(Q37428620)

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Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation (English)

1 reference

Europe PubMed Central

20 August 2017

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10

object named as

Lena Kjellén

1 reference

Europe PubMed Central

20 August 2017

Susan M Schlenner

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Hans-Reimer Rodewald

9

object named as

Hans-Reimer Rodewald

1 reference

Europe PubMed Central

20 August 2017

author name string

Ananya Roy

1

1 reference

Europe PubMed Central

20 August 2017

Goutham Ganesh

2

1 reference

Europe PubMed Central

20 August 2017

Helena Sippola

3

1 reference

Europe PubMed Central

20 August 2017

Sara Bolin

4

1 reference

Europe PubMed Central

20 August 2017

Osama Sawesi

5

1 reference

Europe PubMed Central

20 August 2017

Anders Dagälv

6

1 reference

Europe PubMed Central

20 August 2017

Susan M Schlenner

7

1 reference

Europe PubMed Central

20 August 2017

Thorsten Feyerabend

8

1 reference

Europe PubMed Central

20 August 2017

Lars Hellman

11

1 reference

Europe PubMed Central

20 August 2017

Magnus Åbrink

12

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Europe PubMed Central

20 August 2017

language of work or name

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publication date

20 November 2013

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Europe PubMed Central

20 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

20 August 2017

289

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Europe PubMed Central

20 August 2017

1

1 reference

Europe PubMed Central

20 August 2017

237-250

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Europe PubMed Central

20 August 2017

The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

A case of mistaken identity: HSPs are no DAMPs but DAMPERs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

HMGB1 is a therapeutic target for sterile inflammation and infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cell-orchestrated immunity to pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cell proteases: multifaceted regulators of inflammatory disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Immunomodulatory mast cells: negative, as well as positive, regulators of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

How dying cells alert the immune system to danger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Proteases in parasitic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cell proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cell-dependent activation of pro matrix metalloprotease 2: A role for serglycin proteoglycan-dependent mast cell proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

DAMPs, PAMPs and alarmins: all we need to know about danger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cells can enhance resistance to snake and honeybee venoms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Alarmin(g) news about danger: workshop on innate danger signals and HMGB1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Serglycin is essential for maturation of mast cell secretory granule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Development and evaluation of a Western blot kit for diagnosis of human trichinellosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Virulence and the heat shock response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Heparin is essential for the storage of specific granule proteases in mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Delayed expulsion of adult Trichinella spiralis by mast cell-deficient W/Wv mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Heat shock proteins as virulence factors of pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Protein folding in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

23 August 2017

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

14 September 2017

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

14 September 2017

Generation of therapeutic antibody responses against IgE through vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

14 September 2017

Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

28 September 2017

CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

28 September 2017

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

28 September 2017

Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

28 September 2017

Loss of histochemical identity in mast cells lacking carboxypeptidase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

26 June 2018

Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

26 June 2018

Heat shock proteins are no DAMPs, rather 'DAMPERs'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4+ memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Cytokine production by skin-derived mast cells: endogenous proteases are responsible for degradation of cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879547

2 September 2018

Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24257755

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24257755

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peritoneal cell-derived mast cells: an in vitro model of mature serosal-type mouse mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24257755

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast Cells as Sensors of Cell Injury through IL-33 Recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/24257755

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of mast cell-bacteria interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/24257755

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.435156

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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