(Q37424818)

20 August 2017

Genome mining unveils widespread natural product biosynthetic capacity in human oral microbe Streptococcus mutans (English)

1 reference

20 August 2017

1 reference

Streptococcus mutans

1 reference

Geoff P Horsman

4

0 references

author name string

Liwei Liu

1

1 reference

20 August 2017

Tingting Hao

2

1 reference

20 August 2017

Zhoujie Xie

3

1 reference

20 August 2017

Yihua Chen

5

1 reference

20 August 2017

language of work or name

English

0 references

publication date

21 November 2016

1 reference

20 August 2017

1 reference

20 August 2017

6

1 reference

20 August 2017

37479

1 reference

https://scigraph.springernature.com/pub.10.1038/srep37479

20 August 2017

0 references

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Exploring and Understanding the Biochemical Diversity of the Human Microbiota

23 August 2017

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Bioactive natural products from novel microbial sources.

23 August 2017

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Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases

23 August 2017

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Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes

23 August 2017

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HUMAN MICROBIOTA. Small molecules from the human microbiota

23 August 2017

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antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

23 August 2017

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Recent advances in genome mining of secondary metabolites in Aspergillus terreus

23 August 2017

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Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria.

23 August 2017

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A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.

23 August 2017

1 reference

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Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes.

23 August 2017

1 reference

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Bacteriocins - a viable alternative to antibiotics?

23 August 2017

1 reference

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Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

23 August 2017

1 reference

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Structure and biosynthesis of the antibiotic bottromycin D

23 August 2017

1 reference

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Thoughts and facts about antibiotics: where we are now and where we are heading

23 August 2017

1 reference

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The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity

23 August 2017

1 reference

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Type III polyketide synthases in natural product biosynthesis

23 August 2017

1 reference

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Genome mining demonstrates the widespread occurrence of gene clusters encoding bacteriocins in cyanobacteria

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Structure and genetics of circular bacteriocins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

CDD: a Conserved Domain Database for the functional annotation of proteins

23 August 2017

1 reference

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Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Nonribosomal peptide synthetases: structures and dynamics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

PKS and NRPS release mechanisms

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Natural products in drug discovery: present status and perspectives

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Identification of nlmTE, the locus encoding the ABC transport system required for export of nonlantibiotic mutacins in Streptococcus mutans

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Evolutionary implications of bacterial polyketide synthases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

WebLogo: A Sequence Logo Generator

23 August 2017

1 reference

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Genetically modified Streptococcus mutans for the prevention of dental caries

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Polyketide biosynthesis: a millennium review

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Purification of mutacin III from group III Streptococcus mutans UA787 and genetic analyses of mutacin III biosynthesis genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Lantibiotics: biosynthesis and biological activities of uniquely modified peptides from gram-positive bacteria

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

A new enzyme superfamily - the phosphopantetheinyl transferases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

The leader peptide of mutacin 1140 has distinct structural components compared to related class I lantibiotics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Competition and coexistence between Streptococcus mutans and Streptococcus sanguinis in the dental biofilm

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

The group I strain of Streptococcus mutans, UA140, produces both the lantibiotic mutacin I and a nonlantibiotic bacteriocin, mutacin IV.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Purification and biochemical characterization of mutacin I from the group I strain of Streptococcus mutans, CH43, and genetic analysis of mutacin I biosynthesis genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Regulation of the competence pathway as a novel role associated with a streptococcal bacteriocin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Bacteriocin (mutacin) production by Streptococcus mutans genome sequence reference strain UA159: elucidation of the antimicrobial repertoire by genetic dissection.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Fungal biofilm inhibitors from a human oral microbiome-derived bacterium.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Requirements of the engineered leader peptide of nisin for inducing modification, export, and cleavage.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Genomic island TnSmu2 of Streptococcus mutans harbors a nonribosomal peptide synthetase-polyketide synthase gene cluster responsible for the biosynthesis of pigments involved in oxygen and H2O2 tolerance.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Peptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

SMU.152 acts as an immunity protein for mutacin IV.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

Isolation and partial characterization of the Streptococcus mutans type AII lantibiotic mutacin K8.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5116633

4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP37479

Detection of modified amino acids in lantibiotic peptide mutacin II by chemical derivation and electrospray ionization-mass spectroscopic analysis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869143

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chain termination steps in nonribosomal peptide synthetase assembly lines: directed acyl-S-enzyme breakdown in antibiotic and siderophore biosynthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869143

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Frequency and expression of mutacin biosynthesis genes in isolates of Streptococcus mutans with different mutacin-producing phenotypes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869143

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP37479

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

27869143

1 reference