(Q37415565)

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Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly

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scholarly article

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Europe PubMed Central

PMC publication ID

20 August 2017

Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Timothy L Stemmler

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24217246%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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Alok Pandey

1

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6 June 2020

Donna M Gordon

2

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6 June 2020

Jayashree Pain

3

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6 June 2020

Andrew Dancis

5

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6 June 2020

Debkumar Pain

6

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6 June 2020

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11 November 2013

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20 August 2017

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14

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Journal of Biological Chemistry

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6 June 2020

288

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6 June 2020

52

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6 June 2020

36773-36786

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6 June 2020

describes a project that uses

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11 June 2022

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Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia

1 reference

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6 September 2017

Iron-sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia

1 reference

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6 September 2017

Identification of a Nfs1p-bound persulfide intermediate in Fe-S cluster synthesis by intact mitochondria

1 reference

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6 September 2017

The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism

1 reference

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6 September 2017

(IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer

1 reference

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6 September 2017

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease

1 reference

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6 September 2017

Mutation in the Fe-S scaffold protein Isu bypasses frataxin deletion

1 reference

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6 September 2017

Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.

1 reference

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6 September 2017

Proteomic approaches to the characterization of protein thiol modification

1 reference

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6 September 2017

Mitochondrial NADH kinase, Pos5p, is required for efficient iron-sulfur cluster biogenesis in Saccharomyces cerevisiae

1 reference

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6 September 2017

Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex

1 reference

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6 September 2017

Molecular details of the yeast frataxin-Isu1 interaction during mitochondrial Fe-S cluster assembly

1 reference

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6 September 2017

Frataxin and mitochondrial FeS cluster biogenesis.

1 reference

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6 September 2017

H2S signals through protein S-sulfhydration

1 reference

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6 September 2017

Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55.

1 reference

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6 September 2017

Pharmacotherapy for Friedreich ataxia

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6 September 2017

Drosophila frataxin: an iron chaperone during cellular Fe-S cluster bioassembly

1 reference

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6 September 2017

Monomeric yeast frataxin is an iron-binding protein

1 reference

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6 September 2017

The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria

1 reference

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6 September 2017

Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins

1 reference

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6 September 2017

Structure, function, and formation of biological iron-sulfur clusters

1 reference

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6 September 2017

Role of YHM1, encoding a mitochondrial carrier protein, in iron distribution of yeast

1 reference

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6 September 2017

An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

1 reference

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6 September 2017

Yeast mitochondrial protein, Nfs1p, coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution

1 reference

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6 September 2017

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

1 reference

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Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homologue

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6 September 2017

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

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6 September 2017

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

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6 September 2017

Pathology of the Heart in Friedreich's Ataxia: Review of the Literature and Report of One Case

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Human frataxin maintains mitochondrial iron homeostasis in Saccharomyces cerevisiae.

1 reference

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Binding of yeast frataxin to the scaffold for Fe-S cluster biogenesis, Isu

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Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1).

1 reference

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The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins

1 reference

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1 reference

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1 reference

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1 reference

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Identifiers

10.1074/JBC.M113.525857

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24217246%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24217246%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24217246%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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