(Q37424805)

20 August 2017

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title

The ubiquitylation machinery of the endoplasmic reticulum (English)

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20 August 2017

main subject

endoplasmic reticulum

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Christian Hirsch

1

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20 August 2017

Robert Gauss

2

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20 August 2017

Sabine C Horn

3

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20 August 2017

Oliver Neuber

4

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20 August 2017

Thomas Sommer

5

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20 August 2017

language of work or name

English

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publication date

1 March 2009

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20 August 2017

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20 August 2017

volume

458

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20 August 2017

issue

7237

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20 August 2017

page(s)

453-460

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https://scigraph.springernature.com/pub.10.1038/nature07962

20 August 2017

exact match

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cites work

Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07962

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07962

Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07962

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07962

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

21 January 2018

1 reference

12 December 2020

Defining the glycan destruction signal for endoplasmic reticulum-associated degradation

1 reference

12 December 2020

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

1 reference

12 December 2020

PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase

1 reference

12 December 2020

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

1 reference

12 December 2020

Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins

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12 December 2020

An Adaptable Standard for Protein Export from the Endoplasmic Reticulum

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12 December 2020

EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

1 reference

12 December 2020

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

1 reference

12 December 2020

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

1 reference

12 December 2020

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

1 reference

12 December 2020

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

1 reference

12 December 2020

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

1 reference

12 December 2020

Ubx2 links the Cdc48 complex to ER-associated protein degradation

1 reference

12 December 2020

A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation

1 reference

12 December 2020

N-linked glycans direct the cotranslational folding pathway of influenza hemagglutinin.

1 reference

12 December 2020

A membrane protein required for dislocation of misfolded proteins from the ER

1 reference

12 December 2020

D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?

1 reference

12 December 2020

Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

1 reference

12 December 2020

Central pore residues mediate the p97/VCP activity required for ERAD

1 reference

12 December 2020

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

1 reference

12 December 2020

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

1 reference

12 December 2020

Roles of N-linked glycans in the endoplasmic reticulum

1 reference

12 December 2020

The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation

1 reference

12 December 2020

Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

1 reference

12 December 2020

N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control

1 reference

12 December 2020

TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

1 reference

12 December 2020

Proteolysis and sterol regulation

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12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

12 December 2020

A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

1 reference

12 December 2020

Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp

1 reference

12 December 2020

Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.

1 reference

12 December 2020

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

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12 December 2020

BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex

1 reference

12 December 2020

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

1 reference

12 December 2020

EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.

1 reference

12 December 2020

Ubiquitination is required for the retro-translocation of a short-lived luminal endoplasmic reticulum glycoprotein to the cytosol for degradation by the proteasome

1 reference

12 December 2020

Rad23 provides a link between the Png1 deglycosylating enzyme and the 26 S proteasome in yeast.

1 reference

12 December 2020

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

1 reference

12 December 2020

Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

1 reference

12 December 2020

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

1 reference

12 December 2020

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

12 December 2020

Glycoprotein biosynthesis in Saccharomyces cerevisiae. Isolation and characterization of the gene encoding a specific processing alpha-mannosidase

1 reference

12 December 2020

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

1 reference

12 December 2020

Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation

1 reference

12 December 2020

Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation.

1 reference

12 December 2020

Energetic characteristics of the new transthyretin variant A25T may explain its atypical central nervous system pathology.

1 reference

12 December 2020

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

1 reference

12 December 2020

Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation

1 reference

12 December 2020

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

1 reference

12 December 2020

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

1 reference

12 December 2020

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

1 reference

12 December 2020

A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins

1 reference

12 December 2020

Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure

1 reference

12 December 2020

E3 ubiquitin ligase that recognizes sugar chains

1 reference

12 December 2020

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

A cryptic protease couples deubiquitination and degradation by the proteasome

1 reference

12 December 2020

Glycoprotein biosynthesis in Saccharomyces cerevisiae. Purification of the alpha-mannosidase which removes one specific mannose residue from Man9GlcNAc

1 reference

12 December 2020

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

1 reference

12 December 2020

The COPII cage: unifying principles of vesicle coat assembly

1 reference

12 December 2020

EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming

1 reference

12 December 2020

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1 reference

12 December 2020

Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.

1 reference

12 December 2020

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

1 reference

12 December 2020

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

1 reference

12 December 2020

Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation

1 reference

12 December 2020

A role for N-glycanase in the cytosolic turnover of glycoproteins

1 reference

12 December 2020

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

1 reference

12 December 2020

SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER.

1 reference

12 December 2020

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

1 reference

12 December 2020

Role of Cue1p in ubiquitination and degradation at the ER surface

1 reference

12 December 2020

SEL1L and HRD1 are involved in the degradation of unassembled secretory Ig-mu chains

1 reference

12 December 2020

Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis

1 reference

12 December 2020

Molecular cloning and expression of a 26 S protease subunit enriched in dileucine repeats

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12 December 2020

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

1 reference

12 December 2020

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway

1 reference

12 December 2020

Proteasome subunit Rpn13 is a novel ubiquitin receptor

1 reference

12 December 2020

CHIP: a link between the chaperone and proteasome systems

1 reference

12 December 2020

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

1 reference

12 December 2020

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

1 reference

12 December 2020

Substrate-specific requirements for UGT1-dependent release from calnexin

1 reference

12 December 2020

Structure of the AAA ATPase p97

1 reference

12 December 2020

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

1 reference

12 December 2020

The biological and chemical basis for tissue-selective amyloid disease

1 reference

12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

12 December 2020

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

1 reference

12 December 2020

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

1 reference

12 December 2020

A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1

1 reference

12 December 2020

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

1 reference

12 December 2020

N-glycan structure dictates extension of protein folding or onset of disposal

1 reference

12 December 2020

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

1 reference

12 December 2020

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

1 reference

12 December 2020

Ubiquitin ligase gp78 increases solubility and facilitates degradation of the Z variant of alpha-1-antitrypsin

1 reference

12 December 2020

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

1 reference

12 December 2020

Initial sequencing and analysis of the human genome

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE07962

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Dimensions Publication ID

20 August 2017

1019048030

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