(Q37419313)

20 August 2017

2 references

25 October 2022

Progress in the therapeutic applications of siRNAs against HIV-1. (English)

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20 August 2017

author name string

Miguel Angel Martínez

series ordinal

1

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20 August 2017

language of work or name

English

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publication date

1 January 2009

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Methods in Molecular Biology

20 August 2017

published in

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20 August 2017

25 October 2022

487

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20 August 2017

page(s)

343-368

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Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

20 August 2017

cites work

1 reference

12 December 2020

Inhibition of retroviral pathogenesis by RNA interference.

1 reference

12 December 2020

Effective suppression of human immunodeficiency virus type 1 through a combination of short- or long-hairpin RNAs targeting essential sequences for retroviral integration

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12 December 2020

In vivo activity of nuclease-resistant siRNAs

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12 December 2020

Human immunodeficiency virus type 1 escape from RNA interference

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12 December 2020

Quantification of integrated and total HIV-1 DNA after long-term highly active antiretroviral therapy in HIV-1-infected patients

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12 December 2020

Modulation of HIV-1 replication by RNA interference

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12 December 2020

Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing.

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12 December 2020

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

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12 December 2020

Suppression of microRNA-silencing pathway by HIV-1 during virus replication

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12 December 2020

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

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12 December 2020

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

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12 December 2020

Second-generation shRNA libraries covering the mouse and human genomes

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12 December 2020

Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages

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12 December 2020

Recovery of replication-competent HIV despite prolonged suppression of plasma viremia

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12 December 2020

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

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12 December 2020

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

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12 December 2020

Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA.

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12 December 2020

On the delivery of small interfering RNAs into mammalian cells

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12 December 2020

Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype

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12 December 2020

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

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12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

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12 December 2020

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

1 reference

12 December 2020

Antiretroviral treatment of HIV infected adults

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12 December 2020

Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates

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12 December 2020

Identification of microRNAs of the herpesvirus family

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12 December 2020

Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing

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12 December 2020

Induction and suppression of RNA silencing: insights from viral infections

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12 December 2020

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

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12 December 2020

Endoribonuclease-prepared short interfering RNAs induce effective and specific inhibition of human immunodeficiency virus type 1 replication

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12 December 2020

Silencing of HIV-1 with RNA interference: a multiple shRNA approach

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12 December 2020

Type 1 interferons and the virus-host relationship: a lesson in détente .

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12 December 2020

Expression profiling reveals off-target gene regulation by RNAi

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12 December 2020

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

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12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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12 December 2020

Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes

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12 December 2020

The inner-nuclear-envelope protein emerin regulates HIV-1 infectivity

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12 December 2020

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

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12 December 2020

Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions

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12 December 2020

RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication

1 reference

12 December 2020

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

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12 December 2020

Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency

1 reference

12 December 2020

Interferon modulation of cellular microRNAs as an antiviral mechanism

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12 December 2020

"UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infection

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12 December 2020

Induction and suppression of RNA silencing by an animal virus

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12 December 2020

Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages

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12 December 2020

Insertional mutagenesis in gene therapy and stem cell biology

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12 December 2020

Cationic liposome-mediated delivery of siRNAs in adult mice

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12 December 2020

Analysis of the interaction of primate retroviruses with the human RNA interference machinery

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12 December 2020

Experimental models to study development and function of the human immune system in vivo

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12 December 2020

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer

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12 December 2020

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

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12 December 2020

Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA.

1 reference

12 December 2020

Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome

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12 December 2020

Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors

1 reference

12 December 2020

Design of HIV vectors for efficient gene delivery into human hematopoietic cells

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12 December 2020

Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference

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12 December 2020

Inhibition of respiratory viruses by nasally administered siRNA.

1 reference

12 December 2020

Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA.

1 reference

12 December 2020

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

1 reference

12 December 2020

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

12 December 2020

siRNA-directed inhibition of HIV-1 infection

1 reference

12 December 2020

A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs

1 reference

12 December 2020

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

1 reference

12 December 2020

An essential role for LEDGF/p75 in HIV integration

1 reference

12 December 2020

Viral dynamics in human immunodeficiency virus type 1 infection

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12 December 2020

Lentivirus-mediated RNA interference therapy for human immunodeficiency virus type 1 infection

1 reference

12 December 2020

MicroRNAs modulate hematopoietic lineage differentiation

1 reference

12 December 2020

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

1 reference

12 December 2020

Dissecting HIV-1 through RNA interference

1 reference

12 December 2020

Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication

1 reference

12 December 2020

Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells

1 reference

12 December 2020

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

1 reference

12 December 2020

RNA interference and innate immunity

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12 December 2020

Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1).

1 reference

12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

12 December 2020

Interfering with disease: a progress report on siRNA-based therapeutics

1 reference

12 December 2020

Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells

1 reference

12 December 2020

Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro

1 reference

12 December 2020

Recombination: Multiply infected spleen cells in HIV patients

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12 December 2020

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

1 reference

12 December 2020

Is RNA interference involved in intrinsic antiviral immunity in mammals?

1 reference

12 December 2020

Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations

1 reference

12 December 2020

Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference

1 reference

12 December 2020

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

1 reference

12 December 2020

Transduction of cell lines and primary cells by FIV-packaged HIV vectors

1 reference

12 December 2020

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

1 reference

12 December 2020

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

12 December 2020

Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference

1 reference

12 December 2020

A systematic analysis of the effect of target RNA structure on RNA interference

1 reference

12 December 2020

Viruses as quasispecies: biological implications

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12 December 2020

The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference

1 reference

12 December 2020

RNA interference of HIV replication

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12 December 2020

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

1 reference

12 December 2020

Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway

1 reference

12 December 2020

Time to hit HIV, early and hard.

1 reference

12 December 2020

Gene Expression Analysis in Blood Cells in Response to Unmodified and 2′-Modified siRNAs Reveals TLR-dependent and Independent Effects

1 reference

12 December 2020

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

1 reference

12 December 2020

Effective anti-hepatitis B virus hammerhead ribozymes derived from multimeric precursors

1 reference

12 December 2020

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice

1 reference

12 December 2020

siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells

1 reference

12 December 2020

Design of extended short hairpin RNAs for HIV-1 inhibition

1 reference

12 December 2020

Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector

1 reference

12 December 2020

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

12 December 2020

Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference

1 reference

12 December 2020

The survival benefits of AIDS treatment in the United States

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12 December 2020

The Ebola virus VP35 protein is a suppressor of RNA silencing

1 reference

12 December 2020

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

1 reference

12 December 2020

Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort

1 reference

12 December 2020

Update of the drug resistance mutations in HIV-1: 2007.

1 reference

12 December 2020

Optimization and characterization of tRNA-shRNA expression constructs

1 reference

12 December 2020

Sequence homology required by human immunodeficiency virus type 1 to escape from short interfering RNAs.

1 reference

12 December 2020

An HIV vaccine--evolving concepts

1 reference

12 December 2020

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

12 December 2020

Host immune system gene targeting by a viral miRNA

1 reference

12 December 2020

Gene therapy targeting peripheral blood CD34+ hematopoietic stem cells of HIV-infected individuals

1 reference

12 December 2020

Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.

1 reference

12 December 2020

siRNA function in RNAi: a chemical modification analysis

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12 December 2020

Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV

1 reference

12 December 2020

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

1 reference

12 December 2020

Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors.

1 reference

12 December 2020

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

1 reference

12 December 2020

Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses

1 reference

12 December 2020

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

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12 December 2020

HIV entry inhibitors.

1 reference

12 December 2020

10.1007/978-1-60327-547-7_17

Identifiers

DOI

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20 August 2017

0 references

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