(Q37418192)

20 August 2017

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title

Biomechanisms of cocaine-induced hepatocyte injury mediated by the formation of reactive metabolites (English)

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20 August 2017

U A Boelsterli

1

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20 August 2017

C Göldlin

series ordinal

2

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20 August 2017

publication date

1 January 1991

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20 August 2017

published in

Archives of Toxicology

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20 August 2017

volume

65

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20 August 2017

issue

5

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20 August 2017

page(s)

351-360

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Urinary excretion of cocaine, benzoylecgonine, and ecgonine methyl ester in humans.

20 August 2017

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Arylhydroxy metabolites of cocaine in the urine of cocaine users

21 January 2018

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Ethyl esters of arylhydroxy- and arylhydroxymethoxycocaines in the urines of simultaneous cocaine and ethanol users

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Hydroxymethoxybenzoylmethylecgonines: new metabolites of cocaine from human urine

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Cocaine metabolism: Cocaine and norcocaine hydrolysis by liver and serum esterases

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Cocaine metabolism in man: identification of four previously unreported cocaine metabolites in human urine.

21 January 2018

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Modulation of cocaine metabolism in primary rat hepatocyte cultures: effects on irreversible binding and protein biosynthesis.

21 January 2018

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12 December 2020

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12 December 2020

Electrochemistry of norcocaine nitroxide and related compounds: implications for cocaine hepatotoxicity.

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12 December 2020

Immunochemical analysis of acetaminophen covalent binding to proteins. Partial characterization of the major acetaminophen-binding liver proteins

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12 December 2020

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12 December 2020

Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies.

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12 December 2020

Ultrastructure of experimental cocaine hepatotoxicity

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12 December 2020

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

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12 December 2020

Sex and strain differences in response to cocaine.

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12 December 2020

Effects of subacute treatment with cocaine on activities of N-demethylase, UDP-glucuronyltransferase and sulfotransferase in WKY and SHR rat liver--sex and strain differences.

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12 December 2020

Substrate specificity of guinea pig liver flavin-containing monooxygenase for morphine, tropane and strychnos alkaloids

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12 December 2020

Antagonism of cocaine-induced hepatotoxicity by the alpha adrenergic antagonists phentolamine and yohimbine

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12 December 2020

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12 December 2020

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12 December 2020

Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism.

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12 December 2020

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12 December 2020

Effect of chronic ethanol feeding on rat hepatocytic glutathione. Compartmentation, efflux, and response to incubation with ethanol

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12 December 2020

Sex and strain differences in the hepatotoxic response to acute cocaine administration in the mouse.

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12 December 2020

Cocaine-induced liver cell injury: comparison of morphological features in man and in experimental models

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12 December 2020

Cocaine-induced hepatotoxicity in mice

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12 December 2020

Evidence of enhanced in vivo lipid peroxidation after acute cocaine administration.

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12 December 2020

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Cocaine toxicity in cultured rat hepatocytes.

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12 December 2020

Initiation of in vitro lipid peroxidation by N-hydroxynorcocaine and norcocaine nitroxide

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12 December 2020

Demethylation in rats chronically treated with cocaine

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12 December 2020

New, potent cocaine analogs: ligand binding and transport studies in rat striatum

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12 December 2020

Ethanol enhancement of cocaine-induced hepatotoxicity

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12 December 2020

Developmental expression of cocaine hepatotoxicity in the mouse.

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12 December 2020

Glutathione: toxicological implications

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12 December 2020

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12 December 2020

Involvement of FAD-containing monooxygenase in cocaine-induced hepatotoxicity.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Norcocaine nitroxide. A potential hepatotoxic metabolite of cocaine.

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12 December 2020

Histopathology of cocaine hepatotoxicity. Report of four patients.

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12 December 2020

Presence of the toxic metabolite N-hydroxy-norcocaine in brain and liver of the mouse

1 reference

12 December 2020

Differential effects of daily administration of cocaine on hepatic and cerebral glutathione in mice.

1 reference

12 December 2020

Prevention of acetaminophen and cocaine hepatotoxicity in mice by cimetidine treatment.

1 reference

12 December 2020

N-demethylation of cocaine to norcocaine. Evidence for participation by cytochrome P-450 and FAD-containing monooxygenase.

1 reference

12 December 2020

Determination of cocaine and norcocaine in plasma and cell cultures using high-performance liquid chromatography

1 reference

12 December 2020

Ethanol-induced enhancement of cocaine bioactivation and irreversible protein binding: evidence against a role of cytochrome P-450IIE1.

1 reference

12 December 2020

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12 December 2020

Cocaine-induced biochemical changes and cytotoxicity in hepatocytes isolated from both mice and rats.

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12 December 2020

Reactive intermediates and their toxicological significance

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12 December 2020

Sensitivity difference to hepatotoxicity of cocaine in spontaneously hypertensive and Wistar Kyoto rats

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12 December 2020

Potentiation of cocaine-mediated hepatotoxicity by acute and chronic ethanol.

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12 December 2020

Acute cocaine-induced hepatotoxicity in DBA/2Ha male mice.

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12 December 2020

Physiological disposition and biotransformation of (3H) cocaine in acutely and chronically treated rats

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12 December 2020

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12 December 2020

Metabolism of cocaine and norcocaine to N-hydroxynorcocaine.

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12 December 2020

Cocaine-induced hepatic necrosis in mice—The role of cocaine metabolism

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12 December 2020

Role of protein binding in cocaine-induced hepatic necrosis.

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12 December 2020

Cocaine hepatotoxicity in cultured liver slices: a species comparison.

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12 December 2020

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12 December 2020

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12 December 2020

Hepatic Dysfunction in Heroin and Cocaine Users

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12 December 2020

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12 December 2020

Liver damage from cocaine in mice

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12 December 2020

Reactive oxygen species and non-peroxidative mechanisms of cocaine-induced cytotoxicity in rat hepatocyte cultures

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12 December 2020

Cocaethylene: a unique cocaine metabolite displays high affinity for the dopamine transporter

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12 December 2020

Hepatic periportal necrosis induced by chronic administration of cocaine.

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12 December 2020

Acetaminophen hepatotoxicity: correspondence of selective protein arylation in human and mouse liver in vitro, in culture, and in vivo

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12 December 2020

Liver function tests in non-parenteral cocaine users.

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12 December 2020

Identifiers

DOI

10.1007/BF02284256

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20 August 2017

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