN-induced effects.

1 reference

12 December 2020

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

1 reference

12 December 2020

Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells

1 reference

12 December 2020

Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma

1 reference

12 December 2020

Prognostic significance of tumor infiltrating natural killer cells subset CD57 in patients with squamous cell lung cancer.

1 reference

12 December 2020

Gamma /delta T cells provide innate immunity against renal cell carcinoma

1 reference

12 December 2020

Phenotype Analysis of Tumour-infiltrating Lymphocytes and Lymphocytes in Peripheral Blood in Patients with Renal Carcinoma.

1 reference

12 December 2020

Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy

1 reference

12 December 2020

A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription

1 reference

12 December 2020

Cellular and molecular analyses of major histocompatibility complex (MHC) restricted and non-MHC-restricted effector cells recognizing renal cell carcinomas: problems and perspectives for immunotherapy

1 reference

12 December 2020

MHC class-II molecules and autoimmunity

1 reference

12 December 2020

Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid

1 reference

12 December 2020

The biology of NKT cells

1 reference

12 December 2020

Clinical responses following nonmyeloablative allogeneic stem cell transplantation for renal cell carcinoma are associated with expansion of CD8+ IFN-gamma-producing T cells

1 reference

12 December 2020

Clinical effects of tumor-associated macrophages and dendritic cells on renal cell carcinoma

1 reference

12 December 2020

Retaliation against tumor cells showing aberrant HLA expression using lymphokine activated killer-derived T cells

1 reference

12 December 2020

A non-AUG-defined alternative open reading frame of the intestinal carboxyl esterase mRNA generates an epitope recognized by renal cell carcinoma-reactive tumor-infiltrating lymphocytes in situ

1 reference

12 December 2020

Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells

1 reference

12 December 2020

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

1 reference

12 December 2020

Tumor-specific lysis of human renal cell carcinomas by tumor-infiltrating lymphocytes. I. HLA-A2-restricted recognition of autologous and allogeneic tumor lines.

1 reference

12 December 2020

Regulating the immune response to tumours

1 reference

12 December 2020

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

1 reference

12 December 2020

Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy

1 reference

12 December 2020

Monitoring of WT1-specific cytotoxic T lymphocytes after allogeneic hematopoietic stem cell transplantation.

1 reference

12 December 2020

RNA transfer by electroporation into mature dendritic cells leading to reactivation of effector-memory cytotoxic T lymphocytes: a quantitative analysis

1 reference

12 December 2020

Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma

1 reference

12 December 2020

Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions

1 reference

12 December 2020

Heterozygosity or homozygosity for 2 HLA class II haplotypes predict favorable outcomes for renal cell carcinoma treated with cytokine therapy

1 reference

12 December 2020

Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70.

1 reference

12 December 2020

Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

1 reference

12 December 2020

Lysis of a broad range of epithelial tumour cells by human gamma delta T cells: involvement of NKG2D ligands and T-cell receptor- versus NKG2D-dependent recognition.

1 reference

12 December 2020

Inflammation, inflammatory cells and angiogenesis: decisions and indecisions

1 reference

12 December 2020

Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival

1 reference

12 December 2020

Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma

1 reference

12 December 2020

Large scale expansion of gamma 9 delta 2 T lymphocytes: Innacell gamma delta cell therapy product

1 reference

12 December 2020

CD27 expression discriminates between regulatory and non-regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells

1 reference

12 December 2020

Human tumor antigens for cancer vaccine development

1 reference

12 December 2020

Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy

1 reference

12 December 2020

A phase I trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma

1 reference

12 December 2020

A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma

1 reference

12 December 2020

gammadelta T cells: novel initiators of adaptive immunity.

1 reference

12 December 2020

Human neoplasms elicit multiple specific immune responses in the autologous host

1 reference

12 December 2020

Retroviral vectors for high-level transgene expression in T lymphocytes

1 reference

12 December 2020

Interferon in oncological practice: review of interferon biology, clinical applications, and toxicities

1 reference

12 December 2020

NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis

1 reference

12 December 2020

A hsp70-2 mutation recognized by CTL on a human renal cell carcinoma.

1 reference

12 December 2020

Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies

1 reference

12 December 2020

Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.

1 reference

12 December 2020

The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells

1 reference

12 December 2020

10.1007/S00109-009-0455-2

Identifiers

DOI

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20 August 2017

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